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Radiotherapy is the mainstay treatment for <jats:styled-content style=\"fixed-case\">NPC<\/jats:styled-content> due to its relatively high radiosensitivity and deep\u2010seated anatomical position, which is not readily accessible by surgery. Although the technique of radiotherapy in <jats:styled-content style=\"fixed-case\">NPC<\/jats:styled-content> has been advancing and offers promising treatment outcome, complications around the irradiation areas are inevitable and the quality of life of the post\u2010radiotherapy patients is often compromised. Trismus, which is defined as the restricted mouth opening or jaw movement due to the disorder of temporo\u2010mandibular joint (<jats:styled-content style=\"fixed-case\">TMJ<\/jats:styled-content>), is one of the possible late complications for radiotherapy of <jats:styled-content style=\"fixed-case\">NPC<\/jats:styled-content> and is found in 5\u201317% of the post\u2010radiotherapy (post\u2010<jats:styled-content style=\"fixed-case\">RT<\/jats:styled-content>) patients. Trismus at early stage may only affect the speech, but in severe cases nutritional intake and oral hygiene condition may deteriorate seriously. This article reviewed the possible causes of radiation\u2010induced <jats:styled-content style=\"fixed-case\">TMJ<\/jats:styled-content> damage, the various assessments including imaging modalities and possible treatments. The conclusion is that the availability of simple, yet effective examinations for trismus is essential for delaying the progression and restoring <jats:styled-content style=\"fixed-case\">TMJ<\/jats:styled-content> functions. Although there is no absolutely effective treatment for trismus, many supportive, restorative and palliative management are possible under different clinical situations.<\/jats:p>","DOI":"10.1002\/jmrs.145","type":"journal-article","created":{"date-parts":[[2015,11,20]],"date-time":"2015-11-20T06:04:38Z","timestamp":1447999478000},"page":"124-132","source":"Crossref","is-referenced-by-count":26,"title":["Radiation\u2010induced temporo\u2010mandibular joint disorder in post\u2010radiotherapy nasopharyngeal carcinoma patients: assessment and treatment"],"prefix":"10.1002","volume":"63","author":[{"given":"Vincent W. 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