{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T02:20:49Z","timestamp":1790821249774,"version":"4.1.0"},"reference-count":40,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,9,23]],"date-time":"2013-09-23T00:00:00Z","timestamp":1379894400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>To evaluate the usefulness of magnetic resonance elastography (MRE) as a noninvasive tool for predicting esophageal varices and identifying high\u2010risk varices.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>In all, 126 patients with liver cirrhosis, and who underwent both MRI including MRE of the liver as well as upper gastrointestinal endoscopy for variceal screening within 1 month before or after the MRI, were included in this study. The relationship between the liver stiffness values measured by MRE and the degree of esophageal varices was assessed using Spearman's correlation analysis. In addition, the diagnostic performance of MRE for predicting the presence of varices or high\u2010risk varices (grade \u2265II) was evaluated using the receiver\u2010operating characteristics (ROC) curves.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean stiffness values of liver parenchyma measured on MRE were well correlated with the grade of esophageal varices (<jats:italic>r<\/jats:italic>\u2009=\u20090.63). In addition, the MRE\u2010based liver stiffness values were significantly lower in the lower\u2010risk group than in the higher\u2010risk group (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001). The area under the ROC curve values of MRE for predicting the presence of varices or high\u2010risk varices (grade \u2265II) were 0.859 and 0.810, respectively. Using a liver stiffness cutoff value of 5.803 kPa, the sensitivity, specificity, positive predictive value, and negative predictive value for predicting high\u2010grade (\u2265II) esophageal varices were 96%, 60%, 36%, and 98%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The MRE\u2010based liver stiffness value may be useful for noninvasively predicting esophageal varices and identifying high\u2010risk varices in cirrhotic patients. <jats:bold>J. Magn. Reson. Imaging 2014;39:559\u2013566<\/jats:bold>. \u00a9 <jats:bold>2013 Wiley Periodicals, Inc<\/jats:bold>.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.24186","type":"journal-article","created":{"date-parts":[[2013,10,12]],"date-time":"2013-10-12T00:59:05Z","timestamp":1381539545000},"page":"559-566","source":"Crossref","is-referenced-by-count":36,"title":["Usefulness of MR elastography for predicting esophageal varices in cirrhotic patients"],"prefix":"10.1002","volume":"39","author":[{"given":"Hye Young","family":"Sun","sequence":"first","affiliation":[{"name":"Department of Radiology Seoul National University College of Medicine Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeong Min","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Radiology Seoul National University College of Medicine Seoul Korea"},{"name":"Institute of Radiation Medicine Seoul National University College of Medicine Seoul 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