{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:38:24Z","timestamp":1790699904274,"version":"4.1.0"},"reference-count":37,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T00:00:00Z","timestamp":1762905600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T00:00:00Z","timestamp":1762905600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["NSFC 82371912"],"award-info":[{"award-number":["NSFC 82371912"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Biparametric MRI (bpMRI) is important for prostate cancer (PCa) diagnosis. Higher field strength at 5\u2009T may improve image quality versus 3\u2009T, but clinical value remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To compare image quality, imaging artifacts, and PCa visualization between 3\u2009T and 5\u2009T bpMRI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Type<\/jats:title>\n                    <jats:p>Prospective.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Population<\/jats:title>\n                    <jats:p>One hundred and five patients with clinically suspected PCa, including 56 with histologically proven prostatic lesions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Field Strength\/Sequence<\/jats:title>\n                    <jats:p>3\u2009T and 5\u2009T; T2\u2010weighted imaging (T2WI) using fast spin echo and echo\u2010planar diffusion\u2010weighted imaging (DWI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Assessment<\/jats:title>\n                    <jats:p>\n                      Signal\u2010to\u2010noise ratio (SNR) measured at both field strengths; in the biopsy\u2010proven cancer subset, contrast\u2010to\u2010noise ratio (CNR), apparent diffusion coefficient (ADC), and lesion\u2010boundary sharpness measured using the \u201cplot profile\u201d function. Image quality and lesion conspicuity rated on 5\u2010point Likert scales. Prostate imaging reporting and data system (PI\u2010RADS) v2.1 agreement was compared using Cohen\n                      <jats:italic>\u03ba<\/jats:italic>\n                      . Participants were grouped by pre\u2010scan enema (enema\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200961; non\u2010enema\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200944) for artifact comparisons.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Staistical Tests<\/jats:title>\n                    <jats:p>\n                      Wilcoxon signed\u2010rank test, ICC, and Cohen's\n                      <jats:italic>\u03ba<\/jats:italic>\n                      ;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05 was considered significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      5\u2009T demonstrated significantly higher SNR for T2WI (391.40 vs. 274.41) and DWI (208.82 vs. 106.40). CNR was higher at 5\u2009T for T2WI (median 10.3 vs. 8.5) and DWI (median 31.5 vs. 16.2); lesion\u2010edge sharpness was greater at 5\u2009T (median 48.1%\/mm vs. 30.9%\/mm). Median scores for image quality, lesion conspicuity, and anatomy visibility were higher at 5\u2009T than at 3\u2009T (4\u20135 vs. 3\u20134). DWI artifacts were more frequent at 5\u2009T in the non\u2010enema group (5\u2009T 20%\u201327% vs. 3\u2009T 11%\u201316%); other artifact comparisons were not significant (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.059\u20130.886). PI\u2010RADS scoring showed excellent inter\u2010reader agreement (\n                      <jats:italic>\u03ba<\/jats:italic>\n                      \u2009=\u20090.83\u20130.95) and good inter\u2010field agreement (\n                      <jats:italic>\u03ba<\/jats:italic>\n                      \u2009=\u20090.69\u20130.89).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Conclusion<\/jats:title>\n                    <jats:p>In bpMRI, 5\u2009T has significantly better T2WI and DWI image quality than 3\u2009T.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Evidence Level<\/jats:title>\n                    <jats:p>2.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Technical Efficacy<\/jats:title>\n                    <jats:p>Stage 3.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jmri.70171","type":"journal-article","created":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T10:50:07Z","timestamp":1762944607000},"page":"686-697","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Comparison of\n                    <scp>5\u2009T<\/scp>\n                    and\n                    <scp>3\u2009T<\/scp>\n                    Biparametric\n                    <scp>MRI<\/scp>\n                    for Clinically Suspected Prostate Cancer: Image Quality, Lesion Visualization, and Artifacts"],"prefix":"10.1002","volume":"63","author":[{"given":"Yunfeng","family":"Deng","sequence":"first","affiliation":[{"name":"Graduate School of Shanghai University of Traditional Chinese Medicine  Shanghai China"},{"name":"Department of Radiology, Renji Hospital, School of Medicine Shanghai Jiao Tong University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guiqin","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Renji Hospital, School of Medicine Shanghai Jiao Tong University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Chen","sequence":"additional","affiliation":[{"name":"Shanghai Second People's Hospital Shanghai Jiao Tong University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengyun","family":"He","sequence":"additional","affiliation":[{"name":"Department of Radiology, Renji Hospital, School of Medicine Shanghai Jiao Tong University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Lu","sequence":"additional","affiliation":[{"name":"United Imaging Healthcare Group  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaobin","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Radiology, Renji Hospital, School of Medicine Shanghai Jiao Tong University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingli","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Radiology, Renji Hospital, School of Medicine Shanghai Jiao Tong University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengying","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Renji Hospital, School of Medicine Shanghai Jiao Tong University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuansheng","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Radiology, Renji Hospital, School of Medicine Shanghai Jiao Tong University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinjie","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Urology, Renji Hospital, School of Medicine Shanghai Jiao Tong University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8195-6167","authenticated-orcid":false,"given":"Wei","family":"Xue","sequence":"additional","affiliation":[{"name":"Graduate School of Shanghai University of Traditional Chinese Medicine  Shanghai China"},{"name":"Department of Urology, Renji Hospital, School of Medicine Shanghai Jiao Tong University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-1789-9108","authenticated-orcid":false,"given":"Guangyu","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Renji Hospital, School of Medicine Shanghai Jiao Tong University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,12]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2020.09.042"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.15141412"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41585\u2010019\u20100212\u20104"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2019.02.033"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2024.09.035"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2019.05.029"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330\u2010005\u20102678\u20100"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/RLI.0000000000000342"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330\u2010014\u20103234\u20106"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2303021331"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.25723"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.29766"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13244\u2010022\u201001290\u20109"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.28097"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/mp.15970"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00261\u2010025\u201004954\u20104"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2020.10.019"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.230427"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14235741"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13244\u2010021\u201001063\u2010w"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2019"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2024.06.048"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000820"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.5466"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2282011860"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.233337"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.17.18516"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20191050"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.10819"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phro.2018.06.006"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD012663.pub2"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00261\u2010020\u201002600\u20109"},{"key":"e_1_2_8_34_1","unstructured":"\u201cMusculoskeletal MRI at 3.0 T and 7.0 T: A Comparison of Relaxation Times and Image Contrast\u2014PubMed \u201daccessed 24 Jun 2025 https:\/\/pubmed.ncbi.nlm.nih.gov\/22172536\/."},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2017.02.044"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1097\/RLI.0000000000001081"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1097\/RLI.0000000000001171"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.2967"}],"container-title":["Journal of Magnetic Resonance Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmri.70171","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jmri.70171","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmri.70171","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T05:49:50Z","timestamp":1770788990000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmri.70171"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,12]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1002\/jmri.70171"],"URL":"https:\/\/doi.org\/10.1002\/jmri.70171","archive":["Portico"],"relation":{},"ISSN":["1053-1807","1522-2586"],"issn-type":[{"value":"1053-1807","type":"print"},{"value":"1522-2586","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,12]]},"assertion":[{"value":"2025-08-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}