{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T16:56:17Z","timestamp":1790873777005,"version":"4.1.0"},"reference-count":22,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T00:00:00Z","timestamp":1754956800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Mass Spectrom"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>To enrich detection methods of Saposhnikoviae Radix (SR) adulterated Libonotidis Radix (LR) and improve the screening efficiency, this paper conducted an analysis of SR and LR based on chemometrics and \u201ccharacteristic ion set.\u201d Firstly, the samples were analyzed by liquid chromatography\u2010mass spectrometer and converted into data matrix. After feature algorithm extraction, the \u201ccharacteristic ion set\u201d of SR and LR was obtained to match the test and blind market samples for feedback matching index (MI). In addition, the LR proprietary component was extracted to verify the MI analysis based on \u201ccharacteristic ion set.\u201d Three percent LR adulteration was identified based on \u201ccharacteristic ion set,\u201d and two market blind samples were identified as adulterated samples. Xanthalin was the LR proprietary component. Moreover, the analysis based on \u201ccharacteristic ion set\u201d is reliable through chemometric analysis and extraction of proprietary ions. \u201cCharacteristic ion set\u201d and chemometrics can enrich the detection methods of SR and LR and improve the screening efficiency.<\/jats:p>","DOI":"10.1002\/jms.5164","type":"journal-article","created":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T18:19:50Z","timestamp":1755022790000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Analysis of Saposhnikoviae Radix and Libonotidis Radix Based on \u201cCharacteristic Ion Set\u201d and Chemometrics"],"prefix":"10.1002","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9793-9596","authenticated-orcid":false,"given":"Xianrui","family":"Wang","sequence":"first","affiliation":[{"name":"Institute for Control of Traditional Chinese Medicine and Ethnic Medicine National Institutes for Food and Drug Control  Beijing People's Republic of China"},{"name":"State Key Laboratory of Drug Regulatory Science National Institutes for Food and Drug Control  Beijing People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangliang","family":"He","sequence":"additional","affiliation":[{"name":"Institute for Control of Traditional Chinese Medicine and Ethnic Medicine National Institutes for Food and Drug Control  Beijing People's Republic of China"},{"name":"State Key Laboratory of Drug Regulatory Science National Institutes for Food and Drug Control  Beijing People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8753-7908","authenticated-orcid":false,"given":"Haonan","family":"Wu","sequence":"additional","affiliation":[{"name":"Institute for Control of Traditional Chinese Medicine and Ethnic Medicine National Institutes for Food and Drug Control  Beijing People's Republic of China"},{"name":"Faculty of Functional Food and Wine Shenyang Pharmaceutical University  Shenyang People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenguang","family":"Jing","sequence":"additional","affiliation":[{"name":"Institute for Control of Traditional Chinese Medicine and Ethnic Medicine National Institutes for Food and Drug Control  Beijing People's Republic of China"},{"name":"State Key Laboratory of Drug Regulatory Science National Institutes for Food and Drug Control  Beijing People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minghua","family":"Li","sequence":"additional","affiliation":[{"name":"Institute for Control of Traditional Chinese Medicine and Ethnic Medicine National Institutes for Food and Drug Control  Beijing People's Republic of China"},{"name":"State Key Laboratory of Drug Regulatory Science National Institutes for Food and Drug Control  Beijing People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohan","family":"Guo","sequence":"additional","affiliation":[{"name":"Institute for Control of Traditional Chinese Medicine and Ethnic Medicine National Institutes for Food and Drug Control  Beijing People's Republic of China"},{"name":"State Key Laboratory of Drug Regulatory Science National Institutes for Food and Drug Control  Beijing People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianlong","family":"Cheng","sequence":"additional","affiliation":[{"name":"Institute for Control of Traditional Chinese Medicine and Ethnic Medicine National Institutes for Food and Drug Control  Beijing People's Republic of China"},{"name":"State Key Laboratory of Drug Regulatory Science National Institutes for Food and Drug Control  Beijing People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Wei","sequence":"additional","affiliation":[{"name":"Institute for Control of Traditional Chinese Medicine and Ethnic Medicine National Institutes for Food and Drug Control  Beijing People's Republic of China"},{"name":"State Key Laboratory of Drug Regulatory Science National Institutes for Food and Drug Control  Beijing People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8,12]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2023.116956"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11655\u2010020\u20103091\u2010x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.19540\/j.cnki.cjcmm.20190604.201"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.19540\/j.cnki.cjcmm.20230314.101"},{"issue":"1","key":"e_1_2_10_6_1","first-page":"20","article-title":"Comparative Studies on the Febrifugal and Analgesic Activities of Chinese Drug Fang\u2010Feng, Root of Saposhnikovia divaricata (Turcz.) 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