{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T15:56:53Z","timestamp":1726156613844},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,5,30]],"date-time":"2013-05-30T00:00:00Z","timestamp":1369872000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>To assess low\u2010dose morphine for distension and improved visualization of intrahepatic bile ducts on T1 MR cholangiography (MRC) in preoperative imaging of potential liver donors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Sixty\u2010nine consecutive potential living related liver donors (mean age, 39 years; age range, 20 to 59 years) referred for pre\u2010transplant MRI evaluation were evaluated without (n\u2009=\u200930) or with (n\u2009=\u200939) intravenous morphine injection (0.04 mg\/kg). Morphine was injected pre\u2010MRI while establishing intravenous access to allow \u223c1 h for biliary distension before T1 MRC. Three radiologists reviewed intrahepatic biliary branch order visualization, common bile duct (CBD) diameter, and overall image quality. In 25 patients undergoing liver donation surgery, T1 MRC findings were correlated with intraoperative findings. This retrospective study was approved by the institutional review board.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Biliary visualization was improved post\u2010morphine administration with biliary duct branch order visualization score of 3.2 and 3.3 at 45 and 60 min, respectively, compared with 2.7 without morphine (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.002); CBD diameter measured 5.3 and 5.5 versus 4.1 mm (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.005), and overall image quality score was 2.4 and 2.6 versus 1.8 (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0006). Operative notes confirmed T1 MRC findings in 6\/11 donors without morphine and 14\/14 donors with morphine.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Intravenous low\u2010dose morphine distends and improves visualization of bile ducts on T1 gadoxetate MRC. <jats:bold>J. Magn. Reson. Imaging 2014;39:584\u2013589<\/jats:bold>. \u00a9 <jats:bold>2013 Wiley Periodicals, Inc<\/jats:bold>.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.24188","type":"journal-article","created":{"date-parts":[[2013,5,30]],"date-time":"2013-05-30T17:36:53Z","timestamp":1369935413000},"page":"584-589","source":"Crossref","is-referenced-by-count":4,"title":["Morphine three\u2010dimensional T1 gadoxetate MR cholangiography of potential living related liver donors"],"prefix":"10.1002","volume":"39","author":[{"given":"Mukta D.","family":"Agrawal","sequence":"first","affiliation":[{"name":"Department of Radiology Weill Cornell Medical College &amp; New York Presbyterian Hospital New York USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin W.","family":"Mennitt","sequence":"additional","affiliation":[{"name":"Department of Radiology Weill Cornell Medical College &amp; New York Presbyterian Hospital New York USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Honglei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Radiology Weill Cornell Medical College &amp; New York Presbyterian Hospital New York USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Samstein","sequence":"additional","affiliation":[{"name":"Department of Liver Transplantation Surgery Columbia University of Physicians and Surgeons New York USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoaki","family":"Kato","sequence":"additional","affiliation":[{"name":"Department of Liver Transplantation Surgery Columbia University of Physicians and Surgeons New York USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean C.","family":"Emond","sequence":"additional","affiliation":[{"name":"Department of Liver Transplantation Surgery Columbia University of Physicians and Surgeons New York USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvina P.","family":"Dutruel","sequence":"additional","affiliation":[{"name":"Department of Radiology Weill Cornell Medical College &amp; New York Presbyterian Hospital New York USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nanda Deepa","family":"Thimmappa","sequence":"additional","affiliation":[{"name":"Department of Radiology Weill Cornell Medical College &amp; New York Presbyterian Hospital New York USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin R.","family":"Prince","sequence":"additional","affiliation":[{"name":"Department of Radiology Columbia University of Physicians and Surgeons New York USA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,5,30]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"337","article-title":"Variations of the intrahepatic bile ducts: application in living related liver transplantation and splitting liver transplantation","volume":"11","author":"Cheng YF","year":"1997","journal-title":"Clin Transplant"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiographics.14.5.7991810"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s005340070007"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.177.2.1770389"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200006150-00034"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200206270-00008"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra011629"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-2980.2008.00339.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.176.6.1761475"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.09.3010"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21789"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiographics.22.3.g02ma20477"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.10.4392"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.23713"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.23683"},{"key":"e_1_2_6_17_1","article-title":"Improved hepatic arterial phase MRI with 3\u2010second temporal resolution","author":"Agrawal MD","year":"2012","journal-title":"J Magn Reson Imaging"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1018170"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2473070964"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(87)90019-1"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.243035087"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-005-0155-5"}],"container-title":["Journal of Magnetic Resonance Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmri.24188","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmri.24188","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T05:55:37Z","timestamp":1696398937000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmri.24188"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5,30]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["10.1002\/jmri.24188"],"URL":"https:\/\/doi.org\/10.1002\/jmri.24188","archive":["Portico"],"relation":{},"ISSN":["1053-1807","1522-2586"],"issn-type":[{"value":"1053-1807","type":"print"},{"value":"1522-2586","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,5,30]]}}}