{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T16:45:19Z","timestamp":1782319519654,"version":"3.54.5"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,7,14]],"date-time":"2011-07-14T00:00:00Z","timestamp":1310601600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2011,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose:<\/jats:title><jats:p>To employ magnetic resonance tissue phase mapping (TPM) for the assessment of age\u2010related left ventricular (LV) synchrony of radial and long\u2010axis motion in healthy volunteers and in hypertensive heart disease, dilated cardiomyopathy (DCM), and left bundle branch block (LBBB).<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods:<\/jats:title><jats:p>TPM (spatial\/temporal resolution = 1.3 \u00d7 2.6 mm<jats:sup>2<\/jats:sup>\/13.8 msec) was employed to measure radial and long\u2010axis myocardial velocities in 58 healthy volunteers of three age groups and 37 patients (hypertensive, <jats:italic>n<\/jats:italic> = 18; DCM, <jats:italic>n<\/jats:italic> = 12; DCM and LBBB <jats:italic>n<\/jats:italic> = 7). Regional times\u2010to\u2010peak velocities (TTP) in systole and diastole were derived for all LV segments. Four measures of dyssynchrony were defined as the standard deviation of systolic and diastolic TTP for radial and long\u2010axis motion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Systolic radial and diastolic long\u2010axis dyssynchrony was increased (<jats:italic>P<\/jats:italic> &lt; 0.01) in all patient groups compared to controls. Multiple regressions revealed a significant relationship of dyssynchrony with LV ejection fraction and mass for systolic radial (<jats:italic>P<\/jats:italic> &lt; 0.001 resp. <jats:italic>P<\/jats:italic> = 0.02), diastolic radial (<jats:italic>P<\/jats:italic> &lt; 0.001 resp. <jats:italic>P<\/jats:italic> &lt; 0.05), and long\u2010axis (<jats:italic>P<\/jats:italic> &lt; 0.001 resp. <jats:italic>P<\/jats:italic> = 0.001) motion. Diastolic dyssynchrony correlated with the LV remodeling index (<jats:italic>P<\/jats:italic> &lt; 0.05) and increased with age (<jats:italic>P<\/jats:italic> &lt; 0.03). Systolic long\u2010axis dyssynchrony was not influenced by disease or LV function.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>Radial systolic and long\u2010axis diastolic dyssynchrony were the most sensitive markers for altered dyssynchrony in hypertensive heart disease or DCM. Future studies are needed to evaluate the diagnostic value of TPM\u2010derived dyssynchrony parameters. J. Magn. Reson. Imaging 2011;. \u00a9 2011 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.22641","type":"journal-article","created":{"date-parts":[[2011,7,14]],"date-time":"2011-07-14T22:36:07Z","timestamp":1310682967000},"page":"518-525","source":"Crossref","is-referenced-by-count":17,"title":["Magnetic resonance tissue phase mapping: Analysis of age\u2010related and pathologically altered left ventricular radial and long\u2010axis dyssynchrony"],"prefix":"10.1002","volume":"34","author":[{"given":"D.","family":"F\u00f6ll","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Germann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Hennig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ch.","family":"Bode","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Markl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,7,14]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.01.078"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.10.024"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2007.04.008"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa013168"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1067\/mhj.2002.121264"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehl247"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.787408"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.743120"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/HCO.0b013e32830b3865"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.21634"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.108.813857"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.20703"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.20808"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.1880080417"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.10114"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1161\/hc0402.102975"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000133276.45198.A5"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2383041992"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2005.083592"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.01.078"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.104.508457"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1186\/1532-429X-11-50"},{"key":"e_1_2_5_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(88)90166-0"},{"key":"e_1_2_5_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.03.035"},{"key":"e_1_2_5_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)01883-1"},{"key":"e_1_2_5_27_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.01063.2002"}],"container-title":["Journal of Magnetic Resonance Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmri.22641","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmri.22641","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T00:23:35Z","timestamp":1696897415000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmri.22641"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7,14]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,9]]}},"alternative-id":["10.1002\/jmri.22641"],"URL":"https:\/\/doi.org\/10.1002\/jmri.22641","archive":["Portico"],"relation":{},"ISSN":["1053-1807","1522-2586"],"issn-type":[{"value":"1053-1807","type":"print"},{"value":"1522-2586","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,7,14]]}}}