{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T16:12:36Z","timestamp":1785255156887,"version":"3.55.0"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T00:00:00Z","timestamp":1759881600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T00:00:00Z","timestamp":1759881600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100007316","name":"Division of Cancer Prevention, National Cancer Institute","doi-asserted-by":"publisher","award":["W81XWH1910451"],"award-info":[{"award-number":["W81XWH1910451"]}],"id":[{"id":"10.13039\/100007316","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007316","name":"Division of Cancer Prevention, National Cancer Institute","doi-asserted-by":"publisher","award":["U10CA180868"],"award-info":[{"award-number":["U10CA180868"]}],"id":[{"id":"10.13039\/100007316","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007316","name":"Division of Cancer Prevention, National Cancer Institute","doi-asserted-by":"publisher","award":["U10CA180822"],"award-info":[{"award-number":["U10CA180822"]}],"id":[{"id":"10.13039\/100007316","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007316","name":"Division of Cancer Prevention, National Cancer Institute","doi-asserted-by":"publisher","award":["UG1CA189867"],"award-info":[{"award-number":["UG1CA189867"]}],"id":[{"id":"10.13039\/100007316","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007316","name":"Division of Cancer Prevention, National Cancer Institute","doi-asserted-by":"publisher","award":["U24CA180803"],"award-info":[{"award-number":["U24CA180803"]}],"id":[{"id":"10.13039\/100007316","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2026,2]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n Multi\u2010parametric MRI (mpMRI) datasets often vary between sites due to differences in acquisition protocols.<\/jats:p>\n <\/jats:sec>\n \n Purpose<\/jats:title>\n Evaluate adherence of multi\u2010site mpMRI dataset to minimum technical standards (MTS) of PI\u2010RADSv2.1.<\/jats:p>\n <\/jats:sec>\n \n Study Type<\/jats:title>\n Prospective.<\/jats:p>\n <\/jats:sec>\n \n Subjects<\/jats:title>\n Six hundred patients (Age (years): \u2264\u200949\u2009=\u20090.8%, 50\u201359\u2009=\u200910.7%, 60\u201369\u2009=\u200947.0%, \u2265\u200970\u2009=\u200941.5%) with intermediate\u2010risk prostate cancer (PCa) imaged across 124 institutions prior to radiotherapy.<\/jats:p>\n <\/jats:sec>\n \n Field Strength\/Sequence<\/jats:title>\n 3T, 1.5T, and 1.16T, T2\u2010weighted (T2w): fast spin\u2010echo, diffusion\u2010weighted imaging (DWI): single\u2010shot echo\u2010planar imaging, and dynamic contrast\u2010enhanced (DCE): T1\u2010weighted 3D fast spoiled gradient echo.<\/jats:p>\n <\/jats:sec>\n \n Assessment<\/jats:title>\n Scanner vendors included Siemens, GE, Philips, Toshiba, and Hitachi. Degree of adherence to PIRADSv2.1 was determined as the proportion of datasets that met MTS. Mean and standard deviation of parameter values were calculated where applicable. Prostate imaging quality (PI\u2010QUAL)v2 scores were assigned by one of three observers in 491 datasets. Evaluation of DICOM metadata consistency was performed.<\/jats:p>\n <\/jats:sec>\n \n Statistical Tests<\/jats:title>\n \n Fisher's exact test to assess changes in MTS adherence over time and by field strength; Harrel's C\u2010index to compare MTS adherence to PI\u2010QUAL score. A\n p<\/jats:italic>\n value of <\u20090.001 is considered statistically significant after Bonferroni correction.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Eighty\u2010two percent of MTS showed greater than 75% adherence. Low adherence was found in the in\u2010plane dimension (frequency\u2010encoding direction) for T2w images (57%, mean\u2009=\u20090.45\u2009\u00b1\u20090.16\u2009mm) and field of view (FOV) for DW images (62%, mean\u2009=\u200922.67\u2009\u00b1\u20094.70\u2009cm). Only 50% of datasets used the recommended high\n b<\/jats:italic>\n value image to compute the apparent diffusion coefficient map. Adherence improved significantly over time for one T2w and two DWI parameters; the adherence of FOV improved significantly at 3T for T2w and DWI sequences. C\u2010index values for two T2w and two DWI parameters demonstrated a relationship between PI\u2010RADS MTS and PI\u2010QUAL score. Ten percent of anonymized datasets were stripped of some sequence information.\n <\/jats:p>\n <\/jats:sec>\n \n Data Conclusion<\/jats:title>\n Results show promise for mpMRI standardization in characterization of PCa and identify key parameters that remain variable across datasets and institutions.<\/jats:p>\n <\/jats:sec>\n \n Evidence Level<\/jats:title>\n 1.<\/jats:p>\n <\/jats:sec>\n \n Technical Efficacy<\/jats:title>\n Stage 2.<\/jats:p>\n <\/jats:sec>\n \n Trial Registration<\/jats:title>\n \n ClinicalTrials.gov<\/jats:ext-link>\n : NCT03367702\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/jmri.70142","type":"journal-article","created":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T06:21:43Z","timestamp":1759990903000},"page":"464-474","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Assessing Quality and Adherence to\n PI<\/scp>\n \u2010\n RADSv2.1<\/scp>\n Minimum Technical Standards of Prostate\n MRI<\/scp>\n in\n NRG<\/scp>\n \u2010\n GU005<\/scp>"],"prefix":"10.1002","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2196-4565","authenticated-orcid":false,"given":"Stephanie","family":"Alley","sequence":"first","affiliation":[{"name":"Polytechnique Montr\u00e9al Montr\u00e9al Canada"},{"name":"CHUM\u2014Centre Hospitalier de l\u2019Universit\u00e9 de Montr\u00e9al Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion","family":"Tonneau","sequence":"additional","affiliation":[{"name":"CHUM\u2014Centre Hospitalier de l\u2019Universit\u00e9 de Montr\u00e9al Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damien","family":"Olivi\u00e9","sequence":"additional","affiliation":[{"name":"CHUM\u2014Centre Hospitalier de l\u2019Universit\u00e9 de Montr\u00e9al Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clare M.","family":"Tempany\u2010Afdhal","sequence":"additional","affiliation":[{"name":"Brigham and Women\u2019s Hospital Boston Massachusetts USA"},{"name":"Harvard Medical School Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter L.","family":"Choyke","sequence":"additional","affiliation":[{"name":"National Institutes of Health Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0853-6494","authenticated-orcid":false,"given":"I. Baris","family":"Turkbey","sequence":"additional","affiliation":[{"name":"National Cancer Institute, National Institutes of Health Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uulke A.","family":"van der Heide","sequence":"additional","affiliation":[{"name":"The Netherlands Cancer Institute Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodney J.","family":"Ellis","sequence":"additional","affiliation":[{"name":"GenesisCare USA Fort Myers Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Kadoury","sequence":"additional","affiliation":[{"name":"Polytechnique Montr\u00e9al Montr\u00e9al Canada"},{"name":"CHUM\u2014Centre Hospitalier de l\u2019Universit\u00e9 de Montr\u00e9al Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas P.","family":"Boike","sequence":"additional","affiliation":[{"name":"Michigan Healthcare Professionals Clarkston Accruals Under GenesisCare USA Farmington Hills Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Daniel","family":"Pennington","sequence":"additional","affiliation":[{"name":"Southeast Clinical Oncology Research Consortium NCORP Winston Salem North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur","family":"Frazier","sequence":"additional","affiliation":[{"name":"Karmanos Cancer Institute at McLaren Clarkston Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colleen A. 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