{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:13:07Z","timestamp":1760955187151},"reference-count":56,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2010,2,25]],"date-time":"2010-02-25T00:00:00Z","timestamp":1267056000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2010,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose:<\/jats:title><jats:p>To assess added value of a new time\u2010resolved technique with temporal interpolation and stochastic spiral trajectory through <jats:italic>k<\/jats:italic>\u2010space and parallel imaging (TR\u2010MRA) to conventional bolus chase MRA (BC\u2010MRA) for infragenual peripheral artery evaluation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods:<\/jats:title><jats:p>An institutional review board\u2010approved retrospective review of peripheral arterial disease patients was performed. Infragenual TR\u2010MRA and BC\u2010MRA were performed in 26 patients over four months. Two readers individually assessed image quality, diagnostic confidence, and stenosis severity and length in 13 defined below knee segments, first with BC\u2010MRA alone, and then with a combined BC\u2010MRA and TR\u2010MRA reading (BC+TR\u2010MRA). Perceived contribution of TR\u2010MRA was rated by each reader. The reference standard was a consensus reading of both sequences. Catheter angiographic (CA) correlation was available in 6 patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>A total of 646 infragenual segments in 51 extremities were evaluated. Image quality and diagnostic confidence were superior for BC+TR\u2010MRA compared with BC\u2010MRA alone (<jats:italic>P<\/jats:italic> &lt; 0.001). Adding TR\u2010MRA improved sensitivity (85.7% versus 80.7%; <jats:italic>P<\/jats:italic> &lt; 0.05) and diagnostic accuracy (88.1% versus 85.4%; <jats:italic>P<\/jats:italic> &lt; 0.05) for hemodynamically significant stenosis. Venous contamination (0% versus 13.1% segments) and motion (0.9% versus 8.0%) were decreased for BC+TR\u2010MRA versus BC\u2010MRA alone, <jats:italic>P<\/jats:italic> &lt; 0.01. For BC+TR\u2010MRA, TR\u2010MRA was rated more useful than BC\u2010MRA in 30\/51 legs (58.8%). TR\u2010MRA identified retrograde flow in 5 segments. Where available, there was high concordance between CA and BC+TR\u2010MRA (91.6%) for stenosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>Adding TR\u2010MRA with temporal interpolation and stochastic spiral trajectories to bolus chase MRA improves image quality, diagnostic confidence and accuracy. It provides hemodynamic information and minimizes venous contamination and patient motion. J. Magn. Reson. 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