{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T04:28:18Z","timestamp":1771475298536,"version":"3.50.1"},"reference-count":40,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T00:00:00Z","timestamp":1702598400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>MR elastography (MRE) may provide quantitative imaging biomarkers of lumbar back muscles (LBMs), complementing MRI in spinal diseases by assessing muscle mechanical properties. However, reproducibility analyses for MRE of LBM are lacking.<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To assess technical failure, within\u2010day and inter\u2010day reproducibility, robustness with the excitation source positioning, and inter\u2010observer agreement of MRE of muscles.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Type<\/jats:title><jats:p>Prospective.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects<\/jats:title><jats:p>Seventeen healthy subjects (mean age 28\u2009\u00b1\u20094\u2009years; 11 females).<\/jats:p><\/jats:sec><jats:sec><jats:title>Field Strength\/Sequence<\/jats:title><jats:p>1.5\u2009T, gradient\u2010echo MRE, T1\u2010weighted turbo spin echo.<\/jats:p><\/jats:sec><jats:sec><jats:title>Assessment<\/jats:title><jats:p>The pneumatic driver was centered at L3 level. Four MRE were performed during two visits, 2\u20134\u2009weeks apart, each consisting of two MRE with less than 10\u2009minutes inter\u2010scan interval. At Visit 1, after the first MRE, the coil and driver were removed, then reinstalled. The MRE was repeated. At Visit 2, following the first MRE, only the driver was moved down 5\u2009cm. The MRE was repeated. Two radiologists segmented the multifidus and erector spinae muscles.<\/jats:p><\/jats:sec><jats:sec><jats:title>Statistical Tests<\/jats:title><jats:p>Paired <jats:italic>t<\/jats:italic>\u2010test, analysis of variance, intraclass correlation coefficients (ICCs). <jats:italic>P<\/jats:italic>\u2010values &lt;0.05 were considered statistically significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean stiffness of LBM ranged from 1.44 to 1.60\u2009kPa. Mean technical failure rate was 2.5%. Inter\u2010observer agreement was excellent (ICC ranging from 0.82 [0.64\u20130.96] to 0.99 [0.98\u20130.99] in the multifidus, and from 0.85 [0.69\u20130.92] to 0.99 [0.97\u20130.99] in the erector spinae muscles). Within\u2010day reproducibility was fair in the multifidus (ICC: 0.53 [0.47\u20130.77]) and good in the erector spinae muscles (ICC: 0.74 [0.48\u20130.88]). Reproducibility after moving the driver was excellent in both multifidus (ICC: 0.85 [0.69\u20130.93]) and erector spinae muscles (ICC: 0.84 [0.67\u20130.92]). Inter\u2010day reproducibility was excellent in the multifidus (ICC: 0.76 [0.48\u20130.89]) and poor in the erector spinae muscles (ICC: 0.23 [\u22120.61 to 0.63]).<\/jats:p><\/jats:sec><jats:sec><jats:title>Data Conclusion<\/jats:title><jats:p>MRE of LBM provides measurements of stiffness with fair to excellent reproducibility and excellent inter\u2010observer agreement. However, inter\u2010day reproducibility in the multifidus muscles indicated that the herein used MRE protocol may not be optimal for this muscle.<\/jats:p><\/jats:sec><jats:sec><jats:title>Evidence Level<\/jats:title><jats:p>2<\/jats:p><\/jats:sec><jats:sec><jats:title>Technical Efficacy<\/jats:title><jats:p>Stage 1<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.29178","type":"journal-article","created":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T18:50:52Z","timestamp":1702666252000},"page":"1037-1048","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Evaluation of the Reproducibility of MR Elastography Measurements of the Lumbar Back Muscles"],"prefix":"10.1002","volume":"60","author":[{"given":"Benjamin","family":"Chevalier","sequence":"first","affiliation":[{"name":"Department of Radiology Cochin Hospital, Universit\u00e9 Paris Cit\u00e9, APHP  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dina","family":"Bedretdinova","sequence":"additional","affiliation":[{"name":"Center for Research in Epidemiology and StatisticS (CRESS) Universit\u00e9 Paris Cit\u00e9 and Universit\u00e9 Sorbonne Paris Nord, Inserm, INRAE  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire","family":"Pellot\u2010Barakat","sequence":"additional","affiliation":[{"name":"Laboratoire d'Imagerie Biom\u00e9dicale Multimodale, BIOMAPS Universit\u00e9 Paris\u2010Saclay, Service Hospitalier Frederic Joliot  Orsay France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xavier","family":"Ma\u00eetre","sequence":"additional","affiliation":[{"name":"Laboratoire d'Imagerie Biom\u00e9dicale Multimodale, BIOMAPS Universit\u00e9 Paris\u2010Saclay, Service Hospitalier Frederic Joliot  Orsay France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5753-9096","authenticated-orcid":false,"given":"Maud","family":"Creze","sequence":"additional","affiliation":[{"name":"Laboratoire d'Imagerie Biom\u00e9dicale Multimodale, BIOMAPS Universit\u00e9 Paris\u2010Saclay, Service Hospitalier Frederic Joliot  Orsay France"},{"name":"Department of Radiology Bic\u00eatre Hospital, Universit\u00e9 Paris\u2010Saclay, APHP  Le Kremlin Bic\u00eatre France"},{"name":"Arts et M\u00e9tiers Institute of Technology, Universit\u00e9 Sorbonne Paris Nord, IBHGC \u2013 Institut de Biom\u00e9canique Humaine Georges Charpak, HESAM Universit\u00e9  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,12,15]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60610-7"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.09.4134"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2023.09.002"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiomech.2017.09.008"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.msksp.2019.102078"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1050-6411(03)00044-0"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.28690"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/55\/21\/007"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9290(03)00005-8"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/1522-2586(200102)13:2<269::AID-JMRI1039>3.0.CO;2-1"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1053\/apmr.2002.35472"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21923"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.21073"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.4103\/1673-5374.313060"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2015.09.019"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.26281"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.23731"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2010.02.013"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00256-017-2843-y"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/10669817.2021.1977069"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/45\/6\/313"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-021-03324-0"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mri.2019.08.006"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0214812"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00276-018-2087-0"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.20817"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1080\/10255842.2014.931086"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/ca.23065"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics12061385"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2016160863"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/joa.12978"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0124311"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiomech.2019.01.010"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/jum.15092"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mri.2020.04.009"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2012.01.017"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.4543"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1088\/1361-6560\/aa9164"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.20487"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.21307"}],"container-title":["Journal of Magnetic Resonance Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmri.29178","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T16:17:25Z","timestamp":1722529045000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmri.29178"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,15]]},"references-count":40,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["10.1002\/jmri.29178"],"URL":"https:\/\/doi.org\/10.1002\/jmri.29178","archive":["Portico"],"relation":{},"ISSN":["1053-1807","1522-2586"],"issn-type":[{"value":"1053-1807","type":"print"},{"value":"1522-2586","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,15]]},"assertion":[{"value":"2023-09-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}