{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T23:48:52Z","timestamp":1790380132344,"version":"4.1.0"},"reference-count":14,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,2,28]],"date-time":"2021-02-28T00:00:00Z","timestamp":1614470400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Prior imaging studies characterizing lumbar arachnoiditis have been based on small sample numbers and have reported inconsistent results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To review the different imaging patterns of lumbosacral arachnoiditis, their significance, and clinical implications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study type<\/jats:title><jats:p>Retrospective.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>A total of 96 patients (43 women; average age 61.3\u2009years) with imaging findings of arachnoiditis (postsurgical: <jats:italic>N<\/jats:italic>\u00a0=\u00a049; degenerative: <jats:italic>N<\/jats:italic>\u00a0=\u00a029; vertebral fracture: <jats:italic>N<\/jats:italic>\u00a0=\u00a06; epidural and subdural hemorrhage: <jats:italic>N<\/jats:italic>\u00a0=\u00a03, infectious: <jats:italic>N<\/jats:italic>=\u20091; other: <jats:italic>N<\/jats:italic>\u00a0=\u00a08) from January 2009 to April 2018.<\/jats:p><\/jats:sec><jats:sec><jats:title>Field strength\/Sequence<\/jats:title><jats:p>Sagittal and axial T2\u2010weighted Turbo Spin Echo at 1.5\u2009T and 3\u2009T.<\/jats:p><\/jats:sec><jats:sec><jats:title>Assessment<\/jats:title><jats:p>Chart review was performed to assess the cause of arachnoiditis, and imaging was reviewed by two musculoskeletal and three neurology radiologists, blinded to the clinical data and to each other's imaging interpretation. Previous classification included a three\u2010group system based on the appearance of the nerve roots on T2\u2010weighted images. A fourth group was added in our review as \u201cnonspecified\u201d and was proposed for indeterminate imaging findings that did not fall into the classical groups. The presence\/absence of synechiae\/fibrous bands that distort the nerve roots and of spinal canal stenosis was also assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Statistical tests<\/jats:title><jats:p>The kappa score was used to assess agreement between readers for both classification type and presence\/absence of synechiae.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Postsurgical (51%) and degenerative changes (30%) were the most common etiologies. About 7%\u201355% of arachnoiditis were classified as group 4. There was very poor classification agreement between readers (kappa score 0.051). There was also poor interreader agreement for determining the presence of synechiae (kappa 0.18) with, however, strong interreader agreement for the presence of synechia obtained between the most experienced readers (kappa 0.89).<\/jats:p><\/jats:sec><jats:sec><jats:title>Data Conclusion<\/jats:title><jats:p>This study demonstrated the lack of consensus and clarity in the classification system of lumbar arachnoiditis. The presence of synechia has high interreader agreement only among most experienced readers and promises to be a useful tool in assessing arachnoiditis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Evidence Level<\/jats:title><jats:p>3<\/jats:p><\/jats:sec><jats:sec><jats:title>Technical Efficacy<\/jats:title><jats:p>Stage 2<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.27583","type":"journal-article","created":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T07:19:36Z","timestamp":1614583176000},"page":"904-909","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["<scp>MRI<\/scp> Findings of Arachnoiditis, Revisited. Is Classification Possible?"],"prefix":"10.1002","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8483-3653","authenticated-orcid":false,"given":"Maria","family":"El Homsi","sequence":"first","affiliation":[{"name":"Department of Radiology Memorial Sloan Kettering Cancer Center  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karem","family":"Gharzeddine","sequence":"additional","affiliation":[{"name":"Department of Radiology Memorial Sloan Kettering Cancer Center  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan","family":"Cuevas","sequence":"additional","affiliation":[{"name":"BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6283-0558","authenticated-orcid":false,"given":"Julio","family":"Arevalo\u2010Perez","sequence":"additional","affiliation":[{"name":"Department of Radiology Memorial Sloan Kettering Cancer Center  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karim","family":"Rebeiz","sequence":"additional","affiliation":[{"name":"Department of Radiology Memorial Sloan Kettering Cancer Center  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nabil J.","family":"Khoury","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology American University of Beirut Medical Center  Beirut Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hicham","family":"Moukaddam","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology American University of Beirut Medical Center  Beirut Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,2,28]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006416-200305000-00010"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-197803000-00006"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.149.5.1025"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/014107689008300418"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199004000-00011"},{"issue":"4","key":"e_1_2_6_7_1","first-page":"296","article-title":"Chronic adhesive spinal arachnoiditis: Pathogenesis, prognosis, and treatment","volume":"2","author":"Long DM","year":"1992","journal-title":"Neurosurg 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