{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:44:38Z","timestamp":1760147078354},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,5,6]],"date-time":"2013-05-06T00:00:00Z","timestamp":1367798400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>To use MR with diffusion tensor imaging (DTI) and conventional and high <jats:italic>b<\/jats:italic> value to assess diffusion changes in normal\u2010appearing white matter (NAWM) in patients with unilateral, severe stenosis, or occlusion of the middle cerebral artery (MCA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>In total, 28 patients with NAWM and unilateral, severe stenosis, or occlusion of the MCA underwent DTI with <jats:italic>b<\/jats:italic> values 1000 and 2200 s\/mm<jats:sup>2<\/jats:sup> at 3.0T MR. Fractional anisotropy (FA), apparent diffusion coefficient (ADC), radial diffusivity (eigenvalues \u03bb<jats:sub>1<\/jats:sub>, \u03bb<jats:sub>2<\/jats:sub>), and axial diffusivity (eigenvalue \u03bb<jats:sub>3<\/jats:sub>) were measured for the ipsilateral and contralateral corona radiata.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean FA was significantly lower for the ipsilateral than contralateral corona radiata with high <jats:italic>b<\/jats:italic> value, 2200 s\/mm<jats:sup>2<\/jats:sup>, and ipsilateral corona radiata with conventional low <jats:italic>b<\/jats:italic> value, 1000 s\/mm<jats:sup>2<\/jats:sup> (all <jats:italic>P<\/jats:italic> &lt; 0.01). Mean ADC, \u03bb<jats:sub>1<\/jats:sub>, \u03bb<jats:sub>2<\/jats:sub>, and \u03bb<jats:sub>3<\/jats:sub> were significantly higher for the ipsilateral than contralateral corona radiata with high <jats:italic>b<\/jats:italic> value (all <jats:italic>P<\/jats:italic> &lt; 0.05) but not for ipsilateral than contralateral corona radiata with low <jats:italic>b<\/jats:italic> value (<jats:italic>P<\/jats:italic> &gt; 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>DTI with a high <jats:italic>b<\/jats:italic> value detects diffusion changes in NAWM in patients with unilateral, severe stenosis, or occlusion of the MCA not seen with conventional <jats:italic>b<\/jats:italic> value or conventional MRI contrasts. <jats:bold>J. Magn. Reson. Imaging 2013;38:650\u2013654. \u00a9 2012 Wiley Periodicals, Inc.<\/jats:bold><\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.24004","type":"journal-article","created":{"date-parts":[[2013,5,6]],"date-time":"2013-05-06T20:47:25Z","timestamp":1367873245000},"page":"650-654","source":"Crossref","is-referenced-by-count":4,"title":["Diffusion tensor imaging of normal\u2010appearing white matter in unilateral cerebral arterial occlusive disease"],"prefix":"10.1002","volume":"38","author":[{"given":"Xiangshui","family":"Meng","sequence":"first","affiliation":[{"name":"Department of Radiology Qi Lu Hospital of Shandong University Jinan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Radiology Qi Lu Hospital of Shandong University Jinan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinwen","family":"Hou","sequence":"additional","affiliation":[{"name":"Department of 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