{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T01:43:47Z","timestamp":1792115027571,"version":"4.4.0"},"reference-count":34,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,4,10]],"date-time":"2013-04-10T00:00:00Z","timestamp":1365552000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>To investigate the differences in the fiber architecture and related diffusion tensor imaging (DTI) parameters among different uterine layers of the normal human uterus in vivo at 3 Tesla (T).<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>DTI of the uterus was performed for nine healthy women of reproductive age on a 3T scanner. A volume of interest (VOI) was drawn for the outer myometrium (OM), junctional zone (JZ), and endometrium (EM). Apparent diffusion coefficient (ADC), fractional anisotropy (FA), and maximum fiber length were compared using paired Student's t\u2010tests. Fibers were classified into four groups and were visually evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>ADC (\u00d710<jats:sup>\u22123<\/jats:sup> mm<jats:sup>2<\/jats:sup>\/s) was highest for OM (1.12), followed by EM (0.97) and JZ (0.83) (OM versus JZ, <jats:italic>P<\/jats:italic> &lt; 0.0001; JZ versus EM, <jats:italic>P<\/jats:italic> = 0.0001; OM versus EM, <jats:italic>P<\/jats:italic> = 0.0057). FA was highest for JZ (0.297), followed by OM (0.257) and EM (0.186) (OM versus JZ, <jats:italic>P<\/jats:italic> = 0.0002; JZ versus EM, <jats:italic>P<\/jats:italic> &lt; 0.0001; OM versus EM, <jats:italic>P<\/jats:italic> &lt; 0.0001). Fibers were longest in OM (42.0 mm), followed by JZ (34.2 mm) and EM (20.0 mm). Circularly oriented fibers were observed in 69% in OM and in 70% in JZ.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>DTI of the uterus in vivo revealed layer\u2010wise differences in the microstructure of the uterus. J. Magn. Reson. Imaging 2013;38:1494\u20131500. \u00a9 2013 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.24114","type":"journal-article","created":{"date-parts":[[2013,4,10]],"date-time":"2013-04-10T19:38:27Z","timestamp":1365622707000},"page":"1494-1500","source":"Crossref","is-referenced-by-count":33,"title":["Diffusion tensor imaging (DTI) of the normal human uterus in vivo at 3 tesla: Comparison of DTI parameters in the different uterine layers"],"prefix":"10.1002","volume":"38","author":[{"given":"Koji","family":"Fujimoto","sequence":"first","affiliation":[{"name":"Department of Diagnostic Imaging and Nuclear Medicine Kyoto University Graduate School of Medicine Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aki","family":"Kido","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging and Nuclear Medicine Kyoto University Graduate School of Medicine Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomohisa","family":"Okada","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging and Nuclear Medicine Kyoto University Graduate School of Medicine Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masato","family":"Uchikoshi","sequence":"additional","affiliation":[{"name":"Siemens Japan K.K. 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