{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T14:25:36Z","timestamp":1791037536972,"version":"4.1.0"},"reference-count":34,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,11,15]],"date-time":"2013-11-15T00:00:00Z","timestamp":1384473600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>To evaluate muscle perfusion in patients with peripheral arterial occlusive disease (PAOD) before and after percutaneous transluminal angioplasty (PTA) of the limb by means of MR arterial spin labeling (ASL) perfusion measurements during reactive hyperemia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Ten patients with symptomatic PAOD affecting the iliac or femoral vessels were investigated before and after PTA. A pseudo\u2010continuous arterial spin labeling (PCASL) MR technique was applied. Perfusion was measured in soleus and tibialis anterior muscle during reactive hyperemia. Key parameters such as mean perfusion value (P<jats:sub>hyp<\/jats:sub>), time\u2010to\u2010peak (TTP) and duration of hyperemia (T<jats:sub>hyp<\/jats:sub>) describing the perfusion signal curve were examined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Between baseline and post\u2010PTA, P<jats:sub>hyp<\/jats:sub> increased in both muscle groups. At the same time, TTP and T<jats:sub>hyp<\/jats:sub> decreased in both muscle groups. At the same time the clinically assessed ankle brachial index (ABI) increased from 0.56\u2009\u00b1\u20090.10 to 0.83\u2009\u00b1\u20090.15. The impaired pain\u2010free walking distance improved in all patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>PCASL MRI can detect changes of the key perfusion parameters P<jats:sub>hyp<\/jats:sub>, TTP, and T<jats:sub>hyp<\/jats:sub> after successful PTA of the calf muscles during reactive hyperemia and seems to be a promising tool for monitoring of interventional treatments. <jats:bold>J. Magn. Reson. Imaging 2014;40:980\u2013987<\/jats:bold>. \u00a9 <jats:bold>2013 Wiley Periodicals, Inc<\/jats:bold>.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.24463","type":"journal-article","created":{"date-parts":[[2013,11,15]],"date-time":"2013-11-15T22:11:39Z","timestamp":1384553499000},"page":"980-987","source":"Crossref","is-referenced-by-count":48,"title":["Perfusion measurements of the calf in patients with peripheral arterial occlusive disease before and after percutaneous transluminal angioplasty using Mr arterial spin labeling"],"prefix":"10.1002","volume":"40","author":[{"given":"Gerd","family":"Gr\u00f6zinger","sequence":"first","affiliation":[{"name":"Division of Diagnostic Radiology Department of Diagnostic and Interventional Radiology University of T\u00fcbingen T\u00fcbingen Germany"},{"name":"Section on Experimental Radiology Department of Diagnostic and Interventional Radiology University of T\u00fcbingen T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolf","family":"Pohmann","sequence":"additional","affiliation":[{"name":"Max Planck Institute for Biological Cybernetics Magnetic Resonance Center T\u00fcbingen T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fritz","family":"Schick","sequence":"additional","affiliation":[{"name":"Section on Experimental Radiology Department of Diagnostic and Interventional Radiology University of T\u00fcbingen T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich","family":"Grosse","sequence":"additional","affiliation":[{"name":"Division of Diagnostic Radiology Department of Diagnostic and Interventional Radiology University of T\u00fcbingen T\u00fcbingen Germany"},{"name":"Section on Experimental Radiology Department of Diagnostic and Interventional Radiology University of T\u00fcbingen T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roland","family":"Syha","sequence":"additional","affiliation":[{"name":"Division of Diagnostic Radiology Department of Diagnostic and Interventional Radiology University of T\u00fcbingen T\u00fcbingen Germany"},{"name":"Section on Experimental Radiology Department of Diagnostic and Interventional Radiology University of T\u00fcbingen T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"Brechtel","sequence":"additional","affiliation":[{"name":"Division of Diagnostic Radiology Department of Diagnostic and Interventional Radiology University of T\u00fcbingen T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kilian","family":"Rittig","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Division of Endocrinology Diabetology Angiology Nephrology and Clinical Chemistry University of T\u00fcbingen T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petros","family":"Martirosian","sequence":"additional","affiliation":[{"name":"Section on Experimental Radiology Department of Diagnostic and Interventional Radiology University of T\u00fcbingen T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,11,15]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9150(03)00204-1"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000137913.26087.F0"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.11.045"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365518009092656"},{"key":"e_1_2_5_6_1","first-page":"81","article-title":"Inter\u2010society consensus for the management of peripheral arterial disease","volume":"26","author":"Norgren L","year":"2007","journal-title":"Int Angiol"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-005-0111-3"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-60-719-1083"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.214.2.r00fe42325"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004210000267"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/RLI.0b013e3182183a77"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.4330\/wjc.v3.i12.377"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.20535"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.605717"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-008-1168-6"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/RLI.0b013e3181b248f9"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.1081"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.1880080516"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/RLI.0b013e3181f2bfb8"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.21790"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.03.033"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2010.09.020"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2412050701"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.22243"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.01399.2007"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.1985.9"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.91.1.33"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1993.sp019614"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.2000.279.4.H1715"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.27.4.520"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.1114\/1.241"},{"key":"e_1_2_5_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910400303"},{"key":"e_1_2_5_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2012.03.022"},{"key":"e_1_2_5_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2006.12.037"},{"key":"e_1_2_5_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.20737"}],"container-title":["Journal of Magnetic Resonance Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmri.24463","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmri.24463","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T12:55:58Z","timestamp":1696337758000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmri.24463"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11,15]]},"references-count":34,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,10]]}},"alternative-id":["10.1002\/jmri.24463"],"URL":"https:\/\/doi.org\/10.1002\/jmri.24463","archive":["Portico"],"relation":{},"ISSN":["1053-1807","1522-2586"],"issn-type":[{"value":"1053-1807","type":"print"},{"value":"1522-2586","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11,15]]}}}