{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T04:24:31Z","timestamp":1771302271262,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,3,11]],"date-time":"2022-03-11T00:00:00Z","timestamp":1646956800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Due to the long acquisition time and high cost of multiparametric magnetic resonance imaging (mpMRI), biparametric and, more recently, fast prostate magnetic resonance imaging (fpMRI) protocols have been described. However, there is insufficient data about the diagnostic performance and cost of fpMRI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To compare the diagnostic performances and cost analysis of fpMRI and mpMRI in clinically significant prostate cancer (csPCA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Type<\/jats:title><jats:p>Retrospective.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>A total of 103 patients (63 had csPCA) with a mean age of 66.83 (\u00b1\u20097.22) years were included.<\/jats:p><\/jats:sec><jats:sec><jats:title>Field Strength\/Sequence<\/jats:title><jats:p>A 1.5\u2010T; T1\u2010 and T2\u2010weighted turbo spin\u2010echo imaging (T1WI and T2WI), echo\u2010planar diffusion\u2010weighted images, and dynamic contrast\u2010enhanced T1W imaging.<\/jats:p><\/jats:sec><jats:sec><jats:title>Assessment<\/jats:title><jats:p>Three readers independently evaluated the fpMRI and mpMRI images in different sessions blinded to all patient information. Diagnostic performances of fpMRI and mpMRI were evaluated. Kappa coefficient (<jats:italic>\u03ba<\/jats:italic>) was used to determine the interreader and intrareader agreement. A detailed cost analysis was performed for each protocol.<\/jats:p><\/jats:sec><jats:sec><jats:title>Statistical Tests<\/jats:title><jats:p>Receiver operating characteristics analysis, area under the curve (AUC), and <jats:italic>\u03ba<\/jats:italic> test were used. Diagnostic performance parameters were also calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 63 malignant index lesions (csPCA), 53\/63 of those (84.1%) originated from the peripheral zone and 10\/63 lesions (15.9%) originated from the transition zone. The AUC values for fpMRI were 0.878 for reader 1, 0.937 for reader 2, and 0.855 for reader 3. For mpMRI, the AUC values were 0.893 for reader 1, 0.94 for reader 2, and 0.862 for reader 3. Inter and intrareader agreements were moderate to substantial (<jats:italic>\u03ba<\/jats:italic> range, 0.5\u20130.79). The total cost per examination was calculated as \u20ac12.39 and \u20ac30.10 for fpMRI and mpMRI, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Data Conclusions<\/jats:title><jats:p>Fast MRI protocol has similar diagnostic performance with mpMRI in detecting csPCA, and fpMRI can be considered an alternative protocol that could create a lower financial burden on health\u2010care systems.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4<\/jats:p><\/jats:sec><jats:sec><jats:title>Technical Efficacy Stage<\/jats:title><jats:p>6<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.28142","type":"journal-article","created":{"date-parts":[[2022,3,11]],"date-time":"2022-03-11T13:14:33Z","timestamp":1647004473000},"page":"1437-1447","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Comparison of Multiparametric and Fast <scp>MRI<\/scp> Protocols in Detecting Clinically Significant Prostate Cancer and a Detailed Cost Analysis"],"prefix":"10.1002","volume":"56","author":[{"given":"Kadir Han","family":"Alver","sequence":"first","affiliation":[{"name":"Department of Radiology, School of Medicine University of Pamukkale  Denizli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet Baki","family":"Yagci","sequence":"additional","affiliation":[{"name":"Department of Radiology, School of Medicine University of Pamukkale  Denizli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayse Ruksan","family":"Utebey","sequence":"additional","affiliation":[{"name":"Department of Radiology, School of Medicine University of Pamukkale  Denizli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nilay Sen","family":"Turk","sequence":"additional","affiliation":[{"name":"Department of Pathology, School of Medicine University of Pamukkale  Denizli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8614-5387","authenticated-orcid":false,"given":"Furkan","family":"Ufuk","sequence":"additional","affiliation":[{"name":"Department of Radiology, School of Medicine University of Pamukkale  Denizli 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