{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T16:00:25Z","timestamp":1762444825172,"version":"3.40.5"},"reference-count":22,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,10,22]],"date-time":"2018-10-22T00:00:00Z","timestamp":1540166400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Previous studies have shown that abbreviated magnetic resonance imaging (aMRI) compares well to full\u2010protocol MRI (fpMRI) in breast cancer (BC) screening, with the potential advantage of a less costly and complex examination. To our knowledge, the role for aMRI in staging BC has been poorly investigated, especially in assessing additional disease (ie, additional lesions compared to the index one prompting the examination).<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To compare aMRI and fpMRI in detecting additional disease in BC staging.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study type<\/jats:title><jats:p>Retrospective monocentric cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>In all, 87 patients with 89 biopsy\u2010proven index lesions referred to staging fpMRI between January\u2013June 2016.<\/jats:p><\/jats:sec><jats:sec><jats:title>Field Strength\/Sequence<\/jats:title><jats:p>A 1.5T magnet using short tau inversion recovery (STIR) T<jats:sub>2<\/jats:sub>\u2010weighted imaging, echoplanar diffusion\u2010weighted imaging, and 3D fast long angle shot (FLASH) T<jats:sub>1<\/jats:sub>\u2010weighted imaging.<\/jats:p><\/jats:sec><jats:sec><jats:title>Assessment<\/jats:title><jats:p>During independent sessions, four readers with 1.5\u201320 years of experience in breast imaging, blinded to the pathological examination and previous imaging, assessed multifocal, multicentric, and contralateral additional lesions on fpMRI and aMRI (including precontrast T<jats:sub>1<\/jats:sub>\u2010weighted 3D FLASH sequence, first postcontrast subtracted T<jats:sub>1<\/jats:sub>\u2010weighted 3D FLASH sequence, and a transverse maximum intensity projection reconstruction).<\/jats:p><\/jats:sec><jats:sec><jats:title>Statistical Tests<\/jats:title><jats:p>We calculated the per\u2010lesion cancer detection rate (CDR), positive predictive value (PPV), and false discovery rate (FDR) for additional disease, assessing the significance of intrareader differences in CDR with the McNemar test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Pathological analysis found 36 additional lesions (multifocal, multicentric, and contralateral in 20, 15, and 1 cases, respectively). Readers' CDR was comparably high using aMRI (range 88.9\u201394.4%) or fpMRI (range 91.7\u201394.4%) (<jats:italic>P<\/jats:italic> &gt; 0.05). PPV and FDR of aMRI (ranges 76.2\u201384.6% and 15.4\u201323.8%, respectively), and fpMRI (ranges 76.7\u201382.9% and 17.2\u201323.3%, respectively) were comparable on an intrareader basis. Using aMRI, two out of four readers induced two false\u2010negative cases (one case each) with presumably limited impact on surgical planning (multifocal cancers &lt;1\u2009cm in size).<\/jats:p><\/jats:sec><jats:sec><jats:title>Data Conclusion<\/jats:title><jats:p>aMRI was comparable to fpMRI in staging additional BC.<\/jats:p><jats:p><jats:bold>Level of Evidence:<\/jats:bold> 3<\/jats:p><jats:p><jats:bold>Technical Efficacy:<\/jats:bold> Stage 2<\/jats:p><jats:p>J. Magn. Reson. Imaging 2019;49:e222\u2013e230.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.26339","type":"journal-article","created":{"date-parts":[[2018,10,23]],"date-time":"2018-10-23T06:39:50Z","timestamp":1540276790000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Comparison between an abbreviated and full MRI protocol for detecting additional disease when doing breast cancer staging"],"prefix":"10.1002","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0904-5147","authenticated-orcid":false,"given":"Rossano","family":"Girometti","sequence":"first","affiliation":[{"name":"Institute of Radiology, Department of Medicine University of Udine \u2013 \u201cS. Maria della Misericordia\u201d University Hospital  Udine Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriana","family":"Nitti","sequence":"additional","affiliation":[{"name":"Institute of Radiology, Department of Medicine University of Udine \u2013 \u201cS. Maria della Misericordia\u201d University Hospital  Udine Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Lorenzon","sequence":"additional","affiliation":[{"name":"Institute of Radiology, Department of Medicine University of Udine \u2013 \u201cS. Maria della Misericordia\u201d University Hospital  Udine Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franco","family":"Greco","sequence":"additional","affiliation":[{"name":"Institute of Radiology, Department of Medicine University of Udine \u2013 \u201cS. Maria della Misericordia\u201d University Hospital  Udine Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viviana","family":"Londero","sequence":"additional","affiliation":[{"name":"Institute of Radiology, Department of Medicine University of Udine \u2013 \u201cS. Maria della Misericordia\u201d University Hospital  Udine Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiara","family":"Zuiani","sequence":"additional","affiliation":[{"name":"Institute of Radiology, Department of Medicine University of Udine \u2013 \u201cS. Maria della Misericordia\u201d University Hospital  Udine Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,10,22]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2007.07.014"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.15.2108"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.21.5756"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2010.02.015"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.5306\/wjco.v5.i2.61"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00117-008-1665-2"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2012.03.002"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.5152\/dir.2018.16609"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.52.5386"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12282-016-0718-z"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.183.4.1831149"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2015.06.004"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-017-4264-y"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clbc.2016.02.008"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A4615"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2016.01.005"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2014.10.004"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2016.07.020"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clbc.2017.10.012"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-010-1326-9"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2014.10.023"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-009-1654-5"}],"container-title":["Journal of Magnetic Resonance Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmri.26339","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmri.26339","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jmri.26339","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmri.26339","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T11:23:14Z","timestamp":1694344994000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmri.26339"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,22]]},"references-count":22,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["10.1002\/jmri.26339"],"URL":"https:\/\/doi.org\/10.1002\/jmri.26339","archive":["Portico"],"relation":{},"ISSN":["1053-1807","1522-2586"],"issn-type":[{"type":"print","value":"1053-1807"},{"type":"electronic","value":"1522-2586"}],"subject":[],"published":{"date-parts":[[2018,10,22]]},"assertion":[{"value":"2018-07-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-10-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}