{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T05:53:39Z","timestamp":1780638819046,"version":"3.54.1"},"reference-count":36,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,9,30]],"date-time":"2013-09-30T00:00:00Z","timestamp":1380499200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>To evaluate the MRI findings of renal cell carcinoma (RCC), including findings on diffusion\u2010weighted images (DWIs) and chemical shift images (CSIs), in patients with acquired cystic disease of the kidney (ACDK) in relation to the histopathologic findings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Two radiologists retrospectively reviewed the MRI findings of 10 RCCs in seven consecutive patients with ACDK. They evaluated the signal intensities (SIs) and signal homogeneity of the lesions on T2\u2010weighted images, DWIs, and T1\u2010weighted images. Thereafter, they evaluated the cytoplasmic fat in the lesions by CSIs. After image analyses, the MRI findings were correlated with the histopathologic findings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The RCCs tended to show heterogeneous high SIs on T2\u2010weighted images and DWIs. The high SIs on DWIs were mainly attributable to the viable parts, and the heterogeneity was due to the various SIs arising from the intratumoral degenerative components. Unlike the reported findings for hemorrhagic cysts, the RCCs did not show homogeneous high SIs or fluid\u2010iron levels on T1\u2010weighted images. The four lesions, in which the presence of cytoplasmic fat was suggested on CSIs, were clear cell RCCs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The MRI findings, including findings on DWIs and CSIs, well reflected the histopathologic findings of RCC in patients with ACDK. <jats:bold>J. Magn. Reson. Imaging 2014;39:924\u2013930.<\/jats:bold> \u00a9 <jats:bold>2013 Wiley Periodicals, Inc.<\/jats:bold><\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.24226","type":"journal-article","created":{"date-parts":[[2013,10,12]],"date-time":"2013-10-12T01:39:35Z","timestamp":1381541975000},"page":"924-930","source":"Crossref","is-referenced-by-count":8,"title":["Renal cell carcinoma in patients with acquired cystic disease of the kidney: Assessment using a combination of T2\u2010weighted, diffusion\u2010weighted, and chemical\u2010shift MRI without the use of contrast material"],"prefix":"10.1002","volume":"39","author":[{"given":"Hirotaka","family":"Akita","sequence":"first","affiliation":[{"name":"Department of Diagnostic Radiology Keio University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Jinzaki","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology Keio University School of Medicine Tokyo 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