{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T08:42:30Z","timestamp":1791016950434,"version":"4.1.0"},"reference-count":38,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2011,5,17]],"date-time":"2011-05-17T00:00:00Z","timestamp":1305590400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2011,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose:<\/jats:title><jats:p>To evaluate the MR agreement of cardiac function parameters between volumetric (cine SSFP) and phase contrast flow (PC\u2010flow) assessment in patients with repaired tetralogy of Fallot (r\u2010TOF) and chronic pulmonary regurgitation (PR) at rest and under dobutamine stress (DS\u2010MR).<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods:<\/jats:title><jats:p>We studied 18 patients with r\u2010TOF and severe chronic PR (34 \u00b1 12.7 years, PR fraction<jats:sub>[flow]<\/jats:sub> 44 \u00b1 15%) by cardiac MR at rest, 10 and 20 \u03bcg\/kg\/min of dobutamine. We compared analogous functional parameters by volumetry and PC\u2010flow: (i) Systemic output [left ventricle stroke volume (LV<jats:sub>SV<\/jats:sub>) versus aortic forward flow (AO<jats:sub>FF<\/jats:sub>)], (ii) Pulmonary output [right ventricle stroke volume (RV<jats:sub>SV<\/jats:sub>) versus pulmonary forward flow (PA<jats:sub>FF<\/jats:sub>)], (iii) PR volume [(RV<jats:sub>SV<\/jats:sub>\u2010LV<jats:sub>SV<\/jats:sub>) versus pulmonary backward flow (PA<jats:sub>BF<\/jats:sub>)], (iv) PR fraction [(RV<jats:sub>SV<\/jats:sub>\u2010LV<jats:sub>SV<\/jats:sub>\/RV<jats:sub>SV<\/jats:sub>) versus (PA<jats:sub>BF<\/jats:sub>\/PA<jats:sub>FF<\/jats:sub>)].<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>We found excellent Bland\u2010Altman agreement (mean difference \u00b1 limits of agreement, mL\/beat\/m<jats:sup>2<\/jats:sup>) at rest for both the systemic (\u22120.8 \u00b1 5.7) and pulmonary strokes volumes (\u22120.1 \u00b1 7.6), which slightly deteriorates during DS\u2010MR. The PR volume showed acceptable agreement at rest (\u22123.6 \u00b1 15.1), but also further deteriorated during stress (5.4 \u00b1 24). In contrast, the PR fraction showed poor agreement equally at rest (\u22125.6 \u00b1 22.8) and DS\u2010MR (3.2 \u00b1 19.2).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>In r\u2010TOF with chronic PR, analogous functional parameters should not be used interchangeably between volumetric and PC\u2010flow assessment during DS\u2010MR evaluation. J. Magn. Reson. Imaging 2011;33:1341\u20131350. \u00a9 2011 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.22573","type":"journal-article","created":{"date-parts":[[2011,5,17]],"date-time":"2011-05-17T22:14:55Z","timestamp":1305670495000},"page":"1341-1350","source":"Crossref","is-referenced-by-count":14,"title":["Cardiovascular MR dobutamine stress in adult tetralogy of fallot: Disparity between CMR volumetry and flow for cardiovascular 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