{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T11:02:16Z","timestamp":1780743736615,"version":"3.54.1"},"reference-count":48,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T00:00:00Z","timestamp":1771545600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T00:00:00Z","timestamp":1771545600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82101995"],"award-info":[{"award-number":["82101995"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82172053"],"award-info":[{"award-number":["82172053"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Ankle cartilage is prone to degeneration due to overuse. Developing a non\u2010invasive MRI technique to detect early running\u2010induced lesions enables timely intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the value of the ultrashort echo time magnetization transfer (UTE\u2010MT) sequence in monitoring tibiotalar cartilage changes in amateur marathon runners before and after a marathon.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Type<\/jats:title>\n                    <jats:p>Prospective.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects<\/jats:title>\n                    <jats:p>Thirty amateur marathon runners (25 males, 5 females; range: 24\u201350\u2009years).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Sequence<\/jats:title>\n                    <jats:p>3D UTE\u2010MT (gradient\u2010echo), 3D UTE\u2010T2* (gradient\u2010echo).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Assessment<\/jats:title>\n                    <jats:p>MRI scans at three time points: 1\u2009week pre\u2010marathon, 2\u2009days post\u2010marathon, and 4\u2009weeks post\u2010marathon. Medial and lateral tibiotalar cartilage was subdivided into 12 subregions, consisting of anterior, middle, and posterior segments for the tibial and talus parts on each side. The UTE\u2010MTR and UTE\u2010T2* values were measured per subregion at each time point.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Statistical Tests<\/jats:title>\n                    <jats:p>\n                      Repeated measures one\u2010way ANOVA and the Tukey test.\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05 was considered statistically significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Most cartilage subregions showed decreased UTE\u2010MTR values 2\u2009days post\u2010marathon and increased after 4\u2009weeks. Significant differences in UTE\u2010MTR over time were observed in 9 subregions, including the medial and lateral anterior, middle, and posterior tibial cartilage (MTiA, MTiM, MTiP, LTiA, LTiM, LTiP), the medial and lateral posterior talus regions (MTaP, LTaP), and the medial middle talus cartilage (MTaM). Post hoc tests revealed significant UTE\u2010MTR decreases 2\u2009days post\u2010marathon in all 9 regions (Rate: MTiA: \u22123.9%; MTiM: \u22122.8%; MTiP: \u22123.0%; MTaP: \u22124.5%; MTaM: \u22124.2%; LTiA: \u22123.5%; LTiM: \u22124.7%; LTiP: \u22125.8%; LTaP: \u22126.8%), with significant increases in MTiA (3.7%) and MTaM (4.4%) at 4\u2009weeks. UTE\u2010T2* values rose in most cartilage regions at 2\u2009days post\u2010marathon and continued increasing at 4\u2009weeks. Only MTiP, LTiM, and LTaM showed significant changes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Conclusion<\/jats:title>\n                    <jats:p>This study demonstrates that the UTE\u2010MT sequence enables the quantitative assessment of dynamic changes in tibiotalar joint cartilage after a marathon.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>2.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Technical Efficacy<\/jats:title>\n                    <jats:p>Stage 1.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jmri.70269","type":"journal-article","created":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T15:23:08Z","timestamp":1771600988000},"page":"1757-1766","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Ultrashort Echo Time Magnetization Transfer Imaging for Dynamic Monitoring of Ankle Cartilage After Long\u2010Distance Running"],"prefix":"10.1002","volume":"63","author":[{"given":"Yiyin","family":"Hu","sequence":"first","affiliation":[{"name":"Department of Radiology The Fifth Affiliated Hospital of Sun Yat\u2010Sen University  Zhuhai China"},{"name":"Guangdong Provincial Engineering Research Center of Molecular Imaging, Guangdong\u2010Hong Kong\u2010Macao University Joint Laboratory of Interventional Medicine, the Fifth Affiliated Hospital Sun Yat\u2010Sen University  Zhuhai Guangdong 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