{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T21:21:23Z","timestamp":1773696083163,"version":"3.50.1"},"reference-count":40,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,12,16]],"date-time":"2022-12-16T00:00:00Z","timestamp":1671148800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82271961"],"award-info":[{"award-number":["82271961"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81621003"],"award-info":[{"award-number":["81621003"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81974278"],"award-info":[{"award-number":["81974278"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFC2009900"],"award-info":[{"award-number":["2022YFC2009900"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2023,9]]},"abstract":"Background<\/jats:title>The human brain has ability to reorganize itself in response to glioma. However, the mechanism of cortical reorganization remains unclear.<\/jats:p><\/jats:sec>Purpose<\/jats:title>To investigate alterations in cortical thickness and local gyration index (LGI) in patients with unilateral frontal lobe diffuse low\u2010grade glioma (DLGG).<\/jats:p><\/jats:sec>Study Type<\/jats:title>Retrospective.<\/jats:p><\/jats:sec>Subjects<\/jats:title>Ninety\u2010nine patients with histopathologically proven DLGG invading the left frontal lobe (LF; N\u00a0=\u00a056) or the right frontal lobe (RF; N\u00a0=\u00a043), and healthy controls (HC; N\u00a0=\u00a053).<\/jats:p><\/jats:sec>Field Strength\/Sequence<\/jats:title>3.0\u2009T, 3D T1<\/jats:styled-content>\u2010weighted images and gadolinium enhanced T1<\/jats:styled-content>\u2010weighted images using magnetization\u2010prepared rapid gradient echo sequence, T2<\/jats:styled-content>\u2010weighted images, and fluid\u2010attenuated inversion recovery<\/jats:styled-content> using turbo spin echo sequence.<\/jats:p><\/jats:sec>Assessment<\/jats:title>In patients with DLGG, virtual brain grafting combined with Freesurfer was utilized to enable automated cortical thickness and LGI calculation. In HC, standard FreeSurfer pipeline was applied to calculate these measures. Radiomic features were extracted from glioma using Pyradiomic software.<\/jats:p><\/jats:sec>Statistical Tests<\/jats:title>General linear model and Pearson's correlation analysis. A P<\/jats:italic> value <0.05 was considered statistically significant.<\/jats:p><\/jats:sec>Results<\/jats:title>For LF patients, there was significantly increased cortical thickness in the rostral middle frontal gyrus, significantly reduced cortical thickness in the precentral gyrus and hypogyrification in the lingual and medial orbitofrontal (MOF) gyrus in contralateral hemisphere. For RF patients, there was significantly increased cortical thickness in the middle temporal, lateral occipital extending to isthmus cingulate gyrus, significantly reduced cortical thickness in the precentral gyrus and hypogyrification in the lingual gyrus in the contralateral hemisphere. A negative association between four textural features of DLGG and LGI in the right MOF gyrus of LF group was found (r<\/jats:italic>\u00a0=\u00a0\u22120.609, \u22120.442, \u22120.545, and \u22120.417, respectively).<\/jats:p><\/jats:sec>Data Conclusion<\/jats:title>Cortical thickness compensation was shown in contralateral homotopic location and some distant contralateral regions. Additionally, there was decreased cortical thickness in the contralateral precentral gyrus and hypogyrification in contralateral lingual gyrus.<\/jats:p><\/jats:sec>Evidence Level<\/jats:title>4<\/jats:p><\/jats:sec>Technical Efficacy<\/jats:title>Stage 2<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.28562","type":"journal-article","created":{"date-parts":[[2022,12,16]],"date-time":"2022-12-16T09:25:53Z","timestamp":1671182753000},"page":"741-749","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["An MRI<\/scp> Study Combining Virtual Brain Grafting and Surface\u2010Based Morphometry Analysis to Investigate Contralateral Alterations in Cortical Morphology in Patients With Diffuse Low\u2010Grade Glioma"],"prefix":"10.1002","volume":"58","author":[{"given":"Simin","family":"Zhang","sequence":"first","affiliation":[{"name":"Huaxi MR Research Center (HMRRC), Department of Radiology West China Hospital of Sichuan University Chengdu China"},{"name":"Huaxi Glioma Center West China Hospital of Sichuan University Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huaiqiang","family":"Sun","sequence":"additional","affiliation":[{"name":"Huaxi MR Research Center (HMRRC), Department of Radiology West China Hospital of Sichuan University Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xibiao","family":"Yang","sequence":"additional","affiliation":[{"name":"Huaxi Glioma Center West China Hospital of Sichuan University Chengdu China"},{"name":"Department of Radiology West China Hospital of Sichuan University Chengdu Sichuan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinyue","family":"Wan","sequence":"additional","affiliation":[{"name":"Huaxi MR Research Center (HMRRC), Department of Radiology West China Hospital of Sichuan University Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0870-200X","authenticated-orcid":false,"given":"QiaoYue","family":"Tan","sequence":"additional","affiliation":[{"name":"Division of Radiation Physics, State Key Laboratory of Biotherapy and Cancer Center West China Hospital of Sichuan University Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuang","family":"Li","sequence":"additional","affiliation":[{"name":"Huaxi MR Research Center (HMRRC), Department of Radiology West China Hospital of Sichuan University Chengdu China"},{"name":"Huaxi Glioma Center West China Hospital of Sichuan University Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanbin","family":"Shao","sequence":"additional","affiliation":[{"name":"Huaxi MR Research Center (HMRRC), Department of Radiology West China Hospital of Sichuan University Chengdu China"},{"name":"Huaxi Glioma Center West China Hospital of Sichuan University Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaorui","family":"Su","sequence":"additional","affiliation":[{"name":"Huaxi MR Research Center (HMRRC), Department of Radiology West China Hospital of Sichuan University Chengdu China"},{"name":"Research Unit of Psychoradiology Chinese Academy of Medical Sciences Chengdu china"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8480-8987","authenticated-orcid":false,"given":"Qiang","family":"Yue","sequence":"additional","affiliation":[{"name":"Huaxi Glioma Center West China Hospital of Sichuan University Chengdu China"},{"name":"Department of Radiology West China Hospital of Sichuan University Chengdu Sichuan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5912-4871","authenticated-orcid":false,"given":"Qiyong","family":"Gong","sequence":"additional","affiliation":[{"name":"Department of Radiology West China Xiamen Hospital of Sichuan University Xiamen Fujian China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,12,16]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awu013"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awf148"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2019.6413"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diii.2014.08.001"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(05)70140-X"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000006517"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.00794"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2020.00010"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dib.2015.10.044"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11910-001-0060-4"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2021.117731"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2011.2138152"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0159540"},{"key":"e_1_2_8_15_1","doi-asserted-by":"crossref","unstructured":"ZhangF KahaliP SuterY et al.Automated connectivity\u2010based groupwise cortical atlas generation: Application to data of neurosurgical patients with brain tumors for cortical parcellation prediction. 2017 IEEE 14th International Symposium on Biomedical Imaging2017:774\u2013777.","DOI":"10.1109\/ISBI.2017.7950633"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0908073106"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/neuonc\/noab106"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncom.2020.00010"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.24750"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-75238-9_25"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2012.01.021"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2006.01.021"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2007.903576"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2021.636573"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2019.04.248"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1714801114"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhj138"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/scan\/nsw080"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2017.09.031"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.24616"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/nop\/npv017"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(01)00423-8"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2007.10.040"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2020.102406"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.30.051606.094334"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11060-012-0934-0"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/385313a0"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2019.00536"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.5114\/fn.2014.45563"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00432-020-03153-6"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2018180200"}],"container-title":["Journal of Magnetic Resonance Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmri.28562","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jmri.28562","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmri.28562","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T06:57:17Z","timestamp":1692341837000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmri.28562"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,16]]},"references-count":40,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["10.1002\/jmri.28562"],"URL":"https:\/\/doi.org\/10.1002\/jmri.28562","archive":["Portico"],"relation":{},"ISSN":["1053-1807","1522-2586"],"issn-type":[{"value":"1053-1807","type":"print"},{"value":"1522-2586","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,16]]},"assertion":[{"value":"2022-09-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}