{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T18:47:56Z","timestamp":1793731676840,"version":"4.6.1"},"reference-count":34,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,1,13]],"date-time":"2019-01-13T00:00:00Z","timestamp":1547337600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Long acquisition times and motion sensitivity limit T<jats:sub>2<\/jats:sub> mapping in the abdomen. Accelerated mapping at 3 T may allow for quantitative assessment of diffuse pancreatic disease in patients during free\u2010breathing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To test the feasibility of respiratory\u2010triggered quantitative T<jats:sub>2<\/jats:sub> analysis in the pancreas and correlate T<jats:sub>2<\/jats:sub>\u2010values with age, body mass index, pancreatic location, main pancreatic duct dilatation, and underlying pathology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Type<\/jats:title><jats:p>Retrospective single\u2010center pilot study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>Eighty\u2010eight adults.<\/jats:p><\/jats:sec><jats:sec><jats:title>Field Strength\/Sequence<\/jats:title><jats:p>Ten\u2010fold accelerated multiecho\u2010spin\u2010echo 3 T MRI sequence to quantify T<jats:sub>2<\/jats:sub> at 3 T.<\/jats:p><\/jats:sec><jats:sec><jats:title>Assessment<\/jats:title><jats:p>Two radiologists independently delineated three regions of interest inside the pancreatic head, body, and tail for each acquisition. Means and standard deviations for T<jats:sub>2<\/jats:sub> values in these regions were determined. T<jats:sub>2<\/jats:sub>\u2010value variation with demographic data, intraparenchymal location, pancreatic duct dilation, and underlying pancreatic disease was assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Statistical Tests<\/jats:title><jats:p>Interreader reliability was determined by calculating the interclass coefficient (ICCs). T<jats:sub>2<\/jats:sub> values were compared for different pancreatic locations by analysis of variance (ANOVA). Interpatient associations between T<jats:sub>2<\/jats:sub> values and demographical, clinical, and radiological data were calculated (ANOVA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The accelerated T<jats:sub>2<\/jats:sub> mapping sequence was successfully performed in all participants (mean acquisition time, 2:48 \u00b1 0:43 min). Low T<jats:sub>2<\/jats:sub> value variability was observed across all patients (intersubject) (head: 60.2 \u00b1 8.3 msec, body: 63.9 \u00b1 11.5 msec, tail: 66.8 \u00b1 16.4 msec). Interreader agreement was good (ICC, 0.82, 95% confidence interval: 0.77\u20130.86). T<jats:sub>2<\/jats:sub>\u2010values differed significantly depending on age (<jats:italic>P<\/jats:italic> &lt; 0.001), location (<jats:italic>P<\/jats:italic> &lt; 0.001), main pancreatic duct dilatation (<jats:italic>P<\/jats:italic> &lt; 0.001), and diffuse pancreatic disease (<jats:italic>P<\/jats:italic> &lt; 0.03).<\/jats:p><\/jats:sec><jats:sec><jats:title>Data Conclusion<\/jats:title><jats:p>The feasibility of accelerated T<jats:sub>2<\/jats:sub> mapping at 3 T in moving abdominal organs was demonstrated in the pancreas, since T<jats:sub>2<\/jats:sub> values were stable and reproducible. In the pancreatic parenchyma, T<jats:sub>2<\/jats:sub>\u2010values were significantly dependent on demographic and clinical parameters.<\/jats:p><jats:p><jats:bold>Level of Evidence<\/jats:bold>: 4<\/jats:p><jats:p><jats:bold>Technical Efficacy<\/jats:bold>: Stage 1<\/jats:p><jats:p>J. Magn. Reson. Imaging 2019;50:410\u2013416.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.26612","type":"journal-article","created":{"date-parts":[[2019,1,14]],"date-time":"2019-01-14T07:36:45Z","timestamp":1547451405000},"page":"410-416","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Patient respiratory\u2010triggered quantitative T<sub>2<\/sub> mapping in the pancreas"],"prefix":"10.1002","volume":"50","author":[{"given":"Na\u00efk","family":"Vietti Violi","sequence":"first","affiliation":[{"name":"Department of Radiology University hospital (CHUV) and University of Lausanne (UNIL)  Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"Hilbert","sequence":"additional","affiliation":[{"name":"Department of Radiology University hospital (CHUV) and University of Lausanne (UNIL)  Lausanne Switzerland"},{"name":"Advanced Clinical Imaging Technology Siemens Healthcare  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