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The relationship between the total cerebral\n                      <jats:italic>Q<\/jats:italic>\n                      and sex and age was also assessed. Twelve volunteers underwent two scans within a month.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Statistical Tests<\/jats:title>\n                    <jats:p>\n                      The intraclass correlation coefficient (ICC) evaluated the inter\u2010observer agreement. Blood flow parameters among volunteers were compared by the independent\u2010sample\n                      <jats:italic>t<\/jats:italic>\n                      \u2010test or Mann\u2013Whitney\n                      <jats:italic>U<\/jats:italic>\n                      test. The multiple linear regression equation was used to evaluate the relationship between total cerebral\n                      <jats:italic>Q<\/jats:italic>\n                      and age and sex.\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.05 indicated statistical significance.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The test\u2013retest and interobserver reliability of average velocity and\n                      <jats:italic>Q<\/jats:italic>\n                      were moderate to high (ICC: 0.54\u20130.99). Cerebral sinus velocity varied by segment and cardiac cycle. The SSS's velocity and\n                      <jats:italic>Q<\/jats:italic>\n                      increased downstream and\n                      <jats:italic>Q<\/jats:italic>\n                      near torcular herophili was 3.5 times that through the STS. The total cerebral\n                      <jats:italic>Q<\/jats:italic>\n                      decreased by 0.06\u2009mL\/s per year (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u2009\u22120.06\u2009\u00b1\u20090.013) and was sex\u2010independent within the group. Vortexes were found in 12.12%, 8.9%, and 59.8% of torcular herophili, transverse\u2010sigmoid junction, and jugular bulb, respectively, and were related to higher upstream flow.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Conclusion<\/jats:title>\n                    <jats:p>Cerebral sinuses could be measured visually and quantitatively in vivo by 4D Flow MRI, providing a basis for future research on pulsating tinnitus, multiple sclerosis, and other related diseases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Evidence Level<\/jats:title>\n                    <jats:p>2<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Technical Efficacy<\/jats:title>\n                    <jats:p>Stage 1<\/jats:p>\n                  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