{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T17:48:28Z","timestamp":1778089708207,"version":"3.51.4"},"reference-count":39,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T00:00:00Z","timestamp":1675900800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000274","name":"British Heart Foundation","doi-asserted-by":"publisher","award":["RG\/20\/1\/34802"],"award-info":[{"award-number":["RG\/20\/1\/34802"]}],"id":[{"id":"10.13039\/501100000274","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000274","name":"British Heart Foundation","doi-asserted-by":"publisher","award":["PG\/18\/59\/33955"],"award-info":[{"award-number":["PG\/18\/59\/33955"]}],"id":[{"id":"10.13039\/501100000274","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000266","name":"Engineering and Physical Sciences Research Council","doi-asserted-by":"publisher","award":["EP\/P007619"],"award-info":[{"award-number":["EP\/P007619"]}],"id":[{"id":"10.13039\/501100000266","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000266","name":"Engineering and Physical Sciences Research Council","doi-asserted-by":"publisher","award":["EP\/P032311\/1"],"award-info":[{"award-number":["EP\/P032311\/1"]}],"id":[{"id":"10.13039\/501100000266","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000266","name":"Engineering and Physical Sciences Research Council","doi-asserted-by":"publisher","award":["EP\/P001009\/1"],"award-info":[{"award-number":["EP\/P001009\/1"]}],"id":[{"id":"10.13039\/501100000266","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000266","name":"Engineering and Physical Sciences Research Council","doi-asserted-by":"publisher","award":["EP\/V044087\/1"],"award-info":[{"award-number":["EP\/V044087\/1"]}],"id":[{"id":"10.13039\/501100000266","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100023312","name":"Centre For Medical Engineering, King\u2019s College London","doi-asserted-by":"publisher","award":["NS\/A000049\/1"],"award-info":[{"award-number":["NS\/A000049\/1"]}],"id":[{"id":"10.13039\/501100023312","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002850","name":"Fondo Nacional de Desarrollo Cient\u00edfico y Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["1210638"],"award-info":[{"award-number":["1210638"]}],"id":[{"id":"10.13039\/501100002850","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002850","name":"Fondo Nacional de Desarrollo Cient\u00edfico y Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["1210637"],"award-info":[{"award-number":["1210637"]}],"id":[{"id":"10.13039\/501100002850","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2023,10]]},"abstract":"\n Background<\/jats:title>\n Bright\u2010blood lumen and black\u2010blood vessel wall imaging are required for the comprehensive assessment of aortic disease. These images are usually acquired separately, resulting in long examinations and potential misregistration between images.<\/jats:p>\n <\/jats:sec>\n \n Purpose<\/jats:title>\n To characterize the performance of an accelerated and respiratory motion\u2010compensated three\u2010dimensional (3D) cardiac MRI technique for simultaneous contrast\u2010free aortic lumen and vessel wall imaging with an interleaved T2 and inversion recovery prepared sequence (iT2Prep\u2010BOOST).<\/jats:p>\n <\/jats:sec>\n \n Study Type<\/jats:title>\n Prospective.<\/jats:p>\n <\/jats:sec>\n \n Population<\/jats:title>\n A total of 30 consecutive patients with aortopathy referred for a clinically indicated cardiac MRI examination (9 females, mean age\u2009\u00b1\u2009standard deviation: 32\u2009\u00b1\u200912\u2009years).<\/jats:p>\n <\/jats:sec>\n \n Field Strength\/Sequence<\/jats:title>\n \n 1.5\u2010T<\/jats:styled-content>\n ; bright\u2010blood\n MR<\/jats:styled-content>\n angiography (diaphragmatic navigator\u2010gated\n T2<\/jats:styled-content>\n \u2010prepared\n 3D<\/jats:styled-content>\n balanced steady\u2010state free precession [\n bSSFP<\/jats:styled-content>\n ],\n T2Prep\u2010bSSFP<\/jats:styled-content>\n ), breath\u2010held black\u2010blood two\u2010dimensional (\n 2D<\/jats:styled-content>\n ) half acquisition single\u2010shot turbo spin echo (\n HASTE<\/jats:styled-content>\n ), and\n 3D bSSFP iT2Prep\u2010BOOST<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Assessment<\/jats:title>\n iT2Prep\u2010BOOST bright\u2010blood images were compared to T2prep\u2010bSSFP images in terms of aortic vessel dimensions, lumen\u2010to\u2010myocardium contrast ratio (CR), and image quality (diagnostic confidence, vessel sharpness and presence of artifacts, assessed by three cardiologists on a 4\u2010point scale, 1: nondiagnostic to 4: excellent). The iT2Prep\u2010BOOST black\u2010blood images were compared to 2D HASTE images for quantification of wall thickness. A visual comparison between computed tomography (CT) and iT2Prep\u2010BOOST was performed in a patient with chronic aortic dissection.<\/jats:p>\n <\/jats:sec>\n \n Statistical Tests<\/jats:title>\n \n Paired\n t<\/jats:italic>\n \u2010tests, Wilcoxon signed\u2010rank tests, intraclass correlation coefficient (ICC), Bland\u2013Altman analysis. A\n P<\/jats:italic>\n value\u2009<\u20090.05 was considered statistically significant.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Bright\u2010blood iT2Prep\u2010BOOST resulted in significantly improved image quality (mean\u2009\u00b1\u2009standard deviation 3.8\u2009\u00b1\u20090.5 vs. 3.3\u2009\u00b1\u20090.8) and CR (2.9\u2009\u00b1\u20090.8 vs. 1.8\u2009\u00b1\u20090.5) compared with T2Prep\u2010bSSFP, with a shorter scan time (7.8\u2009\u00b1\u20091.7\u00a0minutes vs. 12.9\u2009\u00b1\u20093.4\u00a0minutes) while providing a complementary 3D black\u2010blood image. Aortic lumen diameter and vessel wall thickness measurements in bright\u2010blood and black\u2010blood images were in good agreement with T2Prep\u2010bSSFP and HASTE images (<0.02\u2009cm and <0.005\u2009cm bias, respectively) and good intrareader (ICC\u2009>\u20090.96) and interreader (ICC\u2009>\u20090.94) agreement was observed for all measurements.<\/jats:p>\n <\/jats:sec>\n \n Data Conclusion<\/jats:title>\n iT2Prep\u2010BOOST might enable time\u2010efficient simultaneous bright\u2010 and black\u2010blood aortic imaging, with improved image quality compared to T2Prep\u2010bSSFP and HASTE imaging, and comparable measurements for aortic wall and lumen dimensions.<\/jats:p>\n <\/jats:sec>\n \n Evidence Level<\/jats:title>\n 2.<\/jats:p>\n <\/jats:sec>\n \n Technical Efficacy<\/jats:title>\n Stage 2.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/jmri.28613","type":"journal-article","created":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T09:30:40Z","timestamp":1675935040000},"page":"1110-1122","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Simultaneous Highly Efficient Contrast\u2010Free Lumen and Vessel Wall\n MR<\/scp>\n Imaging for Anatomical Assessment of Aortic Disease"],"prefix":"10.1002","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5278-4546","authenticated-orcid":false,"given":"Camila","family":"Munoz","sequence":"first","affiliation":[{"name":"School of Biomedical Engineering and Imaging Sciences King's College London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0353-5778","authenticated-orcid":false,"given":"Anastasia","family":"Fotaki","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering and Imaging Sciences King's College London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alina","family":"Hua","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering and Imaging Sciences King's College London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reza","family":"Hajhosseiny","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering and Imaging Sciences King's College London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karl P.","family":"Kunze","sequence":"additional","affiliation":[{"name":"MR Research Collaborations Siemens Healthcare Limited Frimley UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tevfik F.","family":"Ismail","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering and Imaging Sciences King's College London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Radhouene","family":"Neji","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering and Imaging Sciences King's College London London UK"},{"name":"MR Research Collaborations Siemens Healthcare Limited Frimley UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kuberan","family":"Pushparajah","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering and Imaging Sciences King's College London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ren\u00e9 M.","family":"Botnar","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering and Imaging Sciences King's College London London UK"},{"name":"Escuela de Ingenier\u00eda, Pontificia Universidad Cat\u00f3lica de Chile Santiago Chile"},{"name":"Instituto de Ingenier\u00eda Biol\u00f3gica y M\u00e9dica, Pontificia Universidad Cat\u00f3lica de Chile Santiago Chile"},{"name":"Millenium Institute for Intelligent Healthcare Engineering iHEALTH Santiago Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Prieto","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering and Imaging Sciences King's College London London UK"},{"name":"Escuela de Ingenier\u00eda, Pontificia Universidad Cat\u00f3lica de Chile Santiago Chile"},{"name":"Instituto de Ingenier\u00eda Biol\u00f3gica y M\u00e9dica, Pontificia Universidad Cat\u00f3lica de Chile Santiago Chile"},{"name":"Millenium Institute for Intelligent Healthcare Engineering iHEALTH Santiago Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,2,9]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.02.015"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12968-020-00607-1"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu281"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/HCI.0000000000000075"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/1532-429X-17-S1-P396"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/1532-429X-11-10"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2012.02.048"},{"issue":"1","key":"e_1_2_6_9_1","first-page":"157","article-title":"Impact of wall thickness and saccular geometry on the computational wall stress of descending thoracic aortic aneurysms","volume":"128","author":"Shang EK","year":"2013","journal-title":"Circulation"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2013.11.065"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi037"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-015-3906-x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2021.109573"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mri.2020.12.003"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41747-019-0107-4"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12968-020-00697-x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12968-021-00839-9"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/10976640600843413"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.24142"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.22049"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12968-016-0237-2"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mri.2015.10.002"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12968-019-0571-2"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.27734"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.23027"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.24602"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.27354"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.26274"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.20656"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.27694"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.21697"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2013.03.014"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1186\/1532-429X-13-71"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jet263"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mri.2019.08.017"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12968-021-00788-3"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.28275"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.29217"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mri.2022.01.007"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.27399"}],"container-title":["Journal of Magnetic Resonance Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmri.28613","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jmri.28613","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmri.28613","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T15:59:28Z","timestamp":1764691168000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmri.28613"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,9]]},"references-count":39,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["10.1002\/jmri.28613"],"URL":"https:\/\/doi.org\/10.1002\/jmri.28613","archive":["Portico"],"relation":{},"ISSN":["1053-1807","1522-2586"],"issn-type":[{"value":"1053-1807","type":"print"},{"value":"1522-2586","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,9]]},"assertion":[{"value":"2022-09-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}