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Agreement between measurements was evaluated with Bland\u2013Altman analysis including the bias and 95% limits of agreement.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Scan time for 5D (6:18 [0]) was significantly shorter than 2D (7:16 [4:39]) and 3D (6:55 [1:30]) MRI. 5D measurements were strongly correlated with 2D measurements of LVEDV (\n R<\/jats:italic>\n 2<\/jats:sup>\n \u2009=\u20090.94), LVESV (\n R<\/jats:italic>\n 2<\/jats:sup>\n \u2009=\u20090.83), LVEF (\n R<\/jats:italic>\n 2<\/jats:sup>\n \u2009=\u20090.51), (\n R<\/jats:italic>\n 2<\/jats:sup>\n \u2009=\u20090.85), RVESV (\n R<\/jats:italic>\n 2<\/jats:sup>\n \u2009=\u20090.80), and RVEF (\n R<\/jats:italic>\n 2<\/jats:sup>\n \u2009=\u20090.66) but with significant biases. Sharpness of the coronary arteries were significantly higher for 3D (RCA: 36.8%\u2009\u00b1\u200910.2%, LAD: 40.5%\u2009\u00b1\u200910.5%) than 5D (RCA: 24.3%\u2009\u00b1\u20097.5%, LAD: 31.7%\u2009\u00b1\u20098.7%), but longer vessel segments were visible using 5D (LAD: 6.9\u2009\u00b1\u20092.5) than 3D (LAD: 5.3\u2009\u00b1\u20092.9\u2009mm) acquisitions. The grades for 5D (R1: 3 [1], R2: 2.5 [0.5], R3: 3 [0.6]) were significantly higher than 3D (R1: 3 [1], R2: 2.5 [1], R3: 2 [1]).\n <\/jats:p>\n <\/jats:sec>\n \n Data Conclusion<\/jats:title>\n Gadolinium\u2010enhanced 5D MRI may provide an efficient and simplified acquisition for CHD patients, with multiple quantitative parameters from 5D being not significantly different from those from reference standard 2D and 3D MRI.<\/jats:p>\n <\/jats:sec>\n \n Evidence Level<\/jats:title>\n 4<\/jats:p>\n <\/jats:sec>\n \n Stage of Technical Efficacy<\/jats:title>\n 1<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/jmri.70402","type":"journal-article","created":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T13:35:17Z","timestamp":1782308117000},"page":"996-1008","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Performance of Free\u2010Running Cardiac and Respiratory Motion\u2010Resolved Whole\u2010Heart\n 5D MRI<\/scp>\n in Congenital Heart Disease Patients Using a Gadolinium Enhanced Fast\u2010Interrupted Steady\u2010State Sequence"],"prefix":"10.1002","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3111-8840","authenticated-orcid":false,"given":"Christopher W.","family":"Roy","sequence":"first","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology Lausanne University Hospital (CHUV) and University of Lausanne (UNIL) Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Vogeli","sequence":"additional","affiliation":[{"name":"Service of Cardiology Lausanne University Hospital (CHUV) and University of Lausanne (UNIL) Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alissia","family":"Megalo","sequence":"additional","affiliation":[{"name":"Service of Cardiology Lausanne University Hospital (CHUV) and University of Lausanne (UNIL) Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabienne","family":"Dirbach","sequence":"additional","affiliation":[{"name":"Service of Cardiology Lausanne University Hospital (CHUV) and University of Lausanne (UNIL) Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica A. M.","family":"Bastiaansen","sequence":"additional","affiliation":[{"name":"Department of Diagnostic, Interventional and Pediatric Radiology (DIPR), Inselspital Bern University Hospital Switzerland"},{"name":"Translational Imaging Center (TIC) Swiss Institute for Translational and Entrepreneurial Medicine Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4347-8613","authenticated-orcid":false,"given":"J\u00e9r\u00f4me","family":"Yerly","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology Lausanne University Hospital (CHUV) and University of Lausanne (UNIL) Lausanne Switzerland"},{"name":"Center for Biomedical Imaging (CIBM) Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Mueller","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology Lausanne University Hospital (CHUV) and University of Lausanne (UNIL) Lausanne Switzerland"},{"name":"Swiss Innovation Hub Siemens Healthineers International AG Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology Lausanne University Hospital (CHUV) and University of Lausanne (UNIL) Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0447-5073","authenticated-orcid":false,"given":"Jean\u2010Baptiste","family":"Ledoux","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology Lausanne University Hospital (CHUV) and University of Lausanne (UNIL) Lausanne Switzerland"},{"name":"Center for Biomedical Imaging (CIBM) Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9966-6149","authenticated-orcid":false,"given":"Juerg","family":"Schwitter","sequence":"additional","affiliation":[{"name":"Service of Cardiology Lausanne University Hospital (CHUV) and University of Lausanne (UNIL) Lausanne Switzerland"},{"name":"Cardiac MRI Center of the University Hospital Lausanne (CRMC) Lausanne University Hospital (CHUV) Lausanne Switzerland"},{"name":"Interventional MRI Center of the University Hospital Lausanne Lausanne University Hospital (CHUV) Lausanne Switzerland"},{"name":"Faculty of Biology and Medicine University of Lausanne (UNIL) Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9483-7957","authenticated-orcid":false,"given":"Milan","family":"Pr\u0161a","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology, Mother\u2010Woman\u2010Child Department Lausanne University Hospital (CHUV) and University of Lausanne (UNIL) Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0994-3964","authenticated-orcid":false,"given":"Estelle","family":"Tenisch","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology Lausanne University Hospital (CHUV) and University of Lausanne (UNIL) Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5899-291X","authenticated-orcid":false,"given":"Tobias","family":"Rutz","sequence":"additional","affiliation":[{"name":"Service of Cardiology Lausanne University Hospital (CHUV) and University of Lausanne (UNIL) Lausanne Switzerland"},{"name":"Cardiac MRI Center of the University Hospital Lausanne (CRMC) Lausanne University Hospital (CHUV) Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9843-2028","authenticated-orcid":false,"given":"Matthias","family":"Stuber","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology Lausanne University Hospital (CHUV) and University of Lausanne (UNIL) Lausanne Switzerland"},{"name":"Center for Biomedical Imaging (CIBM) Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,24]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12968-022-00873-1"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1532-429X-15-51"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9592.2004.01221.x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.27898"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12968-022-00871-3"},{"key":"e_1_2_9_7_1","article-title":"Free\u2010Running 5D Whole\u2010Heart MRI With Ferumoxytol Enhancement to Evaluate Cardiac Function in Congenital Heart Disease","volume":"31","author":"Si\u2010Mohamed S. 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