{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,16]],"date-time":"2026-08-16T05:33:02Z","timestamp":1786858382046,"version":"build-2736575974"},"reference-count":33,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,8,27]],"date-time":"2014-08-27T00:00:00Z","timestamp":1409097600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>To estimate the local thermal conductivity of uterine fibroid in vivo at a high temperature range (60\u201380\u00b0C) typically encountered in magnetic resonance imaging\u2010guided high\u2010intensity focused ultrasound (MRgHIFU) surgery. The thermal conductivity of uterine fibroids in vivo is unknown and knowledge about tissue thermal conductivity may aid in effective delivery of thermal energy for ablation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>All subjects (nine women) provided written informed consent to participate in this Institutional Review Board\u2010approved study. A total of 10 fibroids were treated using MRgHIFU surgery with real\u2010time temperature monitoring during both heating and cooling periods. The local thermal conductivity was determined by analyzing the spatiotemporal spread of temperature during the cooling period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The thermal conductivity of MRgHIFU\u2010treated uterine fibroids was 0.47 \u00b1 0.07 W\u00b7m<jats:sup>\u20131<\/jats:sup>\u00b7K<jats:sup>\u20131<\/jats:sup> (range: 0.25\u223c0.67 W\u00b7m<jats:sup>\u20131<\/jats:sup>\u00b7K<jats:sup>\u20131<\/jats:sup>) which is slightly lower than the reported value for skeletal muscle at temperatures of &lt;40\u00b0C (0.52 to 0.62 W\u00b7m<jats:sup>\u20131<\/jats:sup>\u00b7K<jats:sup>\u20131<\/jats:sup>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>It is possible to estimate the thermal conductivity of uterine fibroids in vivo from the spatiotemporal spread of temperature around the HIFU focus during the cooling period. <jats:bold>J. Magn. Reson. Imaging 2015;41:1654\u20131661<\/jats:bold>. \u00a9 <jats:bold>2014 Wiley Periodicals, Inc<\/jats:bold>.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.24724","type":"journal-article","created":{"date-parts":[[2014,8,27]],"date-time":"2014-08-27T10:37:04Z","timestamp":1409135824000},"page":"1654-1661","source":"Crossref","is-referenced-by-count":12,"title":["Noninvasive, in vivo determination of uterine fibroid thermal conductivity in MRI\u2010guided high intensity focused ultrasound therapy"],"prefix":"10.1002","volume":"41","author":[{"given":"Jiming","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology CHI St. Luke's Health Houston Texas USA"},{"name":"Department of Physics and Texas Center for Superconductivity at University of Houston Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Fischer","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and 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