{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:14:21Z","timestamp":1760955261932},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2010,9,29]],"date-time":"2010-09-29T00:00:00Z","timestamp":1285718400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2010,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To prospectively study the diagnostic performance of hybrid single\u2010dose contrast\u2010enhanced MRA of peripheral arterial disease (PAD), with digital subtraction angiography (DSA) as the reference standard.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Hybrid MRA, combining time resolved imaging of contrast kinetics and two\u2010station bolus\u2010chase sequences, of lower limb was performed in 31 PAD patients (21 men, 10 women; mean age, 72 years) with two separate gadobenate dimeglumine (8 mL) injections in each sequence. Two independent blinded readers analyzed the vascular stenosis (32 segments in each limb). Sensitivity, specificity, and accuracy in all vascular segments and segments below popliteal artery were calculated. Interobserver agreements on MRA and intermodality agreements between MRA and DSA were calculated by using k statistics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sensitivity, specificity, and accuracy of the hybrid MRA with regard to hemodynamically significant stenosis in all vascular segments were 92%, 97%, and 95% for reader 1, and 90%, 92%, and 92%, for reader 2, respectively. The interobsever agreements on MRA were good (k = 0.77\u20130.74) for all\u2010grade stenosis, and excellent (k = 0.82\u20130.81) for hemadynamically significant stenosis. The intermodality agreements are good to excellent (k = 0.73\u20130.94).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Single\u2010dose hybrid MRA is a safe and reliable noninvasive alternative to conventional DSA in the assessment of PAD patients. J. Magn. Reson. Imaging 2010;32:935\u2013942. \u00a9 2010 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.22341","type":"journal-article","created":{"date-parts":[[2010,9,29]],"date-time":"2010-09-29T11:01:37Z","timestamp":1285758097000},"page":"935-942","source":"Crossref","is-referenced-by-count":19,"title":["Single\u2010dose time\u2010resolved contrast enhanced hybrid MR angiography in diagnosis of peripheral arterial disease: Compared with digital subtraction angiography"],"prefix":"10.1002","volume":"32","author":[{"given":"Chun\u2010Chieh","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huei\u2010Lung","family":"Liang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chia\u2010Chi","family":"Hsiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matt Chiung\u2010Yu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"To\u2010Ho","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chieh\u2010Jen","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jer\u2010Shyung","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yih\u2010Huei","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huay\u2010Ben","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,9,29]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200105243442108"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/1520-7560(200009\/10)16:1 <::AID-DMRR131>3.0.CO;2-W"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.182.1.1727290"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.179.4.1791013"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1583\/03-1144.1"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.206.3.9494487"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.174.1.1740171"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1053\/ejvs.2002.1730"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1067\/mva.2002.119505"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.214.2.r00fe42325"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004424-200103000-00006"},{"key":"e_1_2_5_13_2","first-page":"511","article-title":"Comparison of auto\u2010moving table contrast\u2010enhanced 3\u2010D MRA and iodinated contrast\u2010enhanced DSA for evaluation the lower\u2010extremity arteries","volume":"67","author":"Ho CF","year":"2004","journal-title":"J Chin Med Assoc"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2241011338"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2251011292"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1177\/000331970405500202"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2422051111"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.21973"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2343031685"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(02)01406-X"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199206113262428"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1051-0443(07)61401-8"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.175.5.1751291"},{"key":"e_1_2_5_24_2","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.04.1111"},{"key":"e_1_2_5_25_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2211010119"},{"key":"e_1_2_5_26_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2004-814664"},{"key":"e_1_2_5_27_2","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.05.0388"},{"key":"e_1_2_5_28_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2401041225"},{"key":"e_1_2_5_29_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2351031987"},{"key":"e_1_2_5_30_2","unstructured":"FinnJP FrancoisCJ MooreJR NiemczuraR. Lower extremity MRA with full prior specification of bolus transit times. In: Proceedings of the 10th Annual Meeting of the ISMRM Berkeley 2002. (abstract 266)."},{"key":"e_1_2_5_31_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.183.4.1831041"},{"key":"e_1_2_5_32_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2461071267"},{"key":"e_1_2_5_33_2","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2006060601"},{"key":"e_1_2_5_34_2","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.06.1094"},{"key":"e_1_2_5_35_2","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.07.0047"},{"key":"e_1_2_5_36_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2362040895"},{"key":"e_1_2_5_37_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.301.4.415"},{"key":"e_1_2_5_38_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.180.4.1801085"},{"key":"e_1_2_5_39_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-009-1555-7"}],"container-title":["Journal of Magnetic Resonance Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmri.22341","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmri.22341","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,8]],"date-time":"2023-10-08T19:55:01Z","timestamp":1696794901000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmri.22341"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9,29]]},"references-count":38,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2010,10]]}},"alternative-id":["10.1002\/jmri.22341"],"URL":"https:\/\/doi.org\/10.1002\/jmri.22341","archive":["Portico"],"relation":{},"ISSN":["1053-1807","1522-2586"],"issn-type":[{"value":"1053-1807","type":"print"},{"value":"1522-2586","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,9,29]]}}}