{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T02:25:51Z","timestamp":1767925551864,"version":"3.49.0"},"reference-count":21,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,3,16]],"date-time":"2017-03-16T00:00:00Z","timestamp":1489622400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>To compare a faster diagonal diffusion\u2010weighted imaging (d\u2010DWI) to conventional three\u2010scan trace DWI (t\u2010DWI) acquisition for prostate magnetic resonance imaging (MRI) in terms of image quality, tumor detection\/conspicuity, Prostate Imaging Reporting and Data System (PI\u2010RADS) characterization, quantitative estimated signal\u2010to\u2010noise ratio (eSNR), and apparent diffusion coefficient (ADC) measurement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods<\/jats:title><jats:p>A total of 34 consecutive men with suspected prostate cancer (PCa) who underwent 3T MRI of the prostate were assessed. MRI included t\u2010DWI and d\u2010DWI (using b\u2010values of 50, 1000, and 1600 s\/mm<jats:sup>2<\/jats:sup>, number of averages 1\/5\/10 for t\u2010DWI vs. 2\/8\/14 for d\u2010DWI, acquisition time 6:21\u2009min vs. 4:17\u2009min, respectively). Two independent observers evaluated image quality, including image sharpness, anatomic distortion, and artifacts on a 5\u2010point scale (1\u20135) and assessed tumor detection, conspicuity, and PI\u2010RADS classification with both DWI sequences. eSNR and ADC were measured in the peripheral zone (PZ), transitional zone (TZ), and detected tumors. Data was compared using paired Wilcoxon signed rank tests and McNemar test. Coefficients of variations (CV) between ADC obtained with both sequences were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Significantly fewer artifacts were observed on d\u2010DWI at b 1600 for observer 2 (<jats:italic>P<\/jats:italic> &lt; 0.01), while the other image quality scores were equivalent for both sequences. eSNR was lower with d\u2010DWI vs. t\u2010DWI in PZ and TZ for b 1000 (<jats:italic>P<\/jats:italic> &lt; 0.01 and <jats:italic>P<\/jats:italic>\u2009=\u20090.03, respectively) and b 1600 (<jats:italic>P<\/jats:italic> &lt; 0.01 for both). ADC reproducibility between sequences was excellent (CV &lt;10%). No significant differences were found for tumor detection (<jats:italic>P<\/jats:italic> \u2265 0.25), conspicuity (<jats:italic>P<\/jats:italic> \u2265 0.12), or PI\u2010RADS classification (<jats:italic>P<\/jats:italic> \u2265 0.10).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>d\u2010DWI can provide a substantial reduction in acquisition time (\u223c30%) while maintaining equivalent tumor detection, PI\u2010RADS score, image quality, and ADC values.<\/jats:p><jats:p><jats:bold>Level of Evidence:<\/jats:bold> 3<\/jats:p><jats:p><jats:bold>Technical Efficacy:<\/jats:bold> Stage 2<\/jats:p><jats:p>J. Magn. Reson. Imaging 2017;46:1767\u20131775.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.25705","type":"journal-article","created":{"date-parts":[[2017,3,16]],"date-time":"2017-03-16T18:21:17Z","timestamp":1489688477000},"page":"1767-1775","source":"Crossref","is-referenced-by-count":11,"title":["DWI of the prostate: Comparison of a faster diagonal acquisition to standard three\u2010scan trace acquisition"],"prefix":"10.1002","volume":"46","author":[{"given":"Idoia","family":"Corcuera\u2010Solano","sequence":"first","affiliation":[{"name":"Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai New York New York USA"},{"name":"Department of Radiology Icahn School of Medicine at Mount Sinai New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathilde","family":"Wagner","sequence":"additional","affiliation":[{"name":"Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai New York New York 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USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alto","family":"Stemmer","sequence":"additional","affiliation":[{"name":"Siemens AG, Medical Solutions, Magnetic Resonance Erlangen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ardeshir","family":"Rastinehad","sequence":"additional","affiliation":[{"name":"Department of Urology Icahn School of Medicine at Mount Sinai New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashutosh","family":"Tewari","sequence":"additional","affiliation":[{"name":"Department of Urology Icahn School of Medicine at Mount Sinai New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bachir","family":"Taouli","sequence":"additional","affiliation":[{"name":"Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai New York New York USA"},{"name":"Department of Radiology Icahn School of Medicine at Mount Sinai New York New 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