{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T14:28:22Z","timestamp":1763389702196,"version":"3.40.5"},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,2,21]],"date-time":"2023-02-21T00:00:00Z","timestamp":1676937600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Medical Radiation Sci"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Despite the development of DOSIRIS\u2122, an eye lens dosimeter, the characteristics of DOSIRIS\u2122 in the area of radiotherapy have not been investigated. The purpose of this study was to evaluate the basic characteristics of the 3\u2010mm dose equivalent measuring instrument DOSIRIS\u2122 in radiotherapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Dose linearity and energy dependence were evaluated for the irradiation system based on the calibration method of the monitor dosimeter. The angle dependence was measured by irradiating from a total of 18 directions. Interdevice variation was repeated three times by simultaneously irradiating five dosimeters. The measurement accuracy was based on the absorbed dose measured by the monitor dosimeter of the radiotherapy equipment. Absorbed doses were converted to 3\u2010mm dose equivalents and compared with DOSIRIS\u2122 measurements.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Dose linearity was evaluated using the determination coefficient (<jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>) <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a00.9998 and 0.9996 at 6 and 10 MV, respectively. For energy dependence, although the therapeutic photons evaluated in this study had higher energies than in the previous studies and had a continuous spectrum, the response was equivalent to 0.2\u20131.25\u2009MeV, well below the IEC 62387 limits. The maximum error at all angles was 15% (angle of 140\u00b0) and the coefficient of variation at all angles was 4.70%, which satisfies the standard of the thermoluminescent dosimeter measuring instrument. Accuracy of measurement was determined in terms of the measurement errors for DOSIRIS\u2122 (3.2% and 4.3% at 6 and 10 MV, respectively,) using the 3\u2010mm dose equivalent obtained from the theoretical value as a reference. The DOSIRIS\u2122 measurements met the IEC standard which defines the measurement error of \u00b130% of the irradiance value in IEC 62387.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We found that the characteristics of the 3\u2010mm dose equivalent dosimeter in a high\u2010energy radiation satisfy the IEC standards and have the same measurement accuracy as diagnostic areas such as Interventional Radiology.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmrs.653","type":"journal-article","created":{"date-parts":[[2023,2,22]],"date-time":"2023-02-22T04:44:16Z","timestamp":1677041056000},"page":"154-160","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of basic characteristics of 3\u2010mm dose equivalent measuring instrument for evaluating lens exposure dose in radiotherapy"],"prefix":"10.1002","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6487-0940","authenticated-orcid":false,"given":"Yutaro","family":"Mori","sequence":"first","affiliation":[{"name":"Faculty of Medicine University of Tsukuba  Tsukuba Japan"},{"name":"Proton Medical Research Center University of Tsukuba Hospital  Tsukuba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomonori","family":"Isobe","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Tsukuba  Tsukuba Japan"},{"name":"Proton Medical Research Center University of Tsukuba Hospital  Tsukuba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideyuki","family":"Takei","sequence":"additional","affiliation":[{"name":"Quantum Life and Medical Science Directorate National Institute for Quantum Science and Technology  Inage\u2010ku Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shohei","family":"Miyazaki","sequence":"additional","affiliation":[{"name":"Department of Radiology University of Tsukuba Hospital  Tsukuba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Kamizawa","sequence":"additional","affiliation":[{"name":"Proton Medical Research Center University of Tsukuba Hospital  Tsukuba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuya","family":"Tomita","sequence":"additional","affiliation":[{"name":"Department of Radiology University of Tsukuba Hospital  Tsukuba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisuke","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Department of Radiology University of Tsukuba Hospital  Tsukuba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideyuki","family":"Sakurai","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Tsukuba  Tsukuba Japan"},{"name":"Proton Medical Research Center University of Tsukuba Hospital  Tsukuba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeji","family":"Sakae","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Tsukuba  Tsukuba Japan"},{"name":"Proton Medical Research Center University of Tsukuba Hospital  Tsukuba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,2,21]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"International Commission on Radiological Protection.Statement on tissue reactions [online].2011. Available at:http:\/\/www.icrp.org\/docs\/ICRP%20Statement%20on%20Tissue%20Reactions.pdf. (Last accessed on 2022 May 9)."},{"issue":"1","key":"e_1_2_8_3_1","first-page":"1","article-title":"ICRP statement on tissue reactions\/early and late effects of radiation in normal tissues and organs \u2010 threshold doses for tissue reactions in a radiation protection context. ICRP publication 118","volume":"41","author":"International Commission on Radiological Protection","year":"2012","journal-title":"Ann ICRP"},{"issue":"1","key":"e_1_2_8_4_1","first-page":"1","article-title":"1990 recommendations of the international commission on radiological protection. 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Available at:http:\/\/dosimetre.irsn.fr\/en\u2010us\/Documents\/Product%20files\/DOSIRIS%20EN%20WEB.pdf. 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