{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,9]],"date-time":"2024-08-09T17:52:34Z","timestamp":1723225954309},"reference-count":9,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,3,19]],"date-time":"2016-03-19T00:00:00Z","timestamp":1458345600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Medical Radiation Sci"],"published-print":{"date-parts":[[2016,9]]},"abstract":"Abstract<\/jats:title>Introduction<\/jats:title>New surgical methods have enabled resection of previously in\u2010operable tumours in the region of the parotid gland and ear. This has translated to deeper target volumes being treated with adjuvant radiotherapy. Due to the limitations of existing conformal techniques, alternative planning approaches are required to cover the target volume with appropriate sparing of adjacent critical structures. Although intensity modulated radiation therapy (IMRT<\/jats:styled-content>) may be able to achieve these goals compared with the existing conformal method, a new orbital sparing radiation therapy (OSR<\/jats:styled-content>aT) technique was evaluated as an alternative conformal planning process. The study objective was to evaluate the dosimetry of three planning methods: pre\u2010existing conformal, IMRT<\/jats:styled-content> and OSR<\/jats:styled-content>aT techniques.<\/jats:p><\/jats:sec>Methods<\/jats:title>Ten patients were planned retrospectively using the existing three\u2010dimensional conformal radiotherapy (3DCRT<\/jats:styled-content>), IMRT<\/jats:styled-content> and OSR<\/jats:styled-content>aT techniques. Dosimetry was analysed using the homogeneity index (HI<\/jats:styled-content>), conformity index (CI<\/jats:styled-content>), the volume of planning target volumes (PTV<\/jats:styled-content>) under and over treated by the 95% isodose and dose to critical structures.<\/jats:p><\/jats:sec>Results<\/jats:title>OSR<\/jats:styled-content>aT achieved superior 95% coverage of the high\u2010dose PTV<\/jats:styled-content> while delivering HI<\/jats:styled-content> similar to IMRT<\/jats:styled-content> for intermediate and high\u2010dose PTV<\/jats:styled-content>s. The CI<\/jats:styled-content> for the high\u2010dose PTV<\/jats:styled-content> was comparable between the three techniques, however IMRT<\/jats:styled-content> was statistically better for the low\u2010 and intermediate dose PTV<\/jats:styled-content>s. All three techniques showed adequate orbital sparing, however OSR<\/jats:styled-content>aT and IMRT<\/jats:styled-content> achieved this with less under dosing of the PTV<\/jats:styled-content>s.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>For the treatment of patients with advanced skin cancer of the parotid and ear, both IMRT<\/jats:styled-content> and the OSR<\/jats:styled-content>aT techniques are viable options.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmrs.161","type":"journal-article","created":{"date-parts":[[2016,3,19]],"date-time":"2016-03-19T12:08:44Z","timestamp":1458389324000},"page":"186-194","source":"Crossref","is-referenced-by-count":1,"title":["Conformal orbit sparing radiation therapy: a treatment option for advanced skin cancer of the parotid and ear region"],"prefix":"10.1002","volume":"63","author":[{"given":"Heath","family":"Foley","sequence":"first","affiliation":[{"name":"Princess Alexandra Hospital Radiation Oncology Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shane","family":"Hopley","sequence":"additional","affiliation":[{"name":"Princess Alexandra Hospital Radiation Oncology Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Brown","sequence":"additional","affiliation":[{"name":"Princess Alexandra Hospital Radiation Oncology Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Bernard","sequence":"additional","affiliation":[{"name":"QFAB Bioinformatics Institute for Molecular Bioscience University of Queensland Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Foote","sequence":"additional","affiliation":[{"name":"Princess Alexandra Hospital Radiation Oncology Brisbane Queensland Australia"},{"name":"School of Medicine University of Queensland Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,3,19]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20576"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016480802642096"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24063"},{"key":"e_1_2_8_5_1","first-page":"34","article-title":"ICRU report 83: Prescribing, recording, and reporting photon\u2010beam intensity\u2010modulated radiation therapy (IMRT)","volume":"10","author":"ICRU","year":"2010","journal-title":"J ICRU"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2009.02.091"},{"key":"e_1_2_8_7_1","volume-title":"The Physics of Radiation Therapy","author":"Khan M","year":"2003"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clon.2010.06.013"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1507-1367(10)60101-0"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prro.2013.04.002"}],"container-title":["Journal of Medical Radiation Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmrs.161","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmrs.161","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jmrs.161","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmrs.161","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T11:25:43Z","timestamp":1696245943000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmrs.161"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,19]]},"references-count":9,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["10.1002\/jmrs.161"],"URL":"https:\/\/doi.org\/10.1002\/jmrs.161","archive":["Portico"],"relation":{},"ISSN":["2051-3895","2051-3909"],"issn-type":[{"value":"2051-3895","type":"print"},{"value":"2051-3909","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,19]]}}}