{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:22:50Z","timestamp":1747149770109,"version":"3.40.5"},"reference-count":33,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,3,28]],"date-time":"2022-03-28T00:00:00Z","timestamp":1648425600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100006318","name":"Universidad Carlos III de Madrid","doi-asserted-by":"publisher","award":["PI17\/01836"],"award-info":[{"award-number":["PI17\/01836"]}],"id":[{"id":"10.13039\/501100006318","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009664","name":"Sociedad Espa\u00f1ola de Cardiolog\u00eda","doi-asserted-by":"publisher","award":["SEC\/FECINV\u2010CLI 21\/024"],"award-info":[{"award-number":["SEC\/FECINV\u2010CLI 21\/024"]}],"id":[{"id":"10.13039\/100009664","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Stress cardiac MRI permits comprehensive evaluation of patients with known or suspected chronic coronary syndromes (CCS). The impact of sex on the use of invasive cardiac angiography (ICA) after vasodilator stress cardiac MRI is unclear.<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To evaluate the impact of sex on ICA use after vasodilator stress cardiac MRI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study type<\/jats:title><jats:p>Retrospective.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>A total of 6229 consecutive patients (age [mean\u2009\u00b1\u2009standard deviation] 65.2\u2009\u00b1\u200911.5\u2009years, 38.1% women).<\/jats:p><\/jats:sec><jats:sec><jats:title>Field Strength\/Sequence<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">A 5\u2010T<\/jats:styled-content>; a steady\u2010state free\u2010precession cine sequence; stress first\u2010pass perfusion imaging; late enhancement imaging.<\/jats:p><\/jats:sec><jats:sec><jats:title>Assessment<\/jats:title><jats:p>Patients underwent vasodilator stress cardiac MRI for known or suspected CCS. The ischemic burden (at stress first\u2010pass perfusion imaging) was computed (17\u2010segment model).<\/jats:p><\/jats:sec><jats:sec><jats:title>Statistical Tests<\/jats:title><jats:p>Multivariate logistic regression was used to evaluate the potential differential association between ischemic burden and use of cardiac MRI\u2010related ICA across sex.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 1109 (17.8%) patients were referred to ICA, among which there were significantly more men (762, 19.7%) than women (347, 14.6%). Overall, after multivariate adjustment, female sex was not associated with lower use of ICA (odds ratio [OR]\u00a0=\u00a00.99; confidence interval [CI] 95%: 0.84\u20131.18, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.934). However, significant sex differences were detected across ischemic burden. Whereas women with nonischemic vasodilator stress cardiac MRI (0 ischemic segments) were less commonly submitted to ICA (OR\u00a0=\u00a00.49; CI 95%: 0.35\u20130.69) in patients with ischemia (&gt;1 ischemic segment), adjusted use of ICA was more frequent in women than men (OR\u00a0=\u00a01.27; CI 95%: 1.1\u20131.5).<\/jats:p><\/jats:sec><jats:sec><jats:title>Data Conclusions<\/jats:title><jats:p>In patients with known or suspected CCS submitted to undergo vasodilator stress cardiac MRI, cardiac MRI\u2010related ICA may be overused in men without ischemia. Furthermore, ICA referral in patients with negative ischemia resulted in greater odds of revascularization in men.<\/jats:p><\/jats:sec><jats:sec><jats:title>Evidence Level<\/jats:title><jats:p>3<\/jats:p><\/jats:sec><jats:sec><jats:title>Technical Efficacy<\/jats:title><jats:p>Stage 5<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.28163","type":"journal-article","created":{"date-parts":[[2022,3,28]],"date-time":"2022-03-28T14:14:07Z","timestamp":1648476847000},"page":"1680-1690","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Sex Effect in the Decision to Perform Invasive Coronary Angiography in Patients With Chronic Coronary Syndrome After Undergoing Vasodilator Stress <scp>MRI<\/scp>"],"prefix":"10.1002","volume":"56","author":[{"given":"Patricia","family":"Palau","sequence":"first","affiliation":[{"name":"Department of Cardiology Hospital Cl\u00ednico Universitario de Valencia  Valencia Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria del Hospital Cl\u00ednico Universitario de Valencia (INCLIVA)  Valencia Spain"},{"name":"Faculty of Medicine Universitat de Val\u00e8ncia  Valencia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julio","family":"N\u00fa\u00f1ez","sequence":"additional","affiliation":[{"name":"Department of Cardiology Hospital Cl\u00ednico Universitario de Valencia  Valencia Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria del Hospital Cl\u00ednico Universitario de Valencia (INCLIVA)  Valencia Spain"},{"name":"Faculty of Medicine Universitat de Val\u00e8ncia  Valencia Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Cardiovasculares (CIBER\u2010CV)  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose V.","family":"Monmeneu","sequence":"additional","affiliation":[{"name":"Cardiovascular Unit, ASCIRES Biomedical Group  Valencia 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