{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T06:48:41Z","timestamp":1696920521874},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2010,3,29]],"date-time":"2010-03-29T00:00:00Z","timestamp":1269820800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2010,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose:<\/jats:title><jats:p>To compare two data\u2010driven methods of statistical image analysis, principal and independent component analysis (PCA, ICA), in identifying neural networks related to the transient occurrence of phosphenes experienced by a female patient subsequent to a brain infarct.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods:<\/jats:title><jats:p>An initial functional magnetic resonance imaging (fMRI) session consisted of two acquisitions: one of the patient experiencing phosphenes and a second responding to a well\u2010defined visual stimulation paradigm. A second fMRI session 6 months later, when the patient no longer experienced phosphenes, consisted of an acquisition in which no stimulation was presented. Analysis of correlations between the temporal expression coefficients and models of the hemodynamic response identified salient components. Spectral analysis confirmed the identification. The phosphene model was based solely on the subjective report of the patient.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Both methods revealed occipital cortical and subcortical areas known to be sites for visual information\u2010processing during stimulation, as did SPM. In addition, higher\u2010order visual areas such as the precuneus and the lateral parietal cortex were implicated in the PCA of the phosphenes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>The analyses suggest the capability of data\u2010driven approaches to identify the brain structures involved in these transient, spontaneous visual events. J. Magn. Reson. Imaging 2010;31:821\u2013828. \u00a92010 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.22122","type":"journal-article","created":{"date-parts":[[2010,3,29]],"date-time":"2010-03-29T22:26:50Z","timestamp":1269901610000},"page":"821-828","source":"Crossref","is-referenced-by-count":2,"title":["Data\u2010driven analyses of an fMRI study of a subject experiencing phosphenes"],"prefix":"10.1002","volume":"31","author":[{"given":"John H.","family":"Missimer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R\u00fcdiger J.","family":"Seitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raimund","family":"Kleiser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,3,29]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.460020108"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-199903000-00016"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2000.0554"},{"key":"e_1_2_6_5_2","first-page":"49","article-title":"Comparison of independent component analysis and conventional hypothesis\u2010driven analysis for clinical functional MR image processing","volume":"23","author":"Quigley MA","year":"2002","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1006\/nimg.2002.1122"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00736.2004"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1006\/nimg.2001.0914"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0361-9230(00)00438-X"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0193(1998)6:3<160::AID-HBM5>3.0.CO;2-1"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2004.10.043"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.10034"},{"key":"e_1_2_6_13_2","volume-title":"Co\u2010planar stereotaxic atlas of the human brain. 3\u2010dimensional proportional system. 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