{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T01:12:43Z","timestamp":1759972363687,"version":"build-2065373602"},"reference-count":40,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,6,29]],"date-time":"2025-06-29T00:00:00Z","timestamp":1751155200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100016926","name":"Kyoto University Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016926","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP22K07746","JP24K18796"],"award-info":[{"award-number":["JP22K07746","JP24K18796"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Vessel\u2010specific bolus arrival time (BAT) has become calculated with higher spatiotemporal resolution on dynamic contrast\u2010enhanced magnetic resonance imaging using the Golden\u2010angle RAdial Sparse Parallel (GRASP) technique. However, its utility in moyamoya disease (MMD) is unclear.<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To evaluate the relationship between BAT and arterial stenosis\/periventricular anastomosis (PA) development, and the utility of BAT in MMD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Type<\/jats:title><jats:p>Retrospective.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects<\/jats:title><jats:p>Sixty\u2010one preoperative MMD patients (mean\u2009\u00b1\u2009standard deviation age, 31.0\u2009\u00b1\u200920.4\u2009years; 46 females; 25 children).<\/jats:p><\/jats:sec><jats:sec><jats:title>Field Strength\/Sequence<\/jats:title><jats:p>3\u2010T, radial volume interpolated breath\u2010hold examination sequence, and three\u2010dimensional time\u2010of\u2010flight magnetic resonance angiography (3D TOF\u2010MRA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Assessment<\/jats:title><jats:p>Arterial stenosis, including internal carotid artery, middle cerebral artery (MCA), and posterior cerebral artery, and PA development, including lenticulostriate artery, thalamic perforator, and choroidal channel, were scored on TOF\u2010MRA. Differences in BAT (\u0394BATs) between the right and left regions of interest (ROIs), including MCA M2, basal ganglia, thalamus, and choroid plexus, were compared with the right and left arterial stenosis score differences. \u0394BATs between the MCA M2 and the ipsilateral basal ganglia, thalamus, and choroid plexus were compared with PA scores. A logistic regression model including \u0394BAT was developed to assess the associations with recent transient ischemic attacks (TIAs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Statistical Tests<\/jats:title><jats:p>Kappa statistic, Friedman test, intraclass correlation coefficient, one\u2010way analysis of variance, Tukey\u2013Kramer test, logistic regression analysis, and receiver operating characteristic analysis. <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05 was considered significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>\u0394BATs between the right and left ROIs increased by 0.11\u20131.76\u2009s depending on arterial stenosis score differences. \u0394BATs between the MCA M2 and the ipsilateral ROIs decreased by 0.32\u20131.46\u2009s with higher PA scores. Models including \u0394BAT for recent TIAs showed areas under the curve of 0.81 in children and 0.78 in adults.<\/jats:p><\/jats:sec><jats:sec><jats:title>Data Conclusion<\/jats:title><jats:p>BAT was indicative of arterial stenosis and PA development, and was associated with recent TIAs in MMD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>3<\/jats:p><\/jats:sec><jats:sec><jats:title>Technical Efficacy<\/jats:title><jats:p>Stage 2<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.70006","type":"journal-article","created":{"date-parts":[[2025,7,13]],"date-time":"2025-07-13T12:14:31Z","timestamp":1752408871000},"page":"1321-1333","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Bolus Arrival Time on Dynamic Contrast\u2010Enhanced Magnetic Resonance Imaging Using the Golden\u2010Angle <scp>RAdial<\/scp> Sparse Parallel (<scp>GRASP<\/scp>) Technique: Characteristics and Clinical Utility in Moyamoya Disease"],"prefix":"10.1002","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5584-1072","authenticated-orcid":false,"given":"Shuichi","family":"Ito","sequence":"first","affiliation":[{"name":"Department of Diagnostic Imaging and Nuclear Medicine Kyoto University Graduate School of Medicine  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0831-195X","authenticated-orcid":false,"given":"Sachi","family":"Okuchi","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging and Nuclear Medicine Kyoto University Graduate School of Medicine  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1982-3168","authenticated-orcid":false,"given":"Yasutaka","family":"Fushimi","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging and Nuclear Medicine Kyoto University Graduate School of Medicine  Kyoto 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