{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T03:25:22Z","timestamp":1792121122166,"version":"4.4.0"},"reference-count":38,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,11,11]],"date-time":"2023-11-11T00:00:00Z","timestamp":1699660800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003977","name":"Israel Science Foundation","doi-asserted-by":"publisher","award":["312\/22"],"award-info":[{"award-number":["312\/22"]}],"id":[{"id":"10.13039\/501100003977","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006031","name":"United States - Israel Binational Agricultural Research and Development Fund","doi-asserted-by":"publisher","award":["IS\u20105451\u201021"],"award-info":[{"award-number":["IS\u20105451\u201021"]}],"id":[{"id":"10.13039\/100006031","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Mass Spectrom"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Saliva is a body fluid that is much easier to collect and analyze than blood. Thus, saliva analysis for the detection of delta 9\u2010tetrahydrocannabinol (delta 9\u2010THC) can serve as a tool for law enforcement agents to detect cannabis consumption by drivers. Fast saliva analysis for the presence of delta 9\u2010THC and\/or cannabidiol (CBD) is described with both gas chromatography\u2013mass spectrometry (GC\u2013MS) with Cold electron ionization (EI) with good separation and in 10\u00a0min and\/or with Open Probe Fast GC\u2013MS with Cold EI in under 1\u2009min full analysis cycle time. Saliva was taken directly from donors' tongues on a thin glass rod that was used \u201cas is\u201d for analysis. The saliva was thermally desorbed with a modified ChromatoProbe device inside the gas chromatograph (GC) injector and in an Open Probe (Agilent name QuickProbe) for its sub\u20101\u2010min analysis. Cold EI is based on coupling of the GC and mass spectrometer (MS) with a supersonic molecular beam and on EI of vibrationally cold sample molecules during their flight through a contact\u2010free ion source (thereby named Cold EI). A revised type of Open Probe Fast GC\u2013MS on the bench is also described. Our saliva analysis was characterized by:\n                    <jats:list>\n                      <jats:list-item>\n                        <jats:p>Saliva can be collected in the field and transported to the lab for analyses \u201cas is\u201d without any sample preparation.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>Easy detection of cannabis consumption from cigarettes and\/or other cannabis products.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>Distinction between the isomers delta 9\u2010THC and CBD.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>Ultra\u2010fast analysis in under 1\u2009min using Open Probe Fast GC\u2013MS with Cold EI.<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:p>","DOI":"10.1002\/jms.4981","type":"journal-article","created":{"date-parts":[[2023,11,11]],"date-time":"2023-11-11T07:00:45Z","timestamp":1699686045000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Fast saliva analysis by GC\u2013MS with Cold EI and Open Probe Fast GC\u2013MS with Cold EI for the detection of cannabis usage"],"prefix":"10.1002","volume":"58","author":[{"given":"Oneg","family":"Elkabets","sequence":"first","affiliation":[{"name":"School of Chemistry Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benny","family":"Neumark","sequence":"additional","affiliation":[{"name":"School of Chemistry Tel Aviv University  Tel Aviv 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