{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T05:48:36Z","timestamp":1777355316199,"version":"3.51.4"},"reference-count":35,"publisher":"Wiley","issue":"S2","license":[{"start":{"date-parts":[[2025,6,29]],"date-time":"2025-06-29T00:00:00Z","timestamp":1751155200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,6,29]],"date-time":"2025-06-29T00:00:00Z","timestamp":1751155200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100014467","name":"Western Sydney Local Health District","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014467","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Medical Radiation Sci"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Contouring organs at risk (OARs) manually in paediatric patients undergoing cranial\u2010spinal radiation therapy (CSI) is a time\u2010consuming, labour\u2010intensive task. This study aims to assess the accuracy and clinical acceptability of auto\u2010contours produced by the Siemens DirectORGANS auto\u2010contouring software on paediatric patients receiving CSI treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Auto\u2010contours of OARs were produced using the Siemens DirectORGANS Auto\u2010contouring Software from 20 paediatric CSI patients datasets that had previously been manually contoured by a paediatric specialist radiation therapist (RT) for plan production. Manual and auto\u2010contours were retrospectively analysed using quantitative (Dice Similarity Coefficient, Hausdorff Distance, Mean Distance to Agreement) and qualitative (Likert ratings, Turing test) assessment techniques.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Auto\u2010contoured structures were clinically acceptable for use without edits 72.8% of the time, and manual contours were clinically acceptable for use 91.7% of the time. The liver was the only auto\u2010contoured structure that performed better than the manual equivalent. Poor performance by the auto contouring tool was noted for structures surrounded by low contrast edges, such as the breasts, oesophagus, and brainstem, in both quantitative and qualitative assessment techniques. Brain auto\u2010contours were deemed not suitable for clinical use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The clinical acceptability of many of the auto\u2010contours favours the implementation of this auto\u2010contouring system for clinical use. However, prior to use, all contours should be critically assessed and edited accordingly. Our study results indicate that whilst auto\u2010contouring tools are designed for adult populations, they are suitable for use on paediatric patients when used with caution.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jmrs.893","type":"journal-article","created":{"date-parts":[[2025,7,13]],"date-time":"2025-07-13T12:32:59Z","timestamp":1752409979000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of Auto\u2010Contouring Tools for Delineation of Normal Organs at Risk in Paediatric Patients Undergoing Radiotherapy"],"prefix":"10.1002","volume":"73","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-8818-2917","authenticated-orcid":false,"given":"Isabel","family":"Cant","sequence":"first","affiliation":[{"name":"Crown Princess Mary Cancer Centre Westmead Hospital  Westmead New South Wales Australia"},{"name":"Blacktown Cancer and Haematology Centre Blacktown Hospital  Blacktown New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3823-3892","authenticated-orcid":false,"given":"Jonathan","family":"Sykes","sequence":"additional","affiliation":[{"name":"Crown Princess Mary Cancer Centre Westmead Hospital  Westmead New South Wales Australia"},{"name":"Blacktown Cancer and Haematology Centre Blacktown Hospital  Blacktown New South Wales Australia"},{"name":"School of Physics, Institute of Medical Physics University of Sydney  Camperdown New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yolanda","family":"Surjan","sequence":"additional","affiliation":[{"name":"College of Health Medicine and Wellbeing  Callaghan New South Wales Australia"},{"name":"The University of Newcastle  Callaghan New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0040-4772","authenticated-orcid":false,"given":"Rachael","family":"Beldham\u2010Collins","sequence":"additional","affiliation":[{"name":"Crown Princess Mary Cancer Centre Westmead Hospital  Westmead New South Wales Australia"},{"name":"Blacktown Cancer and Haematology Centre Blacktown Hospital  Blacktown New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Murphy","sequence":"additional","affiliation":[{"name":"Radiation Oncology Peter MacCallum Cancer Centre  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Fernandez","sequence":"additional","affiliation":[{"name":"Crown Princess Mary Cancer Centre Westmead Hospital  Westmead New South Wales Australia"},{"name":"Blacktown Cancer and Haematology Centre Blacktown Hospital  Blacktown New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alison","family":"Salkeld","sequence":"additional","affiliation":[{"name":"Crown Princess Mary Cancer Centre Westmead Hospital  Westmead New South Wales Australia"},{"name":"School of Physics, Institute of Medical Physics University of Sydney  Camperdown New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,6,29]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/mpo.10121"},{"key":"e_1_2_10_3_1","unstructured":"Australian Government Australian Institute of Health and Welfare \u201cCancer Data in Australia: Canberra \u201d2022[updated 25\/11\/2022; cited 2023. 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