{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T17:24:13Z","timestamp":1782494653458,"version":"3.54.5"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,3,28]],"date-time":"2016-03-28T00:00:00Z","timestamp":1459123200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>To prospectively determine the efficacy and safety of magnetic resonance imaging (MRI)\u2010guided celiac plexus neurolysis (CPN) for pancreatic cancer pain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>In all, 39 patients with pancreatic cancer underwent 0.23T MRI\u2010guided CPN with ethanol via the posterior approach. The pain relief, the opioid intake, and pain interference with appetite, sleep, and communication in patients were assessed after CPN during a 4\u2010month follow\u2010up period. The complications were also evaluated during or after CPN.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>CPN procedures were successfully completed for all patients. Minor complications included diarrhea (9 of 39; 23.1%), orthostatic hypotension (14 of 39; 35.9%), and local backache (20 of 39; 51.3%). No major complication occurred. Pain relief was observed in 36 (92.3%), in 15 (40.5%), and in 11 (35.5%) patients at 1\u2010, 2\u2010, and 3\u2010month visits, respectively. The median duration of pain relief was 2.9 months (95% confidence interval [CI], 2.4\u20133.4). The opioid intake significantly decreased at the 1\u2010, 2\u2010, and 3\u2010month visits (<jats:italic>P<\/jats:italic> &lt; 0.001, &lt; 0.001, = 0.001 respectively), and there was significant improvement in sleep at the 1\u2010, 2\u2010, and 3\u2010month visits (<jats:italic>P<\/jats:italic> &lt; 0.001, &lt; 0.001, = 0.001 respectively), and appetite and communication were significantly improved at the 1\u2010 and 2\u2010month visits (all <jats:italic>P<\/jats:italic> &lt; 0.001); all compared with baseline.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>MRI\u2010guided CPN appears to be an effective and minimally invasive procedure for palliative pain management of pancreatic cancer. J. MAGN. RESON. IMAGING 2016;44:923\u2013928.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.25246","type":"journal-article","created":{"date-parts":[[2016,3,28]],"date-time":"2016-03-28T14:08:39Z","timestamp":1459174119000},"page":"923-928","source":"Crossref","is-referenced-by-count":19,"title":["MRI\u2010guided celiac plexus neurolysis for pancreatic cancer pain: Efficacy and safety"],"prefix":"10.1002","volume":"44","author":[{"given":"Shangang","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Medical Oncology Fourth People's Hospital of Zibo City The affiliated Hospital of Shandong Cancer Hospital and Institute Zibo China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiwei","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Fourth People's Hospital of Zibo City The affiliated Hospital of Shandong Cancer Hospital and Institute Zibo 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