{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:24:59Z","timestamp":1747149899052,"version":"3.40.5"},"reference-count":12,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,4,3]],"date-time":"2019-04-03T00:00:00Z","timestamp":1554249600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Medical Radiation Sci"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The aim of this study was to evaluate the suitability of using cone\u2010beam computed tomography (<jats:styled-content style=\"fixed-case\">CBCT<\/jats:styled-content>) obtained with a mobile C\u2010arm X\u2010ray fluoroscopy unit as a single modality for planning of high\u2010dose\u2010rate (<jats:styled-content style=\"fixed-case\">HDR<\/jats:styled-content>) prostate brachytherapy treatments.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The feasibility of using <jats:styled-content style=\"fixed-case\">CBCT<\/jats:styled-content> images obtained using a Siemens Arcadis Orbic 3D mobile C\u2010arm was evaluated. A retrospective clinical study was undertaken of six participants undergoing <jats:styled-content style=\"fixed-case\">HDR<\/jats:styled-content> prostate brachytherapy. Plans generated using images from a Toshiba Aquilion One <jats:styled-content style=\"fixed-case\">LB CT<\/jats:styled-content> were compared with those generated using <jats:styled-content style=\"fixed-case\">CBCT<\/jats:styled-content> images. After rigid spatial registration, the plans were compared based on various parameters such as dose\u2010volume histograms, overlap quantities and metrics, and dose constraints.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Provided they were within the limited field of view, the brachytherapy catheters and fiducial markers were clearly visible in the <jats:styled-content style=\"fixed-case\">CBCT<\/jats:styled-content> images and thus, localisable and identifiable in the treatment planning process. The Siemens <jats:styled-content style=\"fixed-case\">CBCT<\/jats:styled-content> underestimated <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> numbers leading to poorer tissue contrast which exacerbated the difficulties in delineation of the target tumour and the surrounding organs at risk. Between <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>\u2010 and <jats:styled-content style=\"fixed-case\">CBCT<\/jats:styled-content>\u2010based plans, the mean difference of <jats:styled-content style=\"fixed-case\">CTV<\/jats:styled-content>\u2010<jats:italic>D<\/jats:italic><jats:sub>90<\/jats:sub> was 1.58\u00a0Gy, <jats:styled-content style=\"fixed-case\">CTV<\/jats:styled-content>\u2010<jats:italic>V<\/jats:italic><jats:sub>100<\/jats:sub> was 12.13%, rectum\u2010<jats:italic>V<\/jats:italic><jats:sub>80<\/jats:sub> was 0.06% and urethra\u2010<jats:italic>V<\/jats:italic><jats:sub>120<\/jats:sub> was \u22120.70%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>It was not feasible to solely utilise the Siemens Arcadis Orbic 3D for <jats:styled-content style=\"fixed-case\">HDR<\/jats:styled-content> prostate brachytherapy treatment planning due to suboptimal organ delineation. However, the methods in this study could be used to evaluate other mobile <jats:styled-content style=\"fixed-case\">CBCT<\/jats:styled-content> imaging devices for feasibility in <jats:styled-content style=\"fixed-case\">HDR<\/jats:styled-content> brachytherapy treatment planning since the results indicated that it may not be necessary to have standard quality <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> images for treatment planning.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmrs.331","type":"journal-article","created":{"date-parts":[[2019,4,4]],"date-time":"2019-04-04T05:24:12Z","timestamp":1554355452000},"page":"112-121","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Evaluation of a mobile C\u2010arm cone\u2010beam <scp>CT<\/scp> in interstitial high\u2010dose\u2010rate prostate brachytherapy treatment planning"],"prefix":"10.1002","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2221-5566","authenticated-orcid":false,"given":"Mario","family":"Djukelic","sequence":"first","affiliation":[{"name":"Department of Medical Technology and Physics Sir Charles Gairdner Hospital Nedlands WA Australia"},{"name":"Department of Physics The University of Western Australia Crawley WA Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Waterhouse","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Sir Charles Gairdner Hospital Nedlands WA Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan","family":"Toh","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Sir Charles Gairdner Hospital Nedlands WA Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hendrick","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of 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