{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T04:19:39Z","timestamp":1791173979781,"version":"4.1.0"},"reference-count":14,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2012,6,22]],"date-time":"2012-06-22T00:00:00Z","timestamp":1340323200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose:<\/jats:title><jats:p>To evaluate the effect of spatial (ie, number of sampling locations along the aorta) and temporal sampling density on aortic pulse wave velocity (PWV) assessment from velocity\u2010encoded MRI in patients with Marfan syndrome (MFS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods:<\/jats:title><jats:p>Twenty\u2010three MFS patients (12 men, mean age 36 \u00b1 14 years) were included. Three PWV\u2010methods were evaluated: 1) reference PWV<jats:sub>i.p.<\/jats:sub> from in\u2010plane velocity\u2010encoded MRI with dense temporal and spatial sampling; 2) conventional PWV<jats:sub>t.p.<\/jats:sub> from through\u2010plane velocity\u2010encoded MRI with dense temporal but sparse spatial sampling at three aortic locations; 3) EPI\u2010accelerated PWV<jats:sub>t.p.<\/jats:sub> with sparse temporal but improved spatial sampling at five aortic locations with acceleration by echo\u2010planar imaging (EPI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Despite inferior temporal resolution, EPI\u2010accelerated PWV<jats:sub>t.p.<\/jats:sub> showed stronger correlation (<jats:italic>r<\/jats:italic> = 0.92 vs. <jats:italic>r<\/jats:italic> = 0.65, <jats:italic>P<\/jats:italic> = 0.03) with reference PWV<jats:sub>i.p.<\/jats:sub> in the total aorta, with less error (8% vs. 16%) and variation (11% vs. 27%) as compared to conventional PWV<jats:sub>t.p.<\/jats:sub>. In the aortic arch, correlation was comparable for both EPI\u2010accelerated and conventional PWV<jats:sub>t.p.<\/jats:sub> with reference PWV<jats:sub>i.p.<\/jats:sub> (<jats:italic>r<\/jats:italic> = 0.66 vs. <jats:italic>r<\/jats:italic> = 0.67, <jats:italic>P<\/jats:italic> = 0.46), albeit 92% scan\u2010time reduction by EPI\u2010acceleration.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>Improving spatial sampling density by adding two acquisition planes along the aorta results in more accurate PWV assessment, even when temporal resolution decreases. For regional PWV assessment in the aortic arch, EPI\u2010accelerated and conventional PWV assessment are comparably accurate. Scan\u2010time reduction makes EPI\u2010accelerated PWV assessment the preferred method of choice. J. Magn. Reson. Imaging 2012; 36:1470\u20131476. \u00a9 2012 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.23729","type":"journal-article","created":{"date-parts":[[2012,6,22]],"date-time":"2012-06-22T23:06:25Z","timestamp":1340406385000},"page":"1470-1476","source":"Crossref","is-referenced-by-count":13,"title":["Evaluation of sampling density on the accuracy of aortic pulse wave velocity from velocity\u2010encoded MRI in patients with Marfan syndrome"],"prefix":"10.1002","volume":"36","author":[{"given":"Eleanore S.J.","family":"Kr\u00f6ner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rob J.","family":"van der Geest","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur J.H.A.","family":"Scholte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia 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