{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T07:20:48Z","timestamp":1768720848833,"version":"3.49.0"},"reference-count":38,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,6,14]],"date-time":"2023-06-14T00:00:00Z","timestamp":1686700800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The societal cost of shoulder disabilities in our aging society keeps rising. Providing biomarkers of early changes in the microstructure of rotator cuff (RC) muscles might improve surgical planning. Elevation angle (E1A) and pennation angle (PA) assessed by ultrasound change with RC tears. Furthermore, ultrasounds lack repeatability.<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To propose a repeatable framework to quantify the myocyte angulation in RC muscles.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Type<\/jats:title><jats:p>Prospective.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects<\/jats:title><jats:p>Six asymptomatic healthy volunteers (1 female aged 30\u2009years; 5 males, mean age 35\u2009years, range 25\u201349\u2009years), who underwent three repositioned scanning sessions (10\u2009minutes apart) of the right infraspinatus muscle (ISPM) and supraspinatus muscle (SSPM).<\/jats:p><\/jats:sec><jats:sec><jats:title>Field Strength\/Sequence<\/jats:title><jats:p>3\u2010T, T1\u2010weighted and diffusion tensor imaging (DTI; 12 gradient encoding directions, <jats:italic>b<\/jats:italic>\u2010values of 500 and 800\u2009s\/mm<jats:sup>2<\/jats:sup>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Assessment<\/jats:title><jats:p>Each voxel was binned in percentage of depth defined by the shortest distance in the antero\u2010posterior direction (manual delineation), i.e. the radial axis. A second order polynomial fit for PA across the muscle depth was used, while E1A described a sigmoid across depth: .<\/jats:p><\/jats:sec><jats:sec><jats:title>Statistical Tests<\/jats:title><jats:p>Repeatability was assessed with the nonparametric Wilcoxon's rank\u2010sum test for paired comparisons across repeated scans in each volunteer for each anatomical muscle region and across repeated measures of the radial axis. A <jats:italic>P<\/jats:italic>\u2010value &lt;0.05 was considered statistically significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the ISPM, E1A was constantly negative, became helicoidal, then mainly positive across the antero\u2010posterior depth, respective at the caudal, central and cranial regions. In the SSPM, posterior myocytes ran more parallel to the intramuscular tendon (), while anterior myocytes inserted with a pennation angle (). E1A and PA were repeatable in each volunteer (error\u2009&lt;\u200910%). Intra\u2010repeatability of the radial axis was achieved (error\u2009&lt;\u20095%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Data Conclusion<\/jats:title><jats:p>ElA and PA in the proposed framework of the ISPM and SSPM are repeatable with DTI. Variations of myocyte angulation in the ISPM and SSPM can be quantified across volunteers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Evidence Level<\/jats:title><jats:p>2<\/jats:p><\/jats:sec><jats:sec><jats:title>Technical Efficacy<\/jats:title><jats:p>Stage 2<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.28840","type":"journal-article","created":{"date-parts":[[2023,6,15]],"date-time":"2023-06-15T03:30:07Z","timestamp":1686799807000},"page":"851-862","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Characterizing the Myoarchitecture of the Supraspinatus and Infraspinatus Muscles With <scp>MRI<\/scp> Using Diffusion Tensor Imaging"],"prefix":"10.1002","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2664-5272","authenticated-orcid":false,"given":"Cyril","family":"Tous","sequence":"first","affiliation":[{"name":"Research Center, Centre hospitalier de l'Universit\u00e9 de Montr\u00e9al (CRCHUM)  Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandre","family":"Jodoin","sequence":"additional","affiliation":[{"name":"Department of Radiology Centre hospitalier de l'Universit\u00e9 de Montr\u00e9al (CHUM)  Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5455-1727","authenticated-orcid":false,"given":"Beau","family":"Pontr\u00e9","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Medical Imaging University of Auckland  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5518-5917","authenticated-orcid":false,"given":"Detlev","family":"Grabs","sequence":"additional","affiliation":[{"name":"Department of Anatomy Universit\u00e9 du Qu\u00e9bec \u00e0 Trois\u2010Rivi\u00e8res  Trois\u2010Rivi\u00e8res Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4107-9160","authenticated-orcid":false,"given":"Mikael","family":"Begon","sequence":"additional","affiliation":[{"name":"\u00c9cole de kin\u00e9siologie et des sciences de l'activit\u00e9 physique Centre d'\u00e9ducation physique et des sports de l'Universit\u00e9 de Montr\u00e9al  Montr\u00e9al Qu\u00e9bec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3710-9280","authenticated-orcid":false,"given":"Nathalie J.","family":"Bureau","sequence":"additional","affiliation":[{"name":"Research Center, Centre hospitalier de l'Universit\u00e9 de Montr\u00e9al (CRCHUM)  Montreal Quebec Canada"},{"name":"Department of Radiology Centre hospitalier de l'Universit\u00e9 de Montr\u00e9al (CHUM)  Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6565-8469","authenticated-orcid":false,"given":"Elijah","family":"Van Houten","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering Universit\u00e9 de Sherbrooke  Sherbrooke Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,6,14]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.csm.2012.07.001"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00276-011-0872-0"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.18.19776"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ca.20469"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.28424"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546514529644"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/RCT.0000000000000740"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546506297539"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/564825"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jse.2018.10.021"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jse.2011.01.005"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00776-011-0176-6"},{"issue":"8","key":"e_1_2_9_14_1","first-page":"1021","article-title":"Fiber type composition of the architecturally distinct regions of human supraspinatus muscle: A cadaveric study","volume":"28","author":"Kim S","year":"2013","journal-title":"Histol Histopathol"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.083923"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1080\/10255842.2014.917294"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00276-016-1707-9"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546520988688"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2021.04.039"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/03635465221083325"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1159\/000016784"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1067\/mse.2000.108387"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/ca.20896"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhsa.2011.01.008"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelekin.2006.04.011"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.01430.2011"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0157273"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2016.03.005"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12968-020-00662-8"},{"key":"e_1_2_9_30_1","unstructured":"ColomboNM.Numerical modelling of ventricular mechanics: Role of the myofibre architecture.2014."},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.media.2006.04.001"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0241996"},{"issue":"6","key":"e_1_2_9_33_1","first-page":"H2308","article-title":"Histological validation of myocardial microstructure obtained from diffusion tensor magnetic resonance imaging","volume":"275","author":"Scollan DF","year":"1998","journal-title":"Am J Physiol"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.6009\/jjrt.2018_JSRT_74.4.335"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2006.01.015"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(94)80775-1"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1186\/1532-429X-14-49"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsams.2014.05.007"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1109\/TBME.2018.2872833"}],"container-title":["Journal of Magnetic Resonance Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmri.28840","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T13:00:21Z","timestamp":1707310821000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmri.28840"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,14]]},"references-count":38,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["10.1002\/jmri.28840"],"URL":"https:\/\/doi.org\/10.1002\/jmri.28840","archive":["Portico"],"relation":{},"ISSN":["1053-1807","1522-2586"],"issn-type":[{"value":"1053-1807","type":"print"},{"value":"1522-2586","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,14]]},"assertion":[{"value":"2022-12-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-06-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}