{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T12:46:42Z","timestamp":1760014002961,"version":"3.40.5"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,3,5]],"date-time":"2023-03-05T00:00:00Z","timestamp":1677974400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The prevalence of abnormal cardiac magnetic resonance imaging (MRI) findings indicative of myocardial injury in patients who recovered from coronavirus disease 2019 (COVID\u201019) is currently unclear, with a high variability in the reported prevalence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To assess the prevalence of myocardial injury after a COVID\u201019 infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Type<\/jats:title><jats:p>Prospective, bicentric study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects<\/jats:title><jats:p>Seventy consecutive patients who recovered from COVID\u201019 and were previously hospitalized. Mean age was 57\u2009years and 39% of the patients were female. Ten healthy controls and a comparator group of 75 nonischemic cardiomyopathy (NICM) patients were employed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Field Strength\/Sequence<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">1.5\u2010T<\/jats:styled-content>, steady\u2010state free precession (<jats:styled-content style=\"fixed-case\">SSFP<\/jats:styled-content>) gradient\u2010echo sequence, modified <jats:styled-content style=\"fixed-case\">Look\u2010Locker<\/jats:styled-content> inversion recovery sequence with balanced <jats:styled-content style=\"fixed-case\">SSFP<\/jats:styled-content> readout, <jats:styled-content style=\"fixed-case\">T2<\/jats:styled-content>\u2010prepared spiral readout sequence and a <jats:styled-content style=\"fixed-case\">T1<\/jats:styled-content>\u2010weighted inversion recovery fast gradient\u2010echo sequence was acquired ~4\u20135\u2009months after recovery from <jats:styled-content style=\"fixed-case\">COVID<\/jats:styled-content>\u201019.<\/jats:p><\/jats:sec><jats:sec><jats:title>Assessment<\/jats:title><jats:p>The SSFP sequence was utilized for the calculation of left and right ventricular volumes and ejection fractions (LVEF and RVEF) following manual endocardial contouring. T1 and T2 mapping was performed by pixel\u2010wise exponential fitting, and T1 and T2 values were computed by manual contouring of the left ventricular endocardial and epicardial walls. Late gadolinium enhancement (LGE) images were graded qualitatively as LGE present or absent.<\/jats:p><\/jats:sec><jats:sec><jats:title>Statistical Tests<\/jats:title><jats:p><jats:italic>T<\/jats:italic>\u2010tests and the <jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup> or Fisher's exact tests were used to compare continuous and categorical variables respectively between the COVID\u201019 and NICM groups. Inter\u2010rater agreement was evaluated by the intraclass correlation coefficient for continuous variables and Cohen's kappa test for LGE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Reduced RVEF occurred in 10%, LGE and elevated native T1 in 9%, reduced LVEF in 4%, and elevated T2 in 3% of COVID\u201019 patients, respectively. Patients with NICM had lower mean LVEF (41.6%\u2009\u00b1\u20096% vs. 60%\u2009\u00b1\u20097%), RVEF (46%\u2009\u00b1\u20095% vs. 61%\u2009\u00b1\u20099%), and a significantly higher prevalence of LGE (27% vs. 9%) when compared to those post\u2010COVID\u201019.<\/jats:p><\/jats:sec><jats:sec><jats:title>Data Conclusion<\/jats:title><jats:p>Abnormal cardiac MRI findings may show a low prevalence in patients who recovered from COVID\u201019 and were previously hospitalized.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>2<\/jats:p><\/jats:sec><jats:sec><jats:title>Technical Efficacy<\/jats:title><jats:p>Stage 2<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.28668","type":"journal-article","created":{"date-parts":[[2023,3,6]],"date-time":"2023-03-06T06:34:23Z","timestamp":1678084463000},"page":"1777-1784","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Low Prevalence of Late Myocardial Injury on Cardiac <scp>MRI<\/scp> Following <scp>COVID<\/scp>\u201019 Infection"],"prefix":"10.1002","volume":"58","author":[{"given":"Ady","family":"Orbach","sequence":"first","affiliation":[{"name":"Schulich Heart Program Sunnybrook Health Science Center  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nilesh R.","family":"Ghugre","sequence":"additional","affiliation":[{"name":"Schulich Heart Program Sunnybrook Health Science Center  Toronto Ontario Canada"},{"name":"Physical Sciences Platform Sunnybrook Research Institute  Toronto Ontario Canada"},{"name":"Department of Medical Biophysics University of Toronto  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Labonny","family":"Biswas","sequence":"additional","affiliation":[{"name":"Schulich Heart Program Sunnybrook Health Science Center  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kim A.","family":"Connelly","sequence":"additional","affiliation":[{"name":"Division of Cardiology St Michael's Hospital  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrienne","family":"Chan","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Sunnybrook Health Science Centre  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bradley H.","family":"Strauss","sequence":"additional","affiliation":[{"name":"Schulich Heart Program Sunnybrook Health Science Center  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graham A.","family":"Wright","sequence":"additional","affiliation":[{"name":"Schulich Heart Program Sunnybrook Health Science Center  Toronto Ontario Canada"},{"name":"Physical Sciences Platform Sunnybrook Research Institute  Toronto Ontario Canada"},{"name":"Department of Medical Biophysics University of Toronto  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4058-4085","authenticated-orcid":false,"given":"Idan","family":"Roifman","sequence":"additional","affiliation":[{"name":"Schulich Heart Program Sunnybrook Health Science Center  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,3,5]]},"reference":[{"unstructured":"Johns Hopkins Coronavirus Resource Center.2022. 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