{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T04:03:49Z","timestamp":1790395429905,"version":"4.1.0"},"reference-count":47,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T00:00:00Z","timestamp":1789603200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T00:00:00Z","timestamp":1789603200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance Imaging"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Non\u2010motor symptoms may precede motor diagnosis in Parkinson's disease (PD), but whether distinct prodromal phenotypes exhibit differential limbic structural alterations remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To investigate limbic structural alterations across prodromal PD phenotypes defined by rapid eye movement sleep behavior disorder (RBD) and\/or hyposmia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Type<\/jats:title>\n                    <jats:p>Retrospective cross\u2010sectional study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Population\/Subjects<\/jats:title>\n                    <jats:p>\n                      315 age\u2010 and sex\u2010matched participants (mean age\u2009=\u200968.34\u2009years; 233 men and 82 women): healthy controls (HC), prodromal RBD without hyposmia, hyposmia without RBD\/dream\u2010enactment behavior, hyposmia with RBD\/dream\u2010enactment behavior, and untreated PD (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200963\/group).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Field Strength\/Sequence<\/jats:title>\n                    <jats:p>3T sagittal T1\u2010weighted 3D MPRAGE or equivalent sequences; nominal slice thickness\u2009=\u20091.0\u2009mm; in\u2010plane resolution\u2009=\u20091.0\u2009\u00d7\u20091.0\u2009mm; matrix\u2009=\u2009256\u2009\u00d7\u2009256; FOV\u2009=\u2009256\u2009mm.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Assessment<\/jats:title>\n                    <jats:p>Volumes of 34 limbic regions were extracted using FreeSurfer and ScLimbic, normalized to estimated total intracranial volume, and harmonized with ComBat.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Statistical Tests<\/jats:title>\n                    <jats:p>\n                      One\u2010way ANCOVA, post hoc comparisons, trend analyses, rank\u2010based partial correlations, and structural covariance analyses. False discovery rate (FDR)\u2010adjusted\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05 was considered significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      After FDR correction, significant group differences were mainly observed in the insula (left: 5.20\u2009\u00b1\u20091.74, 4.64\u2009\u00b1\u20091.77, 4.48\u2009\u00b1\u20091.50, 4.03\u2009\u00b1\u20091.30, 3.92\u2009\u00b1\u20092.14; right: 5.26\u2009\u00b1\u20091.74, 4.56\u2009\u00b1\u20092.00, 4.30\u2009\u00b1\u20091.47, 3.95\u2009\u00b1\u20091.43, 3.89\u2009\u00b1\u20092.36), orbitofrontal cortex (left: 9.46\u2009\u00b1\u20092.82, 8.48\u2009\u00b1\u20093.42, 7.63\u2009\u00b1\u20093.17, 7.38\u2009\u00b1\u20093.03, 6.63\u2009\u00b1\u20093.79; right: 9.37\u2009\u00b1\u20092.89, 8.51\u2009\u00b1\u20093.33, 7.85\u2009\u00b1\u20093.05, 7.16\u2009\u00b1\u20092.74, 6.97\u2009\u00b1\u20093.89), and left parahippocampal gyrus (1.56\u2009\u00b1\u20090.77, 1.56\u2009\u00b1\u20090.72, 1.29\u2009\u00b1\u20090.70, 1.10\u2009\u00b1\u20090.59, 0.97\u2009\u00b1\u20091.03). Across exploratory phenotype orderings, the strongest negative linear trends were observed in the orbitofrontal cortex (left:\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u2009\u22120.319 and \u22120.287; right:\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u2009\u22120.297 and \u22120.266), and left parahippocampal gyrus (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u2009\u22120.297 and \u22120.268). Within\u2010group covariance maps revealed phenotype\u2010specific significant covariance patterns involving olfactory\u2010related and Papez circuit regions after FDR correction.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Conclusion<\/jats:title>\n                    <jats:p>Limbic structural alterations differed across prodromal phenotypes. Hyposmia\u2010related phenotypes showed more extensive involvement of olfactory\u2010related and Papez circuit brain regions than RBD, while structural covariance patterns suggest phenotype\u2010specific differences in limbic structures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Evidence Level<\/jats:title>\n                    <jats:p>3.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Technical Efficacy<\/jats:title>\n                    <jats:p>Stage 2.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jmri.70544","type":"journal-article","created":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T03:01:52Z","timestamp":1789700512000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Limbic Structural Alterations and Structural Covariance Across Prodromal Phenotypes and Early Parkinson's Disease"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2205-8789","authenticated-orcid":false,"given":"Yuanyuan","family":"Zhao","sequence":"first","affiliation":[{"name":"The Fourth Clinical Medical College, Zhejiang Chinese Medical University  Hangzhou China"},{"name":"Department of Radiology, Affiliated Hangzhou First People's Hospital Westlake University School of Medicine  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7780-7190","authenticated-orcid":false,"given":"Luoyu","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Affiliated Hangzhou First People's Hospital Westlake University School of Medicine  Hangzhou China"},{"name":"School of Biomedical Engineering ShanghaiTech University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yihan","family":"Suo","sequence":"additional","affiliation":[{"name":"The Fourth Clinical Medical College, Zhejiang Chinese Medical University  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-1467-5519","authenticated-orcid":false,"given":"Maoling","family":"Liu","sequence":"additional","affiliation":[{"name":"Hangzhou Medical College  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-7353-6259","authenticated-orcid":false,"given":"Yi","family":"Lin","sequence":"additional","affiliation":[{"name":"The Fourth Clinical Medical College, Zhejiang Chinese Medical University  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lidan","family":"Fang","sequence":"additional","affiliation":[{"name":"The Fourth Clinical Medical College, Zhejiang Chinese Medical University  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7691-5571","authenticated-orcid":false,"given":"Zhongxiang","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Radiology, Affiliated Hangzhou First People's Hospital Westlake University School of Medicine  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,17]]},"reference":[{"issue":"7","key":"e_1_2_9_2_1","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1038\/nrn.2017.62","article-title":"Non\u2010Motor Features of Parkinson Disease","volume":"18","author":"Schapira A. H. V.","year":"2017","journal-title":"Nature Reviews. Neuroscience"},{"issue":"6","key":"e_1_2_9_3_1","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1007\/s00702-023-02635-4","article-title":"The Heterogeneity of Parkinson's Disease","volume":"130","author":"W\u00fcllner U.","year":"2023","journal-title":"Journal of Neural Transmission (Vienna)"},{"key":"e_1_2_9_4_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.parkreldis.2024.106078","article-title":"Towards a Biological Diagnosis of PD","volume":"122","author":"Chopra A.","year":"2024","journal-title":"Parkinsonism & Related Disorders"},{"issue":"6","key":"e_1_2_9_5_1","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/s41582-021-00486-9","article-title":"Prodromal Parkinson Disease Subtypes \u2010 Key to Understanding Heterogeneity","volume":"17","author":"Berg D.","year":"2021","journal-title":"Nature Reviews. Neurology"},{"issue":"12","key":"e_1_2_9_6_1","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1002\/mds.26431","article-title":"MDS Research Criteria for Prodromal Parkinson's Disease","volume":"30","author":"Berg D.","year":"2015","journal-title":"Movement Disorders"},{"issue":"10","key":"e_1_2_9_7_1","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1002\/mds.27802","article-title":"Update of the MDS Research Criteria for Prodromal Parkinson's Disease","volume":"34","author":"Heinzel S.","year":"2019","journal-title":"Movement Disorders"},{"issue":"7","key":"e_1_2_9_8_1","doi-asserted-by":"crossref","first-page":"3566","DOI":"10.1002\/hbm.23610","article-title":"Limbic Grey Matter Changes in Early Parkinson's Disease","volume":"38","author":"Li X.","year":"2017","journal-title":"Human Brain Mapping"},{"issue":"9","key":"e_1_2_9_9_1","doi-asserted-by":"crossref","DOI":"10.3390\/brainsci12091248","article-title":"Imaging the Limbic System in Parkinson's Disease\u2010A Review of Limbic Pathology and Clinical Symptoms","volume":"12","author":"Banwinkler M.","year":"2022","journal-title":"Brain Sciences"},{"key":"e_1_2_9_10_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.neubiorev.2022.104813","article-title":"Time to Retire the Serial Papez Circuit: Implications for Space, Memory, and Attention","volume":"140","author":"Aggleton J. P.","year":"2022","journal-title":"Neuroscience and Biobehavioral Reviews"},{"issue":"9","key":"e_1_2_9_11_1","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1038\/nrn.2017.74","article-title":"Prefrontal\u2010Hippocampal Interactions in Episodic Memory","volume":"18","author":"Eichenbaum H.","year":"2017","journal-title":"Nature Reviews. Neuroscience"},{"key":"e_1_2_9_12_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.parkreldis.2024.107230","article-title":"Structural and Functional Connectomics of the Olfactory System in Parkinson's Disease: A Systematic Review","volume":"132","author":"Ielo A.","year":"2025","journal-title":"Parkinsonism & Related Disorders"},{"issue":"10","key":"e_1_2_9_13_1","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1001\/jamaoto.2021.2026","article-title":"Evaluation of the Neuroanatomical Basis of Olfactory Dysfunction in the General Population","volume":"147","author":"Lu R.","year":"2021","journal-title":"JAMA Otolaryngology. Head & Neck Surgery"},{"issue":"8","key":"e_1_2_9_14_1","doi-asserted-by":"crossref","DOI":"10.3390\/brainsci12080963","article-title":"Association Between Functional Connectivity of Entorhinal Cortex and Olfactory Performance in Parkinson's Disease","volume":"12","author":"Fan W.","year":"2022","journal-title":"Brain Sciences"},{"key":"e_1_2_9_15_1","doi-asserted-by":"crossref","DOI":"10.3389\/fnagi.2022.1071520","article-title":"Olfactory Functional Covariance Connectivity in Parkinson's Disease: Evidence From a Chinese Population","volume":"14","author":"Du S.","year":"2022","journal-title":"Frontiers in Aging Neuroscience"},{"issue":"3","key":"e_1_2_9_16_1","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1136\/jnnp-2020-325361","article-title":"Olfactory Impairment as an Early Marker of Parkinson's Disease in REM Sleep Behaviour Disorder: A Systematic Review and Meta\u2010Analysis","volume":"92","author":"Lyu Z.","year":"2021","journal-title":"Journal of Neurology, Neurosurgery, and Psychiatry"},{"issue":"3","key":"e_1_2_9_17_1","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1093\/brain\/awz030","article-title":"Risk and Predictors of Dementia and Parkinsonism in Idiopathic REM Sleep Behaviour Disorder: A Multicentre Study","volume":"142","author":"Postuma R. B.","year":"2019","journal-title":"Brain"},{"issue":"10","key":"e_1_2_9_18_1","doi-asserted-by":"crossref","first-page":"1815","DOI":"10.1002\/jnr.25099","article-title":"Neuroimaging of Rapid Eye Movement Sleep Behavior Disorder and Its Relation to Parkinson's Disease","volume":"100","author":"Valli M.","year":"2022","journal-title":"Journal of Neuroscience Research"},{"issue":"1","key":"e_1_2_9_19_1","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1002\/mds.29662","article-title":"Charting Disease Trajectories From Isolated REM Sleep Behavior Disorder to Parkinson's Disease","volume":"39","author":"Di Folco C.","year":"2024","journal-title":"Movement Disorders"},{"issue":"1","key":"e_1_2_9_20_1","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1038\/s41531-022-00326-7","article-title":"Brain Atrophy Pattern in De Novo Parkinson's Disease With Probable RBD Associated With Cognitive Impairment","volume":"8","author":"Oltra J.","year":"2022","journal-title":"NPJ Parkinsons Disease"},{"key":"e_1_2_9_21_1","doi-asserted-by":"crossref","first-page":"334","DOI":"10.3389\/fneur.2018.00334","article-title":"Alterations of Brain Structural Network in Parkinson's Disease With and Without Rapid Eye Movement Sleep Behavior Disorder","volume":"9","author":"Guo T.","year":"2018","journal-title":"Frontiers in Neurology"},{"key":"e_1_2_9_22_1","doi-asserted-by":"crossref","DOI":"10.3389\/fncir.2024.1503841","article-title":"Specific Structural Changes in Parkinson's Disease\u2010Related Olfactory Dysfunction Compared to Others Forms of Olfactory Dysfunction","volume":"18","author":"Brosse S.","year":"2024","journal-title":"Frontiers in Neural Circuits"},{"issue":"5","key":"e_1_2_9_23_1","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1007\/s12264-017-0170-x","article-title":"Olfactory Dysfunction as an Early Biomarker in Parkinson's Disease","volume":"33","author":"Fullard M. E.","year":"2017","journal-title":"Neuroscience Bulletin"},{"key":"e_1_2_9_24_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.parkreldis.2025.107964","article-title":"Olfactory Network Reorganization in Parkinson's Disease","volume":"138","author":"Saqib M.","year":"2025","journal-title":"Parkinsonism & Related Disorders"},{"issue":"4","key":"e_1_2_9_25_1","doi-asserted-by":"crossref","DOI":"10.3390\/diagnostics15040470","article-title":"Brain Morphometry and Cognitive Features in the Prediction of Irritable Bowel Syndrome","volume":"15","author":"Lundervold A.","year":"2025","journal-title":"Diagnostics (Basel)"},{"key":"e_1_2_9_26_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2021.118610","article-title":"A Deep Learning Toolbox for Automatic Segmentation of Subcortical Limbic Structures From MRI Images","volume":"244","author":"Greve D. N.","year":"2021","journal-title":"NeuroImage"},{"key":"e_1_2_9_27_1","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.neuroimage.2015.04.042","article-title":"A Computational Atlas of the Hippocampal Formation Using Ex\u00a0Vivo, Ultra\u2010High Resolution MRI: Application to Adaptive Segmentation of In\u00a0Vivo MRI","volume":"115","author":"Iglesias J. E.","year":"2015","journal-title":"NeuroImage"},{"key":"e_1_2_9_28_1","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.neuroimage.2018.08.012","article-title":"A Probabilistic Atlas of the Human Thalamic Nuclei Combining Ex\u00a0Vivo MRI and Histology","volume":"183","author":"Iglesias J. E.","year":"2018","journal-title":"NeuroImage"},{"issue":"2","key":"e_1_2_9_29_1","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/j.neuroimage.2004.06.018","article-title":"A Unified Approach for Morphometric and Functional Data Analysis in Young, Old, and Demented Adults Using Automated Atlas\u2010Based Head Size Normalization: Reliability and Validation Against Manual Measurement of Total Intracranial Volume","volume":"23","author":"Buckner R. L.","year":"2004","journal-title":"NeuroImage"},{"key":"e_1_2_9_30_1","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.neuroimage.2017.11.024","article-title":"Harmonization of Cortical Thickness Measurements Across Scanners and Sites","volume":"167","author":"Fortin J. P.","year":"2018","journal-title":"NeuroImage"},{"issue":"2","key":"e_1_2_9_31_1","doi-asserted-by":"crossref","first-page":"172","DOI":"10.2967\/jnumed.121.262464","article-title":"A Guide to ComBat Harmonization of Imaging Biomarkers in Multicenter Studies","volume":"63","author":"Orlhac F.","year":"2022","journal-title":"Journal of Nuclear Medicine"},{"issue":"27","key":"e_1_2_9_32_1","doi-asserted-by":"crossref","first-page":"4316","DOI":"10.1002\/sim.7433","article-title":"Modeling Continuous Response Variables Using Ordinal Regression","volume":"36","author":"Liu Q.","year":"2017","journal-title":"Statistics in Medicine"},{"key":"e_1_2_9_33_1","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1080\/00031305.1981.10479327","article-title":"Rank Transformations as a Bridge Between Parametric and Nonparametric Statistics","volume":"35","author":"Conover W. J.","year":"1981","journal-title":"American Statistician"},{"key":"e_1_2_9_34_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.parkreldis.2024.106101","article-title":"Brain\u2010First vs. Body\u2010First Parkinson's Disease: An Update on Recent Evidence","volume":"122","author":"Horsager J.","year":"2024","journal-title":"Parkinsonism & Related Disorders"},{"issue":"2","key":"e_1_2_9_35_1","doi-asserted-by":"crossref","first-page":"S275","DOI":"10.3233\/JPD-230348","article-title":"Opportunities and Pitfalls of REM Sleep Behavior Disorder and Olfactory Dysfunction as Early Markers in Parkinson's Disease","volume":"14","author":"Orso B.","year":"2024","journal-title":"Journal of Parkinson's Disease"},{"key":"e_1_2_9_36_1","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.sleep.2024.03.012","article-title":"The Functional Brain Connectome in Isolated Rapid Eye Movement Sleep Behavior Disorder and Parkinson's Disease","volume":"117","author":"Holtbernd F.","year":"2024","journal-title":"Sleep Medicine"},{"issue":"4","key":"e_1_2_9_37_1","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1002\/mds.28895","article-title":"Disruption of Brainstem Structural Connectivity in REM Sleep Behavior Disorder Using 7 Tesla Magnetic Resonance Imaging","volume":"37","author":"Garc\u00eda\u2010Gomar M. G.","year":"2022","journal-title":"Movement Disorders"},{"issue":"8","key":"e_1_2_9_38_1","doi-asserted-by":"crossref","first-page":"3258","DOI":"10.1093\/brain\/awad072","article-title":"Progression of Clinical Markers in Prodromal Parkinson's Disease and Dementia With Lewy Bodies: A Multicentre Study","volume":"146","author":"Joza S.","year":"2023","journal-title":"Brain"},{"issue":"4","key":"e_1_2_9_39_1","doi-asserted-by":"crossref","DOI":"10.1002\/brb3.2956","article-title":"Role of the Amygdala\u2010Medial Orbitofrontal Relationship in Odor Recognition in the Elderly","volume":"13","author":"Sakikawa K.","year":"2023","journal-title":"Brain and Behavior: A Cognitive Neuroscience Perspective"},{"issue":"1","key":"e_1_2_9_40_1","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1038\/s41531-023-00469-1","article-title":"Common and Distinct Roles of Amygdala Subregional Functional Connectivity in Non\u2010Motor Symptoms of Parkinson's Disease","volume":"9","author":"Wang J.","year":"2023","journal-title":"NPJ Parkinsons Disease"},{"key":"e_1_2_9_41_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.pneurobio.2022.102385","article-title":"Human Amygdala Compared to Orbitofrontal Cortex Connectivity, and Emotion","volume":"220","author":"Rolls E. T.","year":"2023","journal-title":"Progress in Neurobiology"},{"issue":"1","key":"e_1_2_9_42_1","doi-asserted-by":"crossref","first-page":"10957","DOI":"10.1038\/s41598-020-67770-4","article-title":"The Anterior and Medial Thalamic Nuclei and the Human Limbic System: Tracing the Structural Connectivity Using Diffusion\u2010Weighted Imaging","volume":"10","author":"Grodd W.","year":"2020","journal-title":"Scientific Reports"},{"issue":"3","key":"e_1_2_9_43_1","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/s10548-023-00955-y","article-title":"The Cortico\u2010Limbo\u2010Thalamo\u2010Cortical Circuits: An Update to the Original Papez Circuit of the Human Limbic System","volume":"36","author":"Kamali A.","year":"2023","journal-title":"Brain Topography"},{"issue":"12","key":"e_1_2_9_44_1","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1016\/j.tins.2021.10.003","article-title":"The Many Dimensions of Human Hippocampal Organization and (Dys)function","volume":"44","author":"Genon S.","year":"2021","journal-title":"Trends in Neurosciences"},{"issue":"11","key":"e_1_2_9_45_1","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1016\/j.tins.2023.08.003","article-title":"The Role of the Hippocampus in the Consolidation of Emotional Memories During Sleep","volume":"46","author":"Pronier \u00c9.","year":"2023","journal-title":"Trends in Neurosciences"},{"key":"e_1_2_9_46_1","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.neuroimage.2013.05.054","article-title":"Networks of Anatomical Covariance","volume":"80","author":"Evans A. C.","year":"2013","journal-title":"NeuroImage"},{"issue":"9","key":"e_1_2_9_47_1","doi-asserted-by":"crossref","first-page":"3072","DOI":"10.1093\/brain\/awaf151","article-title":"Structural Covariance Analysis for Neurodegenerative and Neuroinflammatory Brain Disorders","volume":"148","author":"Mongay\u2010Ochoa N.","year":"2025","journal-title":"Brain"},{"key":"e_1_2_9_48_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2020.117104","article-title":"Reliability and Comparability of Human Brain Structural Covariance Networks","volume":"220","author":"Carmon J.","year":"2020","journal-title":"NeuroImage"}],"container-title":["Journal of Magnetic Resonance Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmri.70544","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jmri.70544","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmri.70544","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T03:02:06Z","timestamp":1789700526000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmri.70544"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,17]]},"references-count":47,"alternative-id":["10.1002\/jmri.70544"],"URL":"https:\/\/doi.org\/10.1002\/jmri.70544","archive":["Portico"],"relation":{},"ISSN":["1053-1807","1522-2586"],"issn-type":[{"value":"1053-1807","type":"print"},{"value":"1522-2586","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,17]]},"assertion":[{"value":"2026-05-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"jmri.70544"}}