{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:49:52Z","timestamp":1786978192624,"version":"build-2736575974"},"reference-count":31,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,10,10]],"date-time":"2024-10-10T00:00:00Z","timestamp":1728518400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001273","name":"CHILDREN with CANCER UK","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001273","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2025,4]]},"abstract":"\n Background<\/jats:title>\n Diffusion\u2010weighted imaging (DWI) is routinely used in brain tumor surgery guided by intraoperative MRI (IoMRI). However, conventional echo planar imaging DWI (EPI\u2010DWI) is susceptible to distortion and artifacts that affect image quality. Turbo spin echo DWI (TSE\u2010DWI) is an alternative technique with minimal spatial distortions that has the potential to be the radiologically preferred sequence.<\/jats:p>\n <\/jats:sec>\n \n Purpose<\/jats:title>\n To compare via single\u2010 and multisequence assessment EPI\u2010DWI and TSE\u2010DWI in the IoMRI setting to determine whether there is a radiological preference for either sequence.<\/jats:p>\n <\/jats:sec>\n \n Study Type<\/jats:title>\n Retrospective.<\/jats:p>\n <\/jats:sec>\n \n Population<\/jats:title>\n Thirty\u2010four patients (22 female) aged 2\u201361\u2009years (24 under 18\u2009years) undergoing IoMRI during surgical resection of intracranial tumors.<\/jats:p>\n <\/jats:sec>\n \n Field Strength\/Sequence<\/jats:title>\n 3\u2010T, EPI\u2010DWI, and TSE\u2010DWI.<\/jats:p>\n <\/jats:sec>\n \n Assessment<\/jats:title>\n Patients were scanned with EPI\u2010 and TSE\u2010DWI as part of the standard IoMRI scanning protocol. A single\u2010sequence assessment of spatial distortion and image artifact was performed by three neuroradiologists blinded to the sequence type. Images were scored regarding distortion and artifacts, around and remote to the resection cavity. A multisequence radiological assessment was performed by three neuroradiologists in full radiological context including all other IoMRI sequences from each case. The DWI images were directly compared with scorings of the radiologists on which they preferred with respect to anatomy, abnormality, artifact, and overall preference.<\/jats:p>\n <\/jats:sec>\n \n Statistical Tests<\/jats:title>\n \n Wilcoxon signed\u2010rank tests for single\u2010sequence assessment, weighted kappa for single and multisequence assessment. A\n P<\/jats:italic>\n \u2010value <0.001 was considered statistically significant.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n For the blinded single\u2010sequence assessment, the TSE\u2010DWI sequence was scored equal to or superior to the EPI\u2010DWI sequence for distortion and artifacts, around and remote to the resection cavity for every case. In the multisequence assessment, all radiologists independently expressed a preference for TSE\u2010DWI over EPI\u2010DWI sequences on viewing brain anatomy, abnormalities, and artifacts.<\/jats:p>\n <\/jats:sec>\n \n Data Conclusion<\/jats:title>\n The TSE\u2010DWI sequences may be favored over EPI\u2010DWI for IoMRI in patients with intracranial tumors.<\/jats:p>\n <\/jats:sec>\n \n Level of Evidence<\/jats:title>\n 2<\/jats:p>\n <\/jats:sec>\n \n Technical Efficacy<\/jats:title>\n Stage 5<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/jmri.29614","type":"journal-article","created":{"date-parts":[[2024,10,10]],"date-time":"2024-10-10T21:48:49Z","timestamp":1728596929000},"page":"1847-1857","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Comparison of Echo Planar and Turbo Spin Echo Diffusion\u2010Weighted Imaging in Intraoperative\n MRI<\/scp>"],"prefix":"10.1002","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-8909-6453","authenticated-orcid":false,"given":"James C.","family":"Thorpe","sequence":"first","affiliation":[{"name":"Medical Physics and Clinical Engineering Nottingham University Hospitals Nottingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5136-6000","authenticated-orcid":false,"given":"Stefanie C.","family":"Thust","sequence":"additional","affiliation":[{"name":"Radiological Sciences Academic Unit of Mental Health and Clinical Neuroscience, School of Medicine, University of Nottingham Nottingham UK"},{"name":"NIHR Nottingham Biomedical Research Centre Nottingham UK"},{"name":"Department of Brain Rehabilitation and Repair UCL Institute of Neurology, Queen Square London UK"},{"name":"Sir Peter Mansfield Imaging Centre University of Nottingham Nottingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire H. M.","family":"Gillon","sequence":"additional","affiliation":[{"name":"Radiology Nottingham University Hospitals Nottingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8776-848X","authenticated-orcid":false,"given":"Selene","family":"Rowe","sequence":"additional","affiliation":[{"name":"Radiology Nottingham University Hospitals Nottingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-2015-850X","authenticated-orcid":false,"given":"Charlotte E.","family":"Swain","sequence":"additional","affiliation":[{"name":"Radiology Nottingham University Hospitals Nottingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4105-1846","authenticated-orcid":false,"given":"Donald C.","family":"MacArthur","sequence":"additional","affiliation":[{"name":"Neurosurgery Nottingham University Hospitals Nottingham UK"},{"name":"Children's Brain Tumour 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