{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T16:45:51Z","timestamp":1782319551187,"version":"3.54.5"},"reference-count":40,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,9,12]],"date-time":"2022-09-12T00:00:00Z","timestamp":1662940800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100011913","name":"Kaohsiung Veterans General Hospital","doi-asserted-by":"publisher","award":["KSVGH110\u2010091"],"award-info":[{"award-number":["KSVGH110\u2010091"]}],"id":[{"id":"10.13039\/501100011913","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011913","name":"Kaohsiung Veterans General Hospital","doi-asserted-by":"publisher","award":["KSVGH111\u2010101"],"award-info":[{"award-number":["KSVGH111\u2010101"]}],"id":[{"id":"10.13039\/501100011913","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MOST106\u20102314\u2010B\u2010007\u2010003\u2010MY3"],"award-info":[{"award-number":["MOST106\u20102314\u2010B\u2010007\u2010003\u2010MY3"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MOST109\u20102314\u2010B\u2010007\u2010003\u2010MY3"],"award-info":[{"award-number":["MOST109\u20102314\u2010B\u2010007\u2010003\u2010MY3"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2023,5]]},"abstract":"Background<\/jats:title>The myocardial kinetic energy (KE<\/jats:styled-content>) and its association with pulmonary regurgitation (PR<\/jats:styled-content>) have yet to be investigated in repaired tetralogy of Fallot (rTOF<\/jats:styled-content>) patients.<\/jats:p><\/jats:sec>Purpose<\/jats:title>To evaluate the adaptation of myocardial KE in rTOF patients by tissue phase mapping (TPM).<\/jats:p><\/jats:sec>Study Type<\/jats:title>Prospective.<\/jats:p><\/jats:sec>Population<\/jats:title>A total of 49 rTOF patients (23\u2009\u00b1\u20095\u2009years old; male\u00a0=\u00a032), 47 normal controls (22\u2009\u00b1\u20091\u2009year old; male\u00a0=\u00a029).<\/jats:p><\/jats:sec>Field Strength\/Sequence<\/jats:title>3\u2010T\/2D dark\u2010blood three\u2010directional velocity\u2010encoded gradient\u2010echo sequence.<\/jats:p><\/jats:sec>Assessment<\/jats:title>Left and right ventricle (LV<\/jats:styled-content>, RV<\/jats:styled-content>) myocardial KE<\/jats:styled-content> in radial (KEr<\/jats:sub><\/jats:styled-content>), circumferential (KE\u00f8<\/jats:sub><\/jats:styled-content>), longitudinal (KEz<\/jats:sub><\/jats:styled-content>) directions. The proportions of KE<\/jats:styled-content> in each direction to the sum of all KE<\/jats:styled-content> (KEr\u00f8z<\/jats:sub><\/jats:styled-content>): %KEr<\/jats:sub><\/jats:styled-content>, %KE\u00f8<\/jats:sub><\/jats:styled-content>, %KEz<\/jats:sub><\/jats:styled-content>. PR<\/jats:styled-content> fraction.<\/jats:p><\/jats:sec>Statistical Test<\/jats:title>Student's t<\/jats:italic> test, multivariable regression. Statistical significance: P<\/jats:italic>\u00a0<\u20090.05.<\/jats:p><\/jats:sec>Results<\/jats:title>In rTOF group, LV KEz<\/jats:sub> remained normal in systole (P<\/jats:italic>\u00a0=\u00a00.565) and diastole (P<\/jats:italic>\u00a0=\u00a00.210), whereas diastolic LV %KEz<\/jats:sub> (62%\u2009\u00b1\u200914% vs. 72%\u2009\u00b1\u20097%) and systolic LV %KE\u00f8<\/jats:sub> (9%\u2009\u00b1\u20096% vs. 20%\u2009\u00b1\u20097%) were significantly decreased. The KEr<\/jats:sub> and %KEr<\/jats:sub> of both ventricles significantly increased in the rTOF group (RV in diastole: 6\u2009\u00b1\u20093 vs. 3\u2009\u00b1\u20091\u2009\u03bcJ and 54%\u2009\u00b1\u200913% vs. 27%\u2009\u00b1\u20097%). The rTOF group exhibited significantly higher RV\/LV ratios of %KEr<\/jats:sub> (systole: 1.3\u2009\u00b1\u20090.3 vs. 1.0\u2009\u00b1\u20090.3) and %KE\u00f8<\/jats:sub> (systole: 1.6\u2009\u00b1\u20090.8 vs. 1.0\u2009\u00b1\u20090.3) and significantly lower ratios of %KEz<\/jats:sub> in systole (0.7\u2009\u00b1\u20090.2 vs. 1.0\u2009\u00b1\u20090.1) and diastole (0.5\u2009\u00b1\u20090.2 vs. 0.9\u2009\u00b1\u20090.1). In multivariable regression analysis, the RV peak systolic KEr\u00f8z<\/jats:sub>, RV systolic KEz<\/jats:sub>, and LV diastolic %KE\u00f8<\/jats:sub> were independently associated with PR fraction in the rTOF group (adjusted R<\/jats:italic>2<\/jats:sup>\u00a0=\u00a00.479).<\/jats:p><\/jats:sec>Data Conclusion<\/jats:title>In rTOF patients, the adaptation of the KE proportion occurred earlier than that of the KE amplitude, and the biventricular balance of %KE was disrupted. PR may cause differential KE adaptation in RV and LV. TPM\u2010derived KE may be useful in investigation of myocardial adaptation in rTOF patients.<\/jats:p><\/jats:sec>Evidence Level<\/jats:title>2<\/jats:p><\/jats:sec>Technical Efficacy<\/jats:title>Stage 3<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.28420","type":"journal-article","created":{"date-parts":[[2022,9,12]],"date-time":"2022-09-12T12:14:31Z","timestamp":1662984871000},"page":"1492-1504","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Differential Adaptation of Biventricular Myocardial Kinetic Energy in Patients With Repaired Tetralogy of Fallot Assessed by MR<\/scp> Tissue Phase Mapping"],"prefix":"10.1002","volume":"57","author":[{"given":"Shi\u2010Ying","family":"Ke","sequence":"first","affiliation":[{"name":"Department of Biomedical Engineering and Environmental Sciences National Tsing Hua University Hsinchu Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken\u2010Pen","family":"Weng","sequence":"additional","affiliation":[{"name":"School of Medicine National Yang Ming Chiao Tung University Taipei Taiwan"},{"name":"Congenital Structural Heart Disease Center, Department of Pediatrics Kaohsiung Veterans General Hospital Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng\u2010Chu","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering and Environmental Sciences National Tsing Hua University Hsinchu Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming\u2010Ting","family":"Wu","sequence":"additional","affiliation":[{"name":"School of Medicine National Yang Ming Chiao Tung University Taipei Taiwan"},{"name":"Department of Radiology Kaohsiung Veterans General Hospital Kaohsiung Taiwan"},{"name":"Institute of Clinical Medicine National Yang Ming Chiao Tung University Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi\u2010He","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Radiology Kaohsiung Veterans General Hospital Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuang\u2010Jen","family":"Chien","sequence":"additional","affiliation":[{"name":"Congenital Structural Heart Disease Center, Department of Pediatrics Kaohsiung Veterans General Hospital Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chu\u2010Chuan","family":"Lin","sequence":"additional","affiliation":[{"name":"Congenital Structural Heart Disease Center, Department of Pediatrics Kaohsiung Veterans General Hospital Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai\u2010Sheng","family":"Hsieh","sequence":"additional","affiliation":[{"name":"Department of Pediatrics China Medical University Children's Hospital Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming\u2010Hua","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Radiology Kaohsiung Veterans General Hospital Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun\u2010Yen","family":"Pan","sequence":"additional","affiliation":[{"name":"Congenital Structural Heart Disease Center, Department of Pediatrics Kaohsiung Veterans General Hospital Kaohsiung Taiwan"},{"name":"Department of Cardiovascular Surgery Kaohsiung Veterans General Hospital Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6318-1377","authenticated-orcid":false,"given":"Hsu\u2010Hsia","family":"Peng","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering and Environmental Sciences National Tsing Hua University Hsinchu Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,9,12]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2013.11.009"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.116.004270"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02714-8"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2020.02.021"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2015.10.006"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2021.07.026"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12968-017-0410-2"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.25830"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2014.11.085"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-018-5385-3"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.108.813857"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2006.02.066"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-019-04549-4"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-016-0894-0"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2383041992"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0237193"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-017-4908-7"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-019-01544-6"},{"key":"e_1_2_7_20_1","unstructured":"PescatelloLS ArenaR RiebeD ThompsonP KluwerW. American College of Sports Medicine. ACSM's Guidelines for exercise testing and prescription. Philadelphia PA USA:Lippincott Williams & Wilkins;2014."},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.21561"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00478.2003"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10741-021-10105-w"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12968-015-0111-7"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12968-018-0460-0"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-018-5538-4"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1186\/1532-429X-14-43"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2017.01.025"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.76.3.280"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2010.02.015"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.115.003029"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.08.030"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-020-07643-6"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12947-021-00260-3"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2017.11.017"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00575.2003"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.27034"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1136\/heart.84.4.416"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-010-0252-5"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jew273"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12968-016-0268-8"}],"container-title":["Journal of Magnetic Resonance Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmri.28420","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jmri.28420","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmri.28420","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T18:28:41Z","timestamp":1692728921000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmri.28420"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,12]]},"references-count":40,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["10.1002\/jmri.28420"],"URL":"https:\/\/doi.org\/10.1002\/jmri.28420","archive":["Portico"],"relation":{},"ISSN":["1053-1807","1522-2586"],"issn-type":[{"value":"1053-1807","type":"print"},{"value":"1522-2586","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,12]]},"assertion":[{"value":"2022-05-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}