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Dixon cardiac MRF native T<jats:sub>1<\/jats:sub>, T<jats:sub>2<\/jats:sub>, FF, postcontrast T<jats:sub>1<\/jats:sub> and synthetic extracellular volume (ECV) maps were assessed in 19 patients in comparison to conventional sequences. Measurements in patients were performed in the septum and in late gadolinium enhanced (LGE) areas and assessed using mean value distributions, correlation, and Bland\u2013Altman plots. Image quality and diagnostic confidence were assessed by three experts using 5\u2010point scoring scales.<\/jats:p><\/jats:sec><jats:sec><jats:title>Statistical Tests<\/jats:title><jats:p>Paired Wilcoxon rank signed test and paired <jats:italic>t<\/jats:italic>\u2010tests were applied. Statistical significance was indicated by *(<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Dixon cardiac MRF showed good overall precision in phantom and in vivo. Septal average repeatability was ~23 msec for T<jats:sub>1<\/jats:sub>, ~2.2 msec for T<jats:sub>2<\/jats:sub>, and\u2009~1% for FF. Biases in healthy subjects\/patients were measured at +37 msec*\/+60 msec* and \u20138.8 msec*\/\u20138 msec* when compared to MOLLI and T<jats:sub>2<\/jats:sub>\u2010GRASE, respectively. No statistically significant differences in postcontrast T<jats:sub>1<\/jats:sub> (<jats:italic>P<\/jats:italic> = 0.17) and synthetic ECV (<jats:italic>P<\/jats:italic> = 0.19) measurements were observed in patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Data Conclusion<\/jats:title><jats:p>Dixon cardiac MRF attained good overall precision in phantom and healthy subjects, while providing coregistered T<jats:sub>1<\/jats:sub>, T<jats:sub>2<\/jats:sub>, and fat fraction maps in a single breath\u2010hold scan with similar or better image quality than conventional methods in patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>2.<\/jats:p><\/jats:sec><jats:sec><jats:title>Technical Efficacy Stage<\/jats:title><jats:p>2.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.27415","type":"journal-article","created":{"date-parts":[[2020,10,30]],"date-time":"2020-10-30T03:11:22Z","timestamp":1604027482000},"page":"1253-1265","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["<scp>T1<\/scp>, <scp>T2,<\/scp> and Fat Fraction Cardiac MR Fingerprinting: Preliminary Clinical Evaluation"],"prefix":"10.1002","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7854-4150","authenticated-orcid":false,"given":"Olivier","family":"Jaubert","sequence":"first","affiliation":[{"name":"School of Biomedical Engineering and Imaging Sciences, King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gastao","family":"Cruz","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering and Imaging Sciences, King's College London  London 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