{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T16:58:05Z","timestamp":1792083485563,"version":"4.4.0"},"reference-count":106,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T00:00:00Z","timestamp":1680480000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["pericles.pericles-gcp.literatumonline.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:sec><jats:label\/><jats:p>Cranio\u2010spinal volume and pressure changes associated with the cardiac\u2010cycle and respiration are altered in Chiari I malformation (CMI) due to obstruction of cerebrospinal fluid (CSF) flow at the foramen magnum. With the introduction of motion\u2010sensitive MRI sequences, it was envisioned that these could provide noninvasive information about volume\u2013pressure dynamics at the cranio\u2010cervical junction in CMI hitherto available only through invasive pressure measurements. Since the early 1990s, multiple studies have assessed CSF flow and brain motion in CMI. However, differences in design and varied approaches in the presentation of results and conclusions makes it difficult to fully comprehend the role of MR imaging of CSF flow and brain motion in CMI. In this review, a cohesive summary of the current status of MRI assessment of CSF flow and brain motion in CMI is presented. Simplified versions of the results and conclusions of previous studies are presented by dividing the studies in distinct topics: 1) comparing CSF flow and brain motion between healthy subjects (HS) and CMI patients (before and after surgery), 2) comparing CSF flow and brain motion to CMI severity and symptoms, and 3) comparing CSF flow and brain motion in CMI with and without syringomyelia. Finally, we will discuss our vision of the future directions of MR imaging in CMI patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Evidence Level<\/jats:title><jats:p>2.<\/jats:p><\/jats:sec><jats:sec><jats:title>Technical Efficacy<\/jats:title><jats:p>5.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.28717","type":"journal-article","created":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T06:52:59Z","timestamp":1680591179000},"page":"360-378","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Cerebrospinal Fluid Flow and Brain Motion in Chiari I Malformation: Past, Present, and Future"],"prefix":"10.1002","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1952-9732","authenticated-orcid":false,"given":"Rafeeque A.","family":"Bhadelia","sequence":"first","affiliation":[{"name":"Department of Radiology, Beth Israel Deaconess Medical Center Harvard Medical School  Boston Massachusetts 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