{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T05:03:04Z","timestamp":1789534984829,"version":"build-2803163510"},"reference-count":46,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:00:00Z","timestamp":1782172800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:00:00Z","timestamp":1782172800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["CRC 1002"],"award-info":[{"award-number":["CRC 1002"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019147","name":"Universit\u00e4tsmedizin G\u00f6ttingen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019147","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2026,10]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n Epicardial adipose tissue volume (EATV) is increasingly recognized as a cardiometabolic risk marker associated with adverse outcomes. The most established approach for EATV quantification is cardiac computed tomography (CT). MRI offers a radiation\u2010free alternative allowing simultaneous assessment of myocardial function and tissue characteristics; however, standardization and validation are limited.<\/jats:p>\n <\/jats:sec>\n \n Purpose<\/jats:title>\n To evaluate a standardized MRI\u2010based method for EATV quantification and determine its agreement with CT.<\/jats:p>\n <\/jats:sec>\n \n Study Type<\/jats:title>\n Retrospective.<\/jats:p>\n <\/jats:sec>\n \n Population<\/jats:title>\n 127 patients with aortic stenosis (AS) (78\u2009\u00b1\u20096\u2009years; 38% female) who underwent paired CT and MRI and 11 volunteers (74\u2009\u00b1\u20097\u2009years, 45% female) who underwent repeat MRI after \u2265\u20096\u2009weeks.<\/jats:p>\n <\/jats:sec>\n \n Field Strength\/Sequence<\/jats:title>\n Short\u2010axis balanced steady\u2010state free precession cine sequence at 3T (AS patients) and 1.5T (volunteers).<\/jats:p>\n <\/jats:sec>\n \n Assessment<\/jats:title>\n On CT, EATV was quantified by manual delineation of the visceral pericardium and voxel\u2010thresholding (\u2212190 to \u221230\u2009HU). MRI\u2010based EATV quantification used manual volumetry with delineation of the visceral pericardium and epicardium on end\u2010diastolic short\u2010axis cine stacks.<\/jats:p>\n <\/jats:sec>\n \n Statistical Tests<\/jats:title>\n \n Inter\u2010modality agreement was assessed by Spearman correlation and Bland\u2013Altman analysis. Reproducibility was evaluated in 20 patients using intraclass correlation coefficient (ICC) and coefficient of variation (CoV). Scan\u2010rescan reproducibility for MRI\u2010derived EATV quantification was assessed using ICC and linear regression.\n p<\/jats:italic>\n \u2009<\u20090.05 was considered significant.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Median EATV was significantly higher on MRI than CT (47 vs. 38\u2009mL\/m\n 2<\/jats:sup>\n ), with a significant moderate correlation (\n \u03c1<\/jats:italic>\n \u2009=\u20090.627) between measures. Inter\u2010 and intra\u2010observer analyses showed excellent reproducibility for both modalities (CT: intra\u2010observer ICC: 0.983, inter\u2010observer ICC: 0.994; MRI: intra\u2010observer ICC: 0.955, inter\u2010observer ICC: 0.970). MRI\u2010derived EATV quantification also showed excellent scan\u2010rescan reproducibility (ICC: 0.985).\n <\/jats:p>\n <\/jats:sec>\n \n Data Conclusion<\/jats:title>\n The standardized MRI\u2010based approach enabled highly reproducible EATV measurements with excellent repeatability. Agreement with CT was moderate, with systematically higher values on MRI, limiting direct comparability.<\/jats:p>\n <\/jats:sec>\n \n Evidence Level<\/jats:title>\n 3.<\/jats:p>\n <\/jats:sec>\n \n Stage of Technical Efficacy<\/jats:title>\n 2.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/jmri.70412","type":"journal-article","created":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T09:40:14Z","timestamp":1782207614000},"page":"1052-1063","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Standardized\n MRI<\/scp>\n \u2010Based Quantification of Epicardial Adipose Tissue Volume: Reproducibility and Agreement With Cardiac Computed Tomography"],"prefix":"10.1002","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-4953-1409","authenticated-orcid":false,"given":"Judith","family":"Gronwald","sequence":"first","affiliation":[{"name":"Department of Cardiology and Pneumology University Medical Center G\u00f6ttingen, Georg\u2010August University and German Center for Cardiovascular Research (DZHK), Partner Site Lower\u2010Saxony G\u00f6ttingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svante S.","family":"Gersch","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Pneumology University Medical Center G\u00f6ttingen, Georg\u2010August University and German Center for Cardiovascular Research (DZHK), Partner Site Lower\u2010Saxony G\u00f6ttingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zo\u00e9","family":"B\u00f6ttiger","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Pneumology University Medical Center G\u00f6ttingen, Georg\u2010August University and German Center for Cardiovascular Research (DZHK), Partner Site Lower\u2010Saxony G\u00f6ttingen 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