{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T05:48:11Z","timestamp":1777355291626,"version":"3.51.4"},"reference-count":9,"publisher":"Wiley","issue":"S2","license":[{"start":{"date-parts":[[2026,3,22]],"date-time":"2026-03-22T00:00:00Z","timestamp":1774137600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,3,22]],"date-time":"2026-03-22T00:00:00Z","timestamp":1774137600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Medical Radiation Sci"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Simulation\u2010free radiotherapy (SF\u2010RT) is a radiotherapy workflow which is growing in use in palliative treatment, allowing for planning on existing diagnostic CT (dCT) scans without the need for a dedicated planning CT (pCT). While this approach is being increasingly adopted in the adult population, its application in paediatric settings has been limited thus far.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>We describe the first published report of two paediatric patients treated with SF\u2010RT in a palliative context. Both children had advanced malignancies and were referred for single\u2010fraction radiotherapy for symptom management. In the first case, a 5\u2010year\u2010old child underwent radiotherapy under general anaesthesia (GA) using SF\u2010RT, eliminating the need for an additional GA for CT\u2010Simulation (CT\u2010Sim). In the second case, a 6\u2010year\u2010old child received treatment without GA, supported by other non\u2010anaesthetic pharmacological interventions and surface guided radiation therapy (SGRT) for accurate positioning and intrafraction monitoring.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>SF\u2010RT enabled expedited treatment in both cases while reducing procedural burden. Two GA interventions were eliminated with the use of SF\u2010RT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>SF\u2010RT shows promise in reducing GA requirements in paediatric palliative radiotherapy, offering benefits for patient experience and healthcare resource utilisation. These cases support the feasibility of SF\u2010RT in select paediatric patients and highlight the need for broader implementation and further investigation in this population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jmrs.70074","type":"journal-article","created":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T05:36:58Z","timestamp":1774244218000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Streamlining Paediatric Palliative Radiotherapy: A Case Study on Reducing Procedural Burden and Avoiding General Anaesthesia Using a Simulation\u2010Free Radiotherapy (\n                    <scp>SF<\/scp>\n                    \u2010\n                    <scp>RT<\/scp>\n                    ) Protocol"],"prefix":"10.1002","volume":"73","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-5057-7705","authenticated-orcid":false,"given":"Alice","family":"Eriksen","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology Peter MacCallum Cancer Centre  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Murphy","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Peter MacCallum Cancer Centre  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-5301-0079","authenticated-orcid":false,"given":"Jennifer","family":"Chard","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Peter MacCallum Cancer Centre  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Greg","family":"Wheeler","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Peter MacCallum Cancer Centre  Melbourne Victoria Australia"},{"name":"The Sir Peter MacCallum Department of Oncology University of Melbourne  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wai\u2010Yan","family":"Poon","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Peter MacCallum Cancer Centre  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lily","family":"Yau","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Peter MacCallum Cancer Centre  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Ungureanu","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Peter MacCallum Cancer Centre  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenton","family":"Thompson","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Peter MacCallum Cancer Centre  Melbourne Victoria Australia"},{"name":"The Sir Peter MacCallum Department of Oncology University of Melbourne  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-9411-153X","authenticated-orcid":false,"given":"Katrina","family":"Woodford","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Peter MacCallum Cancer Centre  Melbourne Victoria Australia"},{"name":"Department of Medical Imaging and Radiation Sciences Monash University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,22]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2024.03.005"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2024.09.041"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.adro.2022.101091"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.adro.2023.101361"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phro.2023.100456"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.adro.2020.100632"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radi.2013.08.004"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2017.11.080"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prro.2020.10.010"}],"container-title":["Journal of Medical Radiation 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