{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T22:17:55Z","timestamp":1777414675477,"version":"3.51.4"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,3,30]],"date-time":"2015-03-30T00:00:00Z","timestamp":1427673600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>To compare the diagnostic accuracy of routine magnetic resonance imaging (MRI) (<jats:italic>T<\/jats:italic><jats:sub>1<\/jats:sub>WI and <jats:italic>T<\/jats:italic><jats:sub>2<\/jats:sub>WI), diffusion\u2010weighted MRI (DWI), and DCE\u2010MRI (dynamic contrast\u2010enhanced MRI) at 3.0T for differentiation of cervical cancer and benign cervical lesions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>A cohort of 75 cervical cancer patients, 26 cervical leiomyoma patients, 22 patients with cervical polyps consecutively underwent pelvic MRI scanning on a 3T MR unit. Two radiologists independently evaluated images at three imaging settings; routine MRI alone, DWI combined with routine MRI (DWI+routine MRI), and DCE\u2010MRI. The apparent diffusion coefficients (ADCs) were calculated from b 0, 600 s\/mm<jats:sup>2<\/jats:sup> and b 0, 1000 s\/mm<jats:sup>2<\/jats:sup>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>DWI+routine MRI was significantly better than routine MRI and obtained high accuracy (0.95); the diagnostic performance was not significantly different between DWI+routine MRI and DCE\u2010MRI. Reader agreement was excellent for both DWI+routine MRI (\u03ba, 0.90) and DCE\u2010MRI (\u03ba, 0.92). The ADCs of cervical cancer were significantly lower than those of benign cervical lesions at both ADC maps (<jats:italic>P<\/jats:italic>\u2009=\u20090.0001). The diagnostic accuracy was not different at both ADC maps (<jats:italic>P<\/jats:italic>\u2009=\u20090.375).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>For differentiation of cervical cancer and benign cervical lesions, unenhanced MRI with combined diffusion\u2010weighted and routine MRI (DWI+routine MRI) at 3T can provide accurate information and may be preferable to DCE. J. Magn. Reson. Imaging 2015. J. Magn. Reson. Imaging 2015;42:1094\u20131099.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.24894","type":"journal-article","created":{"date-parts":[[2015,3,30]],"date-time":"2015-03-30T14:06:43Z","timestamp":1427724403000},"page":"1094-1099","source":"Crossref","is-referenced-by-count":23,"title":["Diagnostic accuracy of diffusion\u2010weighted MRI for differentiation of cervical cancer and benign cervical lesions at 3.0T: Comparison with routine MRI and dynamic contrast\u2010enhanced MRI"],"prefix":"10.1002","volume":"42","author":[{"given":"Fei","family":"Kuang","sequence":"first","affiliation":[{"name":"Department of Medical Imaging 174th Hospital of Chinese PLA Xiamen Fujian Province P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiping","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging 174th Hospital of Chinese PLA Xiamen Fujian Province P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huili","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging 174th Hospital of Chinese PLA Xiamen Fujian Province P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Pathematology The 174th Hospital of Chinese PLA Xiamen Fujian Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,3,30]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.180.6.1801621"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-005-2804-z"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.06.1196"},{"key":"e_1_2_5_5_1","first-page":"947","article-title":"Endometrial cancer of the uterus. American College of Radiology. 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