{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T21:30:38Z","timestamp":1793136638421,"version":"4.5.0"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T00:00:00Z","timestamp":1723593600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01HL127153"],"award-info":[{"award-number":["R01HL127153"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The rotating Cartesian k\u2010space multiphase steady\u2010state imaging with contrast (ROCK\u2010MUSIC) pulse sequence enables acquisition of whole\u2010heart, cardiac phase\u2010resolved images in pediatric congenital heart disease (CHD) without reliance on the ventilator gating signal. Multidimensional reconstruction with low rank tensor (LRT) has shown promise for resolving complex cardiorespiratory motion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To enhance ROCK\u2010MUSIC by resolving cardiorespiratory phases using LRT reconstruction and to enable semi\u2010automatic hyperparameter tuning by developing an image quality scoring model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Type<\/jats:title><jats:p>Retrospective.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>Thirty patients (45% female, age 2\u2009days to 6.7\u2009years) with CHD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Field Strength\/Sequence<\/jats:title><jats:p>3\u2010T, four\u2010dimensional (4D) spoiled gradient recalled echo sequence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Assessment<\/jats:title><jats:p>Eigenvector\u2010based iTerative Self\u2010consistent Parallel Imaging Reconstruction (ESPIRiT) served as the reference comparison for LRT reconstruction. A 4\u2010point Likert scale was used for cardiac and vascular image quality scoring based on cardiac chamber definition, lumen signal uniformity, vascular margin clarity, and motion artifact. Ejection fraction and ventricular volumes were assessed in 16 patients. Signal\u2010to\u2010noise ratio (SNR), contrast\u2010to\u2010noise ratio (CNR), and edge sharpness were computed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Statistical Tests<\/jats:title><jats:p>Intraclass correlation coefficients, Wilcoxon signed\u2010rank test, Bland\u2013Altman. A <jats:italic>P<\/jats:italic>\u2010value &lt;0.05 was considered statistically significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Relative to ESPIRiT, LRT images received significantly higher cardiac (2.81\u2009\u00b1\u20090.57 vs. 3.19\u2009\u00b1\u20090.54) and vascular (2.81\u2009\u00b1\u20090.60 vs. 3.36\u2009\u00b1\u20090.53) image quality scores. Image quality scoring with semi\u2010automated hyperparameter tuning showed strong correlations (<jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u20090.748) among image quality, SNR, and septal sharpness. Comparison of ejection fraction and volumetry derived from ESPIRiT, and LRT showed no significant systematic difference (<jats:italic>P<\/jats:italic>\u2009=\u20090.32).<\/jats:p><\/jats:sec><jats:sec><jats:title>Data Conclusion<\/jats:title><jats:p>Integration of low\u2010rank reconstruction with ROCK\u2010MUSIC acquisition may be feasible, and semi\u2010automatic hyperparameter tuning could be effective for generating cardiorespiratory resolved images.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>2<\/jats:p><\/jats:sec><jats:sec><jats:title>Technical Efficacy<\/jats:title><jats:p>Stage 1<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.29565","type":"journal-article","created":{"date-parts":[[2024,8,15]],"date-time":"2024-08-15T06:13:05Z","timestamp":1723702385000},"page":"1311-1322","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Ferumoxytol\u2010Enhanced <scp>5D<\/scp> Multiphase Steady\u2010State Imaging Using Rotating Cartesian K\u2010Space With Low\u2010Rank Reconstruction for Pediatric Congenital Heart Disease"],"prefix":"10.1002","volume":"61","author":[{"given":"Zixuan","family":"Zhao","sequence":"first","affiliation":[{"name":"Physics and Biology in Medicine Graduate Program David Geffen School of Medicine at UCLA  Los Angeles California USA"},{"name":"Division of Cardiology David Geffen School of Medicine at UCLA, VA Greater Los Angeles Healthcare System  Los Angeles California USA"},{"name":"Department of Radiological Sciences David Geffen School of Medicine at UCLA  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsu\u2010Lei","family":"Lee","sequence":"additional","affiliation":[{"name":"Biomedical Imaging Research Institute Cedars\u2010Sinai Medical Center  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Ruan","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology David Geffen School of Medicine at UCLA  Los Angeles California USA"},{"name":"Department of Bioengineering University of California, Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengyang","family":"Ming","sequence":"additional","affiliation":[{"name":"Physics and Biology in Medicine Graduate Program David Geffen School of Medicine at UCLA  Los Angeles California USA"},{"name":"Department of Radiological Sciences David Geffen School of Medicine at UCLA  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Han","sequence":"additional","affiliation":[{"name":"Siemens Medical Solutions  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arash","family":"Bedayat","sequence":"additional","affiliation":[{"name":"Department of Radiological Sciences David Geffen School of Medicine at UCLA  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9334-8684","authenticated-orcid":false,"given":"Anthony G.","family":"Christodoulou","sequence":"additional","affiliation":[{"name":"Department of Radiological Sciences David Geffen School of Medicine at UCLA  Los Angeles California USA"},{"name":"Biomedical Imaging Research Institute Cedars\u2010Sinai Medical Center  Los Angeles California USA"},{"name":"Department of Bioengineering University of California, Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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