{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,12]],"date-time":"2026-07-12T05:07:33Z","timestamp":1783832853800,"version":"3.55.0"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T00:00:00Z","timestamp":1778630400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T00:00:00Z","timestamp":1778630400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001711","name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","doi-asserted-by":"publisher","award":["P500PM_214180"],"award-info":[{"award-number":["P500PM_214180"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004362","name":"Schweizerische Herzstiftung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004362","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2026,8]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n Ebstein's anomaly (EA) is a congenital heart disorder involving tricuspid valve dysplasia and right heart abnormalities resulting in severe tricuspid regurgitation (TR). Multiple techniques assess regurgitation severity, but their correlation with EA severity markers remains unclear.<\/jats:p>\n <\/jats:sec>\n \n Purpose<\/jats:title>\n To compare MRI techniques for quantifying TR and regurgitant volume (RVol) in adults with EA.<\/jats:p>\n <\/jats:sec>\n \n Study Type<\/jats:title>\n Retrospective.<\/jats:p>\n <\/jats:sec>\n \n Subjects<\/jats:title>\n Thirty\u2010three adult patients with EA (15 males\/18 females).<\/jats:p>\n <\/jats:sec>\n \n Field Strength\/Sequence<\/jats:title>\n 3T or 1.5\u2010Tesla, 2D\u2010phase contrast (2D\u2010PC gradient echo) and 4D\u2010flow (gradient echo).<\/jats:p>\n <\/jats:sec>\n \n Assessment<\/jats:title>\n RVol was measured using three methods: (1) 2D\u2010indirect: subtraction of systolic pulmonary artery (PA) forward flow (2D\u2010PC) from functional right ventricular stroke volume (fRVSV); (2) 4D\u2010indirect: subtraction of PA systolic forward flow from tricuspid diastolic forward flow using 4D\u2010flow; (3) 4D\u2010direct: direct jet measurement with 4D\u2010flow. Correlations were evaluated between RVol and severity markers (left ventricular ejection fraction [LVEF], functional right ventricular end\u2010diastolic volume [fRVEDV], fRV\/LV ratio, severity index volume, total right\/left volume index, fRVEF).<\/jats:p>\n <\/jats:sec>\n \n Statistical Tests<\/jats:title>\n \n Pearson or Spearman correlation coefficients (\n p<\/jats:italic>\n \u2009<\u20090.05) significant.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The 4D\u2010direct method had the highest correlation with the mean RVol (2D\u2010indirect:\n r<\/jats:italic>\n \u2009=\u20090.93, 4D\u2010indirect:\n r<\/jats:italic>\n \u2009=\u20090.93; 4D\u2010direct:\n r<\/jats:italic>\n \u2009=\u20090.95) and with severity markers: total right\/left volume index (0.84, 0.64, 0.87), the fRVEDV (0.66, 0.58, 0.71), fRV\/LVratio (0.81, 0.75, 0.87), and severity index volume (0.45, 0.59, 0.66).\n <\/jats:p>\n <\/jats:sec>\n \n Data Conclusion<\/jats:title>\n 4D\u2010flow enables intrinsic RVol quantification independent of fRV segmentation, with the direct jet method outperforming indirect approaches.<\/jats:p>\n <\/jats:sec>\n \n Level of Evidence<\/jats:title>\n 3.<\/jats:p>\n <\/jats:sec>\n \n Technical Efficacy<\/jats:title>\n Stage 2.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/jmri.70339","type":"journal-article","created":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T11:49:56Z","timestamp":1778672996000},"page":"515-523","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Quantification of Tricuspid Valve Regurgitation With\n 2D<\/scp>\n and\n 4D<\/scp>\n \u2010Flow\n MRI<\/scp>\n : Comparison of Different Methods in Adult Patients With Ebstein's Anomaly"],"prefix":"10.1002","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2396-5062","authenticated-orcid":false,"given":"Eric","family":"Buffle","sequence":"first","affiliation":[{"name":"Universit\u00e9 Paris cit\u00e9, PARCC, INSERM Paris France"},{"name":"Radiology Department Assistance Publique H\u00f4pitaux de Paris, H\u00f4pital Europ\u00e9en Georges Pompidou Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathieu","family":"Albertini","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris cit\u00e9, PARCC, INSERM Paris France"},{"name":"Cardiology Department H\u00f4pital Europ\u00e9en Georges Pompidou, Assistance Publique\u2010H\u00f4pitaux de Paris Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1065-799X","authenticated-orcid":false,"given":"Damian","family":"Craiem","sequence":"additional","affiliation":[{"name":"Instituto de Medecina Traslacional, Trasplante y Bioingenieria (IMeTTyB), Universidad Favaloro\u2010CONICET Buenos Aires 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