{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T13:56:32Z","timestamp":1768744592839,"version":"3.49.0"},"reference-count":40,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,1,23]],"date-time":"2016-01-23T00:00:00Z","timestamp":1453507200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Development Foundation of Region Sk\u00e5ne"},{"name":"Dir Albert P\u00e5hlsson's Foundation."}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>To study the feasibility and to gauge the potential clinical impact of quantifying small bowel motility using magnetic resonance imaging (MRI) in a larger population with a spectra of gastrointestinal conditions with impaired small bowel motility.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Data were gathered retrospectively from a cohort of 127 patients undergoing MR enterography (1.5 Tesla) in 2011. Cine motility sequences were processed with validated motility analysis software and a parametric motility map was generated. Regions of interests were drawn in the jejunum, ileum, and terminal ileum, and Jacobian standard deviation mean motility index' score (MIS) was calculated. Patients were divided into Crohn's disease (CD), ulcerative colitis, irritable bowel syndrome, and healthy subjects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In CD, terminal ileum motility was lower in comparison to healthy subjects (mean difference: \u20100.1052 arbitrary units, 95% confidence interval: \u20100.1981\u2013\u20100.0122, <jats:italic>P<\/jats:italic>\u2009=\u20090.018). Subgrouping of CD showed that the difference was recognized in patients with disease limited to the small bowel (mean difference: \u20100.1440 arbitrary units, 95% confidence interval: \u22120.2491\u2013\u20100.0389, <jats:italic>P<\/jats:italic>\u2009=\u20090.002). Visible dysmotility of terminal ileum on MRI reflected a reduced MIS compared with normal motility (0.22\u2009\u00b1\u20090.09 and 0.33\u2009\u00b1\u20090.15 arbitrary units, respectively, <jats:italic>P<\/jats:italic>\u2009=\u20090.043). Motility correlated negatively between ileum and age (<jats:italic>P<\/jats:italic>\u2009=\u20090.021), and between terminal ileum and C\u2010reactive protein in ulcerative colitis (<jats:italic>P<\/jats:italic>\u2009=\u20090.031).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Motility quantitation revealed a significant difference in motility of terminal ileum in patients with small bowel CD compared with healthy subjects, concording with visible dysmotility and inflammatory changes. J. Magn. Reson. Imaging 2016;44:277\u2013287.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.25166","type":"journal-article","created":{"date-parts":[[2016,1,23]],"date-time":"2016-01-23T12:39:00Z","timestamp":1453552740000},"page":"277-287","source":"Crossref","is-referenced-by-count":30,"title":["Computational postprocessing quantification of small bowel motility using magnetic resonance images in clinical practice: An initial experience"],"prefix":"10.1002","volume":"44","author":[{"given":"Andr\u00e9","family":"\u00c5kerman","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences, Division of Internal Medicine Sk\u00e5ne University Hospital, Malm\u00f6, Lund University  Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sven","family":"M\u00e5nsson","sequence":"additional","affiliation":[{"name":"Medical Radiation Physics, Department of Translational Medicine Lund University, Sk\u00e5ne University Hospital Malm\u00f6 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