{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T07:05:19Z","timestamp":1790751919341,"version":"4.1.0"},"reference-count":40,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T00:00:00Z","timestamp":1655251200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The relationship of left atrial (LA) strain to high\u2010risk heart failure (HF) events in patients with left ventricular myocardial noncompaction (LVNC) remains to be thoroughly investigated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To evaluate the LA performance in patients with LVNC, and to investigate the prognostic value of LA phasic strain on high\u2010risk HF events, and its influencing factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Type<\/jats:title><jats:p>Retrospective.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>A total of 95 LVNC patients (74 with <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> enlargement [<jats:styled-content style=\"fixed-case\">LAE<\/jats:styled-content>] and 21 without <jats:styled-content style=\"fixed-case\">LAE<\/jats:styled-content>) and 50 healthy controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Field Strength\/sequence<\/jats:title><jats:p>A 3.0\u2009T, balanced steady\u2010state free\u2010precession cine imaging.<\/jats:p><\/jats:sec><jats:sec><jats:title>Assessment<\/jats:title><jats:p>LA longitudinal strains were measured by cardiac MRI feature tracking technique. LA volume index (LAVI) and LA ejection fraction (LAEF) were calculated. Their intraobserver and interobserver reproducibility were evaluated. The primary outcome was high\u2010risk HF events, a composite of first HF hospitalization, hospitalization for worsening HF and death from HF.<\/jats:p><\/jats:sec><jats:sec><jats:title>Statistical Tests<\/jats:title><jats:p>Student's t\/Mann\u2013Whitney U, one\u2010way analysis of variance\/Kruskal\u2013Wallis, Chi\u2010squared, receiver operating characteristic, Kaplan\u2013Meier, log\u2010rank, Cox regression, Pearson and Spearman correlation and linear regression analyses were performed. The significance threshold was set at <jats:italic>P<\/jats:italic>\u2009&lt;\u20090 .05.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>LAEF and LA longitudinal strains decreased in LVNC patients irrespective of the presence of LAE. During a median follow\u2010up of 32.17\u00a0months, high\u2010risk HF occurred in 13 (13.68%) patients. Patients with increased LAVI, decreased LAEF and decreased LA longitudinal strain had significantly higher risks of high\u2010risk HF events. In patients with LVNC, LA reservoir strain (\u03b5s) was independently associated with high\u2010risk HF (hazard ratio\u00a0=\u00a023.208 [95% CI: 2.993\u2013179.967]). LV global longitudinal strain (LV GLS) (\u03b2\u00a0=\u00a0\u22121.783 [95% CI: \u22122.493 to \u22121.073]) was significantly and independently associated with \u03b5s. Intraobserver and interobserver reproducibility was excellent for LAVI, LAEF, and LA strain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In patients with LVNC, \u03b5s was an independent predictor for high\u2010risk HF events. LV GLS was an independent determinant of \u03b5s in LVNC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Evidence Level<\/jats:title><jats:p>4<\/jats:p><\/jats:sec><jats:sec><jats:title>Technical Efficacy<\/jats:title><jats:p>Stage 4<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.28292","type":"journal-article","created":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T11:33:22Z","timestamp":1655292802000},"page":"559-575","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Prognostic Value of Left Atrial Reservoir Strain in Left Ventricular Myocardial Noncompaction: A 3.0\u2009T Cardiac Magnetic Resonance Feature Tracking Study"],"prefix":"10.1002","volume":"57","author":[{"given":"Pei\u2010Lun","family":"Han","sequence":"first","affiliation":[{"name":"Department of Radiology West China Hospital, Sichuan University  Chengdu China"},{"name":"West China Biomedical Big Data Center West China Hospital, Sichuan University  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